Chapter 1 Gender Differences in Pharmacological Response

High Blood Alcohol Levels in Women

1990 • 1,248 citations

The Human Hepatic Cytochromes P450 Involved in Drug Metabolism

1992 • 932 citations

A Gender Gap in Autoimmunity

1999 • 856 citations

Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs

1993 • 843 citations

Association of Serum Digoxin Concentration and Outcomes in Patients With Heart Failure

2003 • 732 citations

Female Gender as a Risk Factor for Torsades de Pointes Associated With Cardiovascular Drugs

1993 • 702 citations

Sex-Based Differences in the Effect of Digoxin for the Treatment of Heart Failure

2002 • 680 citations

DRUG-INDUCED LIVER DISEASE

2000 • 521 citations

Valproic acid hepatic fatalities

1987 • 491 citations

Sex is a major determinant of CYP3A4 expression in human liver

2003 • 471 citations

Sex and Racial Differences in Pharmacological Response: Where Is the Evidence? Pharmacogenetics, Pharmacokinetics, and Pharmacodynamics

2005 • 309 citations

Epidemiology of drug exposure and adverse drug reactions in two Swiss departments of internal medicine

2000 • 304 citations

Drug-Induced QT Prolongation in Women During the Menstrual Cycle

2001 • 301 citations

Comparison and predictors of rash associated with 15 antiepileptic drugs

2007 • 274 citations

Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms.

1995 • 254 citations

The Current State of Knowledge on Age, Sex, and Their Interactions on Clinical Pharmacology

2007 • 243 citations

Is Gender a Risk Factor for Adverse Drug Reactions?

2001 • 223 citations

Specificity of human UDP-Glucuronosyltransferases and xenobiotic glucuronidation

1995 • 220 citations

Sex is a major determinant of CYP3A4 expression in human liver

2003 • 213 citations

Gender Differences in Adverse Drug Reactions

1998 • 207 citations

Sex‐related differences in the clearance of cytochrome P450 3A4 substrates may be caused by P‐glycoprotein

2002 • 158 citations

Women Subjects in NIH-Funded Clinical Research Literature: Lack of Progress in Both Representation and Analysis by Sex

2000 • 152 citations

Body Mass Index, Weight, and Oral Contraceptive Failure Risk

2005 • 151 citations

Gender-Based Differences in the Toxicity of Pharmaceuticals—The Food and Drug Administration's Perspective

2001 • 143 citations

Factors Influencing the Incidence of Lamotrigine-Related Skin Rash

1999 • 131 citations

Pharmacokinetic analysis of bioequivalence trials: Implications for sex-related issues in clinical pharmacology and biopharmaceutics

2000 • 108 citations

Hepatic Considerations in the Use of Antiepileptic Drugs

1987 • 101 citations

Gender differences in autoimmunity: molecular basis for estrogen effects in systemic lupus erythematosus

2001 • 100 citations

The Disproportionate Impact of Chronic Arthralgia and Arthritis Among Women

2000 • 91 citations

Effect of food on the absorption of enteric-coated aspirin: Correlation with gastric residence time

1987 • 84 citations

Female sex as a risk factor for penicillin allergy

2007 • 81 citations

Sex-related variations in the frequency and characteristics of adverse drug reactions.

1980 • 67 citations

Fatal progressive hepatic necrosis associated with lamotrigine treatment: a case report and literature review.

2002 • 59 citations

Carbamazepine-induced skin rash in children with epilepsy

1993 • 42 citations

Effect of age and sex on glomerular filtration rate measured by 51Cr-EDTA.

1992 • 41 citations

Rash Complicating Carbamazepine Treatment

1994 • 40 citations

Sex differences in HIV: Natural history, pharmacokinetics, and drug toxicity

2005 • 13 citations