Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis

MicroRNAs

2004 • 33,206 citations

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1993 • 12,238 citations

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

2007 • 11,510 citations

MicroRNA expression profiles classify human cancers

2005 • 9,457 citations

Circulating microRNAs as stable blood-based markers for cancer detection

2008 • 7,573 citations

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

2008 • 4,620 citations

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

2008 • 4,359 citations

Biogenesis of small RNAs in animals

2009 • 3,094 citations

Causes and consequences of microRNA dysregulation in cancer

2009 • 2,879 citations

RETRACTED: MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer

2008 • 2,230 citations

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

2008 • 1,869 citations

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

2010 • 1,844 citations

Detection of elevated levels of tumour‐associated microRNAs in serum of patients with diffuse large B‐cell lymphoma

2008 • 1,692 citations

Shedding microvesicles: artefacts no more

2009 • 1,679 citations

Functional delivery of viral miRNAs via exosomes

2010 • 1,541 citations

Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

2001 • 1,538 citations

Detection of microRNA Expression in Human Peripheral Blood Microvesicles

2008 • 1,408 citations

Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection

2009 • 1,266 citations

Exosomal MicroRNA: A Diagnostic Marker for Lung Cancer

2009 • 1,195 citations

Small-cell lung cancer

2011 • 1,170 citations

Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening

2009 • 1,120 citations

Identification of Tim4 as a phosphatidylserine receptor

2007 • 1,092 citations

MicroRNAs accurately identify cancer tissue origin

2008 • 975 citations

Mechanisms and optimization of in vivo delivery of lipophilic siRNAs

2007 • 909 citations

Salivary microRNA: Discovery, Characterization, and Clinical Utility for Oral Cancer Detection

2009 • 801 citations

Serum MicroRNA Signatures Identified in a Genome-Wide Serum MicroRNA Expression Profiling Predict Survival of Non–Small-Cell Lung Cancer

2010 • 784 citations

Mature miR-184 as Potential Oncogenic microRNA of Squamous Cell Carcinoma of Tongue

2008 • 746 citations

Exosomes from human saliva as a source of microRNA biomarkers

2009 • 676 citations

Circulating microRNAs as Novel Minimally Invasive Biomarkers for Breast Cancer

2010 • 674 citations

The detection of differentially expressed microRNAs from the serum of ovarian cancer patients using a novel real-time PCR platform

2008 • 642 citations

Circulating microRNAs in plasma of patients with gastric cancers

2010 • 614 citations

MicroRNAs in Plasma of Pancreatic Ductal Adenocarcinoma Patients as Novel Blood-Based Biomarkers of Disease

2009 • 540 citations

microRNA as a new immune-regulatory agent in breast milk

2010 • 514 citations

Transfer of MicroRNAs by Embryonic Stem Cell Microvesicles

2009 • 411 citations

Circulating microRNAs in breast cancer and healthy subjects

2009 • 357 citations

Horizontal Transfer of DNA by the Uptake of Apoptotic Bodies

1999 • 318 citations

Down-Regulation of miR-92 in Human Plasma Is a Novel Marker for Acute Leukemia Patients

2009 • 295 citations

Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer

2010 • 278 citations

Characterization of Amplifiable, Circulating RNA in Plasma and Its Potential as a Tool for Cancer Diagnostics

2004 • 271 citations

Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner

2009 • 236 citations

Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression

2009 • 222 citations

MicroRNA-500 as a potential diagnostic marker for hepatocellular carcinoma

2009 • 206 citations

Cell contact-dependent acquisition of cellular and viral nonautonomously encoded small RNAs

2009 • 118 citations

Prostasomes—their effects on human male reproduction and fertility

2005 • 109 citations

Transfer of functional prostasomal CD59 of metastatic prostatic cancer cell origin protects cells against complement attack

2004 • 50 citations

Ectopic expression of systemic RNA interference defective protein in embryonic stem cells

2007 • 35 citations