Transcription factor E2F binds DNA as a heterodimer.

The E2F transcription factor is a cellular target for the RB protein

1991 • 1,461 citations

Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

1992 • 846 citations

Retinoblastoma protein switches the E2F site from positive to negative element

1992 • 663 citations

A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

1992 • 652 citations

The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner

1992 • 588 citations

Identification of a cellular transcription factor involved in E1A trans-activation

1986 • 551 citations

The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F

1991 • 446 citations

The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein

1991 • 420 citations

Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A

1991 • 374 citations

Transcriptional regulation by dimerization: Two sides to an incestuous relationship

1990 • 343 citations

Cyclin A and the retinoblastoma gene product complex with a common transcription factor

1991 • 296 citations

Transcription Factor E2F Is Required for Efficient Expression of the Hamster Dihydrofolate Reductase Gene In Vitro and In Vivo

1989 • 292 citations

A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway.

1990 • 253 citations

The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression.

1992 • 239 citations

The adenovirus E4 17-kilodalton protein complexes with the cellular transcription factor E2F, altering its DNA-binding properties and stimulating E1A-independent accumulation of E2 mRNA

1990 • 145 citations

The adenovirus-inducible factor E2F stimulates transcription after specific DNA binding.

1989 • 137 citations

Identification of an E1A-inducible cellular factor that interacts with regulatory sequences within the adenovirus E4 promoter.

1987 • 133 citations

Protein domains governing interactions between E2F, the retinoblastoma gene product, and human papillomavirus type 16 E7 protein.

1993 • 128 citations

A closer look at E2F

1992 • 95 citations

The adenovirus E4 gene, in addition to the E1A gene, is important for trans-activation of E2 transcription and for E2F activation

1989 • 83 citations

Rapid purification and characterisation of HIV‐1 reverse transcriptase and RNaseH engineered to incorporate a C‐terminal tripeptide α‐tubulin epitope

1991 • 55 citations

The Adenovirus-Inducible Factor E2F Stimulates Transcription after Specific DNA Binding

1989 • 52 citations

Complexes containing the retinoblastoma gene product recognize different DNA motifs related to the E2F binding site.

1992 • 31 citations

Identification of a 60-Kilodalton Rb-Binding Protein, RBP60, That Allows the Rb-E2F Complex To Bind DNA

1992 • 27 citations

Control of Cellular and Viral Transcription During Adenovirus Infectio

1986 • 27 citations

Purification and characterization of a functionally homogeneous 60-kDa species of the retinoblastoma gene product.

1992 • 22 citations