The Nonclassical MHC Class I Molecule Qa-1 Forms Unstable Peptide Complexes

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

MHC ligands and peptide motifs: first listing

1995 • 1,674 citations

HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

1998 • 998 citations

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by CD94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis

1998 • 706 citations

HLA-E Surface Expression Depends on Binding of TAP-Dependent Peptides Derived from Certain HLA Class I Signal Sequences

1998 • 495 citations

Mouse CD94/NKG2A Is a Natural Killer Cell Receptor for the Nonclassical Major Histocompatibility Complex (MHC) Class I Molecule Qa-1b

1998 • 491 citations

Immunogenicity of peptides bound to MHC class I molecules depends on the MHC-peptide complex stability.

1996 • 389 citations

Dissecting the Multifactorial Causes of Immunodominance in Class I–Restricted T Cell Responses to Viruses

2000 • 312 citations

Importance of Peptide Amino and Carboxyl Termini to the Stability of MHC Class I Molecules

1994 • 294 citations

Identification of a tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen

1994 • 275 citations

Recognition of the Class Ib Molecule Qa-1b by Putative Activating Receptors Cd94/Nkg2c and Cd94/Nkg2e on Mouse Natural Killer Cells

1999 • 233 citations

CD94-NKG2A receptors regulate antiviral CD8+ T cell responses

2002 • 225 citations

Determinant selection of major histocompatibility complex class I-restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues.

1994 • 216 citations

Structural Features Impose Tight Peptide Binding Specificity in the Nonclassical MHC Molecule HLA-E

1998 • 206 citations

SingleH2Kb, H2Db and doubleH2KbDb knockout mice: peripheral CD8+ T cell repertoire and antilymphocytic choriomeningitis virus cytolytic responses

1999 • 198 citations

Intramembrane Proteolysis of Signal Peptides: An Essential Step in the Generation of HLA-E Epitopes

2001 • 177 citations

The Specific Regulation Of Immune Responses By CD8⁺T Cells Restricted By The MHC Class Ib Molecule, Qa-1

2000 • 168 citations

Molecular mimicry mediated by MHC class Ib molecules after infection with Gram-negative pathogens

2000 • 153 citations

The life span of major histocompatibility complex-peptide complexes influences the efficiency of presentation and immunogenicity of two class I-restricted cytotoxic T lymphocyte epitopes in the Epstein-Barr virus nuclear antigen 4.

1996 • 132 citations

Analysis of Qa-1bPeptide Binding Specificity and the Capacity of Cd94/Nkg2a to Discriminate between Qa-1–Peptide Complexes

2000 • 117 citations

Dominance of a single peptide bound to the class I(B) molecule, Qa-1b.

1997 • 103 citations

Cutting Edge: Expression of Functional CD94/NKG2A Inhibitory Receptors on Fetal NK1.1+Ly-49− Cells: A Possible Mechanism of Tolerance During NK Cell Development

1999 • 84 citations

The Qa-1b molecule binds to a large subpopulation of murine NK cells

1998 • 76 citations

Positive Selection of a Qa-1-Restricted T Cell Receptor with Specificity for Insulin

2002 • 71 citations

MHC class Ib-restricted cells contribute to antilisterial immunity: evidence for Qa-1b as a key restricting element for Listeria-specific CTLs.

1997 • 69 citations

Qa‐1 interaction and T cell recognition of the Qa‐1 determinant modifier peptide

1997 • 63 citations

A Peptide from Heat Shock Protein 60 Is the Dominant Peptide Bound To Qa-1 in the Absence of the MHC Class Ia Leader Sequence Peptide Qdm

2003 • 61 citations

Formation and Kinetics of MHC Class I-Ovalbumin Peptide Complexes on Immature and Mature Murine Dendritic Cells

2000 • 61 citations

Processing of Exogenous Antigens for Presentation by Class I MHC Molecules Involves Post-Golgi Peptide Exchange Influenced by Peptide-MHC Complex Stability and Acidic pH

2001 • 58 citations

Transporters Associated with Antigen Processing (TAP)-independent Presentation of Soluble Insulin to α/β T Cells by the Class Ib Gene Product, Qa-1b

1998 • 51 citations

The TL region gene 37 encodes a Qa-1 antigen.

1990 • 39 citations

Peptide binding to the class Ib molecule, Qa-1b.

1997 • 36 citations

The Pathway for Processing Leader-Derived Peptides that Regulate the Maturation and Expression of Qa-1b

1998 • 33 citations

Stability of Surface H-2Kb, H-2Db, and Peptide-Receptive H-2Kb on Splenocytes

2001 • 29 citations

The mechanisms of peptide exchange and beta 2-microglobulin exchange on cell surface Ld and Kb molecules are noncooperative.

1996 • 26 citations

The lifespan of major histocompatibility complex class I/peptide complexes determines the efficiency of cytotoxic T‐lymphocyte responses

1999 • 23 citations

Functional Analysis of the Molecular Factors Controlling Qa1-Mediated Protection of Target Cells from NK Lysis

2001 • 21 citations

Soluble MHC class I molecules induce cellular death in a CD8 T‐cell hybridoma tumor model

2001 • 4 citations