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An amino-acid taste receptor

2002 • 1,419 citations

Human receptors for sweet and umami taste

2002 • 1,278 citations

Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits

1991 • 1,076 citations

Regulation and Role of Adenylyl Cyclase Isoforms

2001 • 666 citations

Gustducin is a taste-cell-specific G protein closely related to the transducins

1992 • 662 citations

Receptors and transduction in taste

2001 • 649 citations

Adenylyl cyclases and the interaction between calcium and cAMP signalling

1995 • 594 citations

A metabotropic glutamate receptor variant functions as a taste receptor

2000 • 587 citations

Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4

1993 • 585 citations

A transient receptor potential channel expressed in taste receptor cells

2002 • 501 citations

Disruption of the Type III Adenylyl Cyclase Gene Leads to Peripheral and Behavioral Anosmia in Transgenic Mice

2000 • 460 citations

Molecular Mechanisms of Bitter and Sweet Taste Transduction

2002 • 434 citations

Structure of the adenylyl cyclase catalytic core

1997 • 388 citations

Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation

2002 • 352 citations

Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases.

1994 • 351 citations

Gγ13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium

1999 • 332 citations

Sensory transduction in vomeronasal neurons: evidence for G alpha o, G alpha i2, and adenylyl cyclase II as major components of a pheromone signaling cascade

1996 • 297 citations

Cloning and expression of a Ca(2+)-inhibitable adenylyl cyclase from NCB-20 cells.

1992 • 262 citations

The molecular physiology of taste transduction

2000 • 259 citations

“Type III” cells of rat taste buds: Immunohistochemical and ultrastructural studies of neuron‐specific enolase, protein gene product 9.5, and serotonin

2001 • 255 citations

G protein regulation of adenylate cyclase

1999 • 231 citations

Molecular biological approaches to unravel adenylyl cyclase signaling and function

2001 • 175 citations

Sweet tastants stimulate adenylate cyclase coupled to GTP-binding protein in rat tongue membranes

1989 • 167 citations

Proton currents through amiloride-sensitive Na+ channels in isolated hamster taste cells: Enhancement by vasopressin and cAMP

1993 • 156 citations

Calmodulin-regulated adenylyl cyclases and neuromodulation

1997 • 138 citations

Differential Expression of α-Gustducin in Taste Bud Populations of the Rat and Hamster

1997 • 136 citations

Electrophysiological and behavioral studies on the taste of umami substances in the rat

1991 • 119 citations

Bitter taste transduced by PLC-β₂-dependent rise in IP₃ and α-gustducin-dependent fall in cyclic nucleotides

2001 • 112 citations

Phosphodiesterase in Tongue Epithelium: Activation by Bitter Taste Stimuli

1973 • 95 citations

Inhibition of adenylyl cyclase isoforms V and VI by various G_βγsubunits

1998 • 89 citations

Regulation of a Ca2+-sensitive Adenylyl Cyclase in an Excitable Cell

2000 • 86 citations

Behavioral Evidence for a Role of -Gustducin in Glutamate Taste

2003 • 84 citations

Generation of Cyclic AMP in Taste Buds of the Rat Circumvallate Papilla in Response to Sucrose

1991 • 82 citations

Physiological Evidence for Ionotropic and Metabotropic Glutamate Receptors in Rat Taste Cells

1999 • 81 citations

Factors Determining the Specificity of Signal Transduction by Guanine Nucleotide-binding Protein-coupled Receptors

1997 • 79 citations

Splice Variants of Type VIII Adenylyl Cyclase

1996 • 77 citations

Gustatory neural responses in preweanling mice

1991 • 76 citations

Comprehensive Study on G protein alpha-Subunits in Taste Bud Cells, with Special Reference to the Occurrence of Galphai2 as a Major Galpha Species

2000 • 73 citations

Responses to Glutamate in Rat Taste Cells

1997 • 69 citations

Gi-mediated stimulation of type II adenylyl cyclase is augmented by Gq-coupled receptor activation and phorbol ester treatment.

1996 • 66 citations

Taste Receptor Cell Responses to the Bitter Stimulus Denatonium Involve Ca²⁺ Influx Via Store-Operated Channels

2002 • 63 citations

The Taste of Monosodium Glutamate (MSG), L-Aspartic Acid, and N-Methyl-D-aspartate (NMDA) in Rats: Are NMDA Receptors Involved in MSG Taste?

1999 • 55 citations

Differential expression of adenylyl cyclases in the rat nephron

2001 • 54 citations

Co-expression of calcium signaling components in vertebrate taste bud cells

2000 • 53 citations

Gi-mediated stimulation of type II adenylyl cyclase is augmented by Gq- coupled receptor activation and phorbol ester treatment

1996 • 52 citations

Analyses of taste nerve responses with special reference to possible receptor mechanisms of umami taste in the rat

1999 • 44 citations

Taste Preference Synergy Between Glutamate Receptor Agonists and Inosine Monophosphate in Rats

2000 • 42 citations

Excitation and Adaptation in the Detection of Hydrogen Ions by Taste Receptor Cells: A Role for cAMP and Ca²⁺

2002 • 40 citations

Gβ Association and Effector Interaction Selectivities of the Divergent Gγ Subunit Gγ13

2001 • 37 citations

Galanthamine Hydrobromide in a Long-Term Treatment of Alzheimer's Disease

1990 • 35 citations

Transduction for Sweet Taste of Saccharin May Involve Both Inositol 1,4,5-Trisphosphate and cAMP Pathways in the Fungiform Taste Buds in C57BL Mice

1999 • 34 citations

Adenylyl Cyclase Type II Domains Involved in Gβγ Stimulation

2001 • 33 citations

Role of G Proteins in Transmembrane Signaling

1988 • 32 citations

Sucrose-stimulated subsecond transient increase in cGMP level in rat intact circumvallate taste bud cells

2000 • 26 citations

Inhibition of adenylyl cyclase isoforms V and VI by various Gbg subunits

1998 • 17 citations

Responses to Monosodium Glutamate and Guanosine 5'-Monophosphate in Rat Fungiform Taste Cellsa

1998 • 11 citations

Assaying G Protein–Phosphodiesterase Interactions in Sensory Systems

2002 • 8 citations