The H3-H4 N-Terminal Tail Domains Are the Primary Mediators of Transcription Factor IIIA Access to 5S DNA within a Nucleosome

Crystal structure of the nucleosome core particle at 2.8 Å resolution

1997 • 8,906 citations

Roles of histone acetyltransferases and deacetylases in gene regulation

1998 • 1,207 citations

A positive role for histone acetylation in transcription factor access to nucleosomal DNA

1993 • 1,116 citations

Chromatin Structure and Function

1979 • 1,050 citations

Chromatin as an essential part of the transcriptional mechanim

1992 • 853 citations

Mechanism of Protein Access to Specific DNA Sequences in Chromatin: A Dynamic Equilibrium Model for Gene Regulation

1995 • 651 citations

Disruption of Higher-Order Folding by Core Histone Acetylation Dramatically Enhances Transcription of Nucleosomal Arrays by RNA Polymerase III

1998 • 568 citations

Chromatin disruption and modification

1999 • 537 citations

Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation

1996 • 525 citations

Transcription of Class III Genes: Formation of Preinitiation Complexes

1983 • 492 citations

Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro.

1996 • 469 citations

Chromatin Structure and Function

1999 • 438 citations

Histone acetylation reduces nucleosome core particle linking number change

1989 • 394 citations

The structure of DNA in a nucleosome.

1990 • 353 citations

ATP-Dependent Histone Octamer Sliding Mediated by the Chromatin Remodeling Complex NURF

1999 • 334 citations

Use of selectively trypsinized nucleosome core particles to analyze the role of the histone “tails” in the stabilization of the nucleosome

1989 • 330 citations

Modulation of Chromatin Folding by Histone Acetylation

1995 • 311 citations

Nucleosome positioning can affect the function of a cis-acting DMA elementin vivo

1990 • 305 citations

Contact points between a positive transcription factor and the Xenopus 5S RNA gene

1982 • 291 citations

Participation of core histone "tails" in the stabilization of the chromatin solenoid.

1982 • 264 citations

Domains of the positive transcription factor specific for the Xenopus 5S RNA gene

1984 • 262 citations

Histone contributions to the structure of DNA in the nucleosome.

1991 • 256 citations

A Model for the Cooperative Binding of Eukaryotic Regulatory Proteins to Nucleosomal Target Sites

1996 • 251 citations

Structure and Function of the Core Histone N-Termini: More Than Meets the Eye

1998 • 241 citations

Role of the histone “tails” in the folding of oligonucleosomes depleted of histone H1.

1992 • 238 citations

Developmental Regulation of Two 5 S Ribosomal RNA Genes

1988 • 229 citations

Specific regulation of Xenopus chromosomal 5S rRNA gene transcription in vivo by histone H1.

1994 • 228 citations

Structural analysis of a triple complex between the histone octamer, a Xenopus gene for 5S RNA and transcription factor IIIA.

1985 • 222 citations

Assembly of transcriptionally active 5S RNA gene chromatin in vitro

1982 • 195 citations

Mapping nucleosome position at single base-pair resolution by using site-directed hydroxyl radicals.

1996 • 175 citations

A positive role for nucleosome mobility in the transcriptional activity of chromatin templates: restriction by linker histones.

1995 • 172 citations

Linker histones H1 and H5 prevent the mobility of positioned nucleosomes.

1994 • 168 citations

Formation and stability of higher order chromatin structures. Contributions of the histone octamer.

1994 • 163 citations

A functional role for nucleosomes in the repression of a yeast promoter.

1991 • 156 citations

Role of the Histone Amino Termini in Facilitated Binding of a Transcription Factor, GAL4-AH, to Nucleosome Cores

1994 • 136 citations

Nucleosome Structural Changes Due to Acetylation

1994 • 133 citations

Nucleosome linking number change controlled by acetylation of histones H3 and H4.

1990 • 132 citations

Histones H2A/H2B inhibit the interaction of transcription factor IIIA with the Xenopus borealis somatic 5S RNA gene in a nucleosome.

1992 • 123 citations

Proteolytic Digestion Studies of Chromatin Core‐Histone Structure

1980 • 96 citations

Histones as Regulators of Genes

1992 • 92 citations

Effect of Acetylation on the Binding of N-Terminal Peptides of Histone H4 to DNA

1982 • 85 citations

The amino-terminal tails of the core histones and the translational position of the TATA box determine TBP/TFIIA association with nucleosomal DNA

1995 • 84 citations

A role for histones H2A/H2B in chromatin folding and transcriptional repression.

1994 • 84 citations

Role of Histone H1 as an Architectural Determinant of Chromatin Structure and as a Specific Repressor of Transcription onXenopus Oocyte 5S rRNA Genes

1998 • 82 citations

Contacts of the globular domain of histone H5 and core histones with DNA in a "chromatosome".

1994 • 81 citations

Transient activation of oocyte 5S RNA genes in Xenopus embryos by raising the level of the Trans-acting factor TFIIIA

1987 • 75 citations

The N-terminal tail of histone H2A binds to two distinct sites within the nucleosome core

1997 • 62 citations

Differential nucleosome positioning on Xenopus oocyte and somatic 5 s RNA genes determines both TFIIIA and H1 binding: a mechanism for selective H1 repression 1 1Edited by J. Karn

1998 • 61 citations

Linker DNA and H1-Dependent Reorganization of Histone−DNA Interactions within the Nucleosome

1998 • 60 citations

The transcription complex of the 5 S RNA gene, but not transcription factor IIIA alone, prevents nucleosomal repression of transcription.

1990 • 59 citations

Histone-DNA contacts in a nucleosome core containing a Xenopus 5S rRNA gene

1993 • 55 citations

Proteolytic Digestion Studies of Chromatin Core‐Histone Structure

1982 • 54 citations

Superhelical stress and nucleosome-mediated repression of 5S RNA gene transcription in vitro.

1991 • 54 citations

High yield purification of active transcription factor IIIA expressed inE.coli

1991 • 38 citations

Nucleosome Translational Position, Not Histone Acetylation, Determines TFIIIA Binding to Nucleosomal Xenopus laevis 5S rRNA Genes

1998 • 35 citations

Enhanced transcription factor access to arrays of histone H3/H4 tetramer⋅DNA complexes in vitro : Implications for replication and transcription

1998 • 31 citations

Transcriptionally Active Xenopus laevis Somatic 5 S Ribosomal RNA Genes Are Packaged with Hyperacetylated Histone H4, Whereas Transcriptionally Silent Oocyte Genes Are Not

1998 • 31 citations

Binding of Retinoic Acid Receptor Heterodimers to DNA

1998 • 27 citations

Functionally Relevant Histone-DNA Interactions Extend Beyond the Classically Defined Nucleosome Core Region

1998 • 26 citations

Rapid and effective Western blotting of histones from acid‐urea‐Triton and sodium docecyl sulfate polyacrylamide gels: Two different approaches depending on the subsequent qualitative or quantitative analysis

1995 • 20 citations

Both the 5S rRNA gene and the AT-rich flanks of xenopus laevis oocyte- type 5S rDNA repeat are required for histone H1-dependent repression of transcription of pol III-type genes in in vitro reconstituted chromatin

1998 • 14 citations

Antisera Directed against Anti-Histone H4 Antibodies Recognize Linker Histones

1997 • 7 citations