Association Between Glutathione S-Transferase P1, T1, and M1 Genetic Polymorphism and Survival of Patients With Metastatic Colorectal Cancer

Toxicity and response criteria of the Eastern Cooperative Oncology Group

1982 • 10,605 citations

Statistical Models and Methods for Lifetime Data

2002 • 4,035 citations

Survival Analysis

1981 • 3,421 citations

Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics

1999 • 2,458 citations

Tumor Microsatellite Instability and Clinical Outcome in Young Patients with Colorectal Cancer

2000 • 1,352 citations

A Network Algorithm for Performing Fisher's Exact Test inr×cContingency Tables

1983 • 916 citations

Identification of genetic polymorphisms at the glutathione S- transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer

1997 • 749 citations

Human glutathione S-transferase P1 polymorphisms: relationship to lung tissue enzyme activity and population frequency distribution

1998 • 678 citations

Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy

2001 • 569 citations

Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer

2000 • 556 citations

Glutathione Transferases and Cancer

1992 • 548 citations

Oxaliplatin: mechanism of action and antineoplastic activity.

1998 • 507 citations

Zeta, a novel class of glutathione transferases in a range of species from plants to humans

1997 • 498 citations

A Network Algorithm for Performing Fisher's Exact Test in r × c Contingency Tables

1983 • 485 citations

Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: a prospective study of men in Shanghai, China

2000 • 444 citations

A Multiplex Polymerase Chain Reaction Protocol for the Simultaneous Analysis of the GlutathioneS-Transferase GSTM1 and GSTT1 Polymorphisms

1996 • 348 citations

Expression of anionic glutathione-S-transferase and P-glycoprotein genes in human tissues and tumors.

1989 • 347 citations

Polymorphism in glutathione S -transferase P1 is associated with susceptibility to chemotherapy-induced leukemia

2001 • 258 citations

Glutathione S-transferase and glutathione peroxidase expression in normal and tumour human tissues

1990 • 238 citations

Polymorphisms of N-Acetyltransferases, Glutathione S-Transferases, Microsomal Epoxide Hydrolase and Sulfotransferases: Influence on Cancer Susceptibility

1998 • 237 citations

Transfection of glutathione S-transferase (GST)-pi antisense complementary DNA increases the sensitivity of a colon cancer cell line to adriamycin, cisplatin, melphalan, and etoposide.

1996 • 187 citations

Overexpression of glutathione S-transferase π enhances the adduct formation of cisplatin with glutathione in human cancer cells

1999 • 184 citations

Polymorphisms in glutathione S-transferases (GSTM1 and GSTT1) and survival after treatment for breast cancer.

2001 • 173 citations

Glutathione S-Transferase Polymorphisms and Outcome of Chemotherapy in Childhood Acute Myeloid Leukemia

2001 • 154 citations

Association between survival after treatment for breast cancer and glutathione S-transferase P1 Ile105Val polymorphism.

2000 • 149 citations

Prognostic value of p53, glutathione S-transferase pi, and thymidylate synthase for neoadjuvant cisplatin-based chemotherapy in head and neck cancer.

1999 • 118 citations

Polymorphisms in GSTP1, GSTM1, and GSTT1 and susceptibility to colorectal cancer.

1999 • 118 citations

Differential Catalytic Efficiency of Allelic Variants of Human GlutathioneS-Transferase Pi in Catalyzing the Glutathione Conjugation of Thiotepa

1999 • 111 citations

Immunohistochemical staining for glutathione S-transferase predicts response to platinum-based chemotherapy in head and neck cancer.

1996 • 83 citations

Low-dose cisplatin and 5-fluorouracil in combination can repress increased gene expression of cellular resistance determinants to themselves.

1999 • 76 citations

Tumor efficacy and bone marrow-sparing properties of TER286, a cytotoxin activated by glutathione S-transferase.

1998 • 76 citations

Overexpression of glutathione S-transferase and elevation of thiol pools in a multidrug-resistant human colon cancer cell line.

1992 • 63 citations

A comparison of two simple hazard ratio estimators based on the logrank test

1992 • 45 citations

Reduced topoisomerase II and elevated α class glutathione S-transferase expression in a multidrug resistant CHO cell line highly cross-resistant to mitomycin C

1992 • 44 citations

Schedule-dependent reversion of cisplatin resistance by 5-fluorouracil in a cisplatin-resistant human lung adenocarcinoma cell line A549DDP.

1999 • 11 citations