Activation of the GABAB receptor inhibits transient lower esophageal sphincter relaxations in dogs

Spasticity, disordered motor control

1980 • 1,097 citations

Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors

1997 • 1,020 citations

Mechanism of gastroesophageal reflux in recumbent asymptomatic human subjects.

1980 • 936 citations

Mechanisms of lower oesophageal sphincter incompetence in patients with symptomatic gastrooesophageal reflux.

1988 • 599 citations

Mechanisms of gastroesophageal reflux in ambulant healthy human subjects

1995 • 322 citations

Provocation of transient lower esophageal sphincter relaxations by meals in patients with symptomatic gastroesophageal reflux

1991 • 219 citations

Multiple GABAB receptors

1993 • 217 citations

Abolition of gas reflux and transient lower esophageal sphincter relaxation by vagal blockade in the dog

1986 • 192 citations

Effect of atropine on the frequency of reflux and transient lower esophageal sphincter relaxation in normal subjects

1995 • 157 citations

Pathophysiology of Gastroesophageal Reflux

1990 • 145 citations

Effect of morphine on gastroesophageal reflux and transient lower esophageal sphincter relaxation

1997 • 143 citations

Motor events underlying gastro-oesophageal reflux in ambulant patients with reflux oesophagitis

1996 • 141 citations

The actions of baclofen on neurones and synaptic transmission in the nucleus tractus solitarii of the rat in vitro.

1992 • 128 citations

Cholecystokinin and nitric oxide in transient lower esophageal sphincter relaxation to gastric distention in dogs

1994 • 122 citations

Cholecystokinin in transient lower oesophageal sphincter relaxation due to gastric distension in humans.

1997 • 100 citations

Plasma and urinary excretion kinetics of oral baclofen in healthy subjects

1989 • 98 citations

Involvement of cholecystokininA receptors in transient lower esophageal sphincter relaxations triggered by gastric distension

1998 • 92 citations

Effect of atropine on gastro-oesophageal reflux and transient lower oesophageal sphincter relaxations in patients with gastro-oesophageal reflux disease

1998 • 77 citations

γ-Aminobutyric acid immunoreactive structures in the nucleus tractus solitarius: a light and electron microscopic study

1992 • 77 citations

Reduction by baclofen of monosynaptic EPSPs in lumbosacral motoneurones of the anaesthetized cat.

1989 • 75 citations

Tonic stimulation of GABAB receptors in the nucleus tractus solitarius modulates the baroreceptor reflex

1992 • 73 citations

Endogenous cholecystokinin enhances postprandial gastroesophageal reflux in humans through extrasphincteric receptors

1998 • 69 citations

Neuronal pathways and transmission to the lower esophageal sphincter of the guinea pig

1998 • 68 citations

GABAB receptors as targets for drug action.

1992 • 66 citations

EFFECT OF GENERAL ANAESTHESIA ON TRANSIENT LOWER OESOPHAGEAL SPHINCTER RELAXATIONS IN THE DOG

1988 • 66 citations

Systemic baclofen stimulates gastric motility and secretion via a central action in the rat

1986 • 65 citations

Does body posture affect the incidence and mechanism of gastro-oesophageal reflux?

1991 • 59 citations

Mechanism of the cardiovascular effects of GABAB receptor activation in the nucleus tractus solitarii of the rat

1990 • 59 citations

Effect of cisapride on postprandial gastro-oesophageal reflux.

1989 • 51 citations

Effect of cholecystokinin on lower oesophageal sphincter pressure and transient lower oesophageal sphincter relaxations in humans.

1995 • 49 citations

Gastric acid and vagus nerve response to GABA agonist baclofen

1985 • 49 citations

Functional GABA_Areceptors on rat vagal afferent neurones

1997 • 48 citations

Sensitive method for the determination of baclofen in plasma by means of solid-phase extraction and liquid chromatography–tandem mass spectrometry

1999 • 45 citations

Modulation of the vagal drive to the intramural cholinergic and non‐cholinergic neurones in the ferret stomach by baclofen.

1987 • 42 citations

Mechanism of inhibition of calcium channels in rat nucleus tractus solitarius by neurotransmitters

1996 • 41 citations

GABAB receptors as potential targets for drugs able to prevent excessive excitatory amino acid transmission in the spinal cord

1998 • 40 citations

μ-Opioid and GABAB receptors modulate different types of Ca2+ currents in rat nodose ganglion neurons

1998 • 40 citations

GABAergic effects on nucleus tractus solitarius neurons receiving gastric vagal inputs.

1998 • 38 citations

Influence of GABAergic mechanisms on baroreceptor inputs to nucleus tractus solitarii of rats

1996 • 27 citations

Eructation of gas through the gastroesophageal sphincter before and after limiting distension of the gastric cardia or infusion of a beta-adrenergic amine in dogs.

1989 • 21 citations

Influence of different intragastric stimuli on triggering of transient lower oesophageal sphincter relaxation in the dog

1999 • 20 citations

Baclofen-induced block of the Hering–Breuer expiratory-promoting reflex in rats

1995 • 18 citations

Comparison of the pharmacokinetics of intravenously administered rac-baclofen and its (-)-(R)- and (+)-(S)-enantiomers in dogs.

1989 • 12 citations

Sterols in cerebrospinal fluid during nitrosourea chemotherapy of human brain tumors

1976 • 8 citations

Effects of an N-methyl-D-aspartate (NMDA) receptor antagonist on transient lower esophageal sphincter relaxations (TLESRs) in the dog

1998 • 7 citations