Intrastriatal Dopamine Injection Induces Apoptosis Through Oxidation-Involved Activation of Transcription Factors AP-1 and NF-κB in Rats

Apoptosis by Death Factor

1997 • 5,038 citations

Activation of Transcription Factor NF-κB Is Suppressed by Curcumin (Diferuloylmethane)

1995 • 1,352 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1997 • 1,229 citations

Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones.

1978 • 1,073 citations

Inhibition of Nuclear Translocation of Transcription Factor NF-κB by a Synthetic Peptide Containing a Cell Membrane-permeable Motif and Nuclear Localization Sequence

1995 • 923 citations

The Generation of Hydrogen Peroxide, Superoxide Radical, and Hydroxyl Radical by 6-Hydroxydopamine, Dialuric Acid, and Related Cytotoxic Agents

1974 • 894 citations

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

1991 • 800 citations

Continuous c-fos expression precedes programmed cell death in vivo

1993 • 784 citations

Neuroprotection by Aspirin and Sodium Salicylate Through Blockade of NF-κB Activation

1996 • 760 citations

DNA Damaging Agents Induce Expression of Fas Ligand and Subsequent Apoptosis in T Lymphocytes via the Activation of NF-κB and AP-1

1998 • 726 citations

Nuclear translocation of NF-κB is increased in dopaminergic neurons of patients with Parkinson disease

1997 • 676 citations

Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections.

1996 • 544 citations

Regulation of the NF-ηB/rel transcription factor and IηB inhibitor system

1993 • 541 citations

Traumatic spinal cord injury induces nuclear factor-kappaB activation.

1998 • 434 citations

IEX -1L, an Apoptosis Inhibitor Involved in NF-κB-Mediated Cell Survival

1998 • 417 citations

Constitutive NF-kB Activity in Neurons

1994 • 400 citations

Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin

1998 • 399 citations

Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells.

1991 • 381 citations

Traumatic Spinal Cord Injury Induces Nuclear Factor-κB Activation

1998 • 379 citations

Phosphorylation of c-Jun Is Necessary for Apoptosis Induced by Survival Signal Withdrawal in Cerebellar Granule Neurons

1998 • 365 citations

The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo

1997 • 350 citations

Lasting N-Terminal Phosphorylation of c-Jun and Activation of c-Jun N-Terminal Kinases after Neuronal Injury

1998 • 330 citations

Dopamine Induces Apoptosis through an Oxidation-involved SAPK/JNK Activation Pathway

1998 • 310 citations

Constitutive NF-kappa B activity in neurons.

1994 • 304 citations

Role of dopamine in the neurotoxic effects of methamphetamine.

1985 • 299 citations

Role of the Jun Kinase Pathway in the Regulation of c-Jun Expression and Apoptosis in Sympathetic Neurons

1998 • 284 citations

Substantia nigra lesion protects against ischemic damage in the striatum

1987 • 267 citations

Dopamine induces apoptosis-like cell death in cultured chick sympathetic neurons — A possible novel pathogenetic mechanism in Parkinson's disease

1994 • 222 citations

High Constitutive NF-κB Activity Mediates Resistance to Oxidative Stress in Neuronal Cells

1998 • 189 citations

Nuclear Factor-κB Contributes to Excitotoxin-Induced Apoptosis in Rat Striatum

1998 • 167 citations

A simple and repid method for detection of apoptosis in human cells

1992 • 163 citations

The apparent autoxidation rate of catechols in dopamine-rich regions of human brains increases with the degree of depigmentation of substantia nigra

1989 • 162 citations

Glutamate, But Not Dopamine, Stimulates Stress-Activated Protein Kinase and AP-1-Mediated Transcription in Striatal Neurons

1997 • 159 citations

Increase in Extracellular Dopamine in the Striatum During Cerebral Ischemia: A Study Utilizing Cerebral Microdialysis

1988 • 119 citations

Drug-Induced Neuroprotection From Global Ischemia Is Associated With Prevention of Persistent but Not Transient Activation of Nuclear Factor-κB in Rats

1998 • 113 citations

Inhibition of Glutamate Transport in Synaptosomes by Dopamine Oxidation and Reactive Oxygen Species

1997 • 110 citations

D2 Dopamine Receptors Stimulate Mitogenesis Through Pertussis Toxin‐Sensitive G Proteins and Ras‐Involved ERK and SAP/JNK Pathways in Rat C6‐D2L Glioma Cells

1998 • 107 citations

D₁Dopamine Receptor Agonists Mediate Activation of p38 Mitogen-Activated Protein Kinase and c-Jun Amino-Terminal Kinase by a Protein Kinase A-Dependent Mechanism in SK-N-MC Human Neuroblastoma Cells

1998 • 85 citations

Striatal Protection Induced by Lesioning the Substantia Nigra of Rats Subjected to Focal Ischemia

1992 • 84 citations

Effects of Hypoxia on the Activity of the Dopaminergic Neuron System in the Rat Striatum as Studied by In Vivo Brain Microdialysis

1991 • 72 citations

Apoptosis in neurodegenerative disorders

1997 • 72 citations

Selective Role of Glutathione in Protecting Human Neuronal Cells From Dopamine-induced Apoptosis

1996 • 70 citations

Dopamine induces apoptosis in cultured rat striatal neurons; possible mechanism of D2-dopamine receptor neuron loss during aging

1997 • 63 citations

Intrastriatal injection of dopamine results in DNA damage and apoptosis in rats

1998 • 52 citations

Dopaminergic modulation of excitotoxicity in rat striatum: Evidence from nigrostriatal lesions

1991 • 51 citations

Dopamine induces apoptosis in cultured rat striatal neurons; possible mechanism of D2‐dopamine receptor neuron loss during aging

1997 • 3 citations