A histologically distinctive interstitial pneumonia induced by overexpression of the interleukin 6, transforming growth factor beta 1, or platelet-derived growth factor B gene.

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy.

1994 • 1,599 citations

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

1989 • 1,411 citations

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1988 • 1,351 citations

Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6.

1993 • 827 citations

Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis.

1991 • 794 citations

TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop

1990 • 756 citations

A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-β

1988 • 620 citations

Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney.

1993 • 525 citations

Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice.

1995 • 504 citations

Exaggerated Spontaneous Release of Platelet-Derived Growth Factor by Alveolar Macrophages from Patients with Idiopathic Pulmonary Fibrosis

1987 • 420 citations

The effect of transforming growth factor-beta on cell proliferation and collagen formation by lung fibroblasts.

1987 • 399 citations

Enhanced IL-1 beta and tumor necrosis factor-alpha release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposure.

1993 • 329 citations

Transforming growth factor beta reverses the glucocorticoid-induced wound-healing deficit in rats: possible regulation in macrophages by platelet-derived growth factor.

1989 • 308 citations

Establishment of an interleukin 6 (IL 6)/B cell stimulatory factor 2‐dependent cell line and preparation of anti‐IL 6 monoclonal antibodies

1988 • 308 citations

Molecular cloning of a murine IL-6 receptor-associated signal transducer, gp130, and its regulated expression in vivo.

1992 • 284 citations

Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice.

1993 • 252 citations

Increased expression of the interleukin-8 gene by alveolar macrophages in idiopathic pulmonary fibrosis. A potential mechanism for the recruitment and activation of neutrophils in lung fibrosis.

1991 • 249 citations

Lymphocytic Interstitial Pneumonitis

1978 • 207 citations

Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice.

1994 • 186 citations

Characterization of IL-6 receptor expression by monoclonal and polyclonal antibodies.

1989 • 179 citations

Construction of nondefective adenovirus type 5 bearing a 2.8-kilobase hepatitis B virus DNA near the right end of its genome

1985 • 144 citations

Human Alveolar Macrophage Cytokine Release in Response to in Vitro and in Vivo Asbestos Exposure

1993 • 83 citations

Direct injection of hepatitis B virus DNA into liver induced hepatitis in adult rats.

1991 • 60 citations