Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice.

Epidermal Growth Factor

1979 • 2,964 citations

Epidermal growth factor.

1990 • 1,645 citations

Human transforming growth factor-α: Precursor structure and expression in E. coli

1984 • 888 citations

Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast

1990 • 753 citations

Introns increase transcriptional efficiency in transgenic mice.

1988 • 733 citations

TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

1990 • 714 citations

Rat Transforming Growth Factor Type 1: Structure and Relation to Epidermal Growth Factor

1984 • 666 citations

Human epidermal growth factor: isolation and chemical and biological properties.

1975 • 499 citations

Induction of transforming growth factor-α in activated human alveolar macrophages

1988 • 359 citations

Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury.

1992 • 321 citations

Transcriptional Elements from the Human SP-C Gene Direct Expression in the Primordial Respiratory Epithelium of Transgenic Mice

1993 • 299 citations

Molecular mechanism of mitogen action: Processing of receptor induced by epidermal growth factor

1978 • 271 citations

Human transforming growth factors induce tyrosine phosphorylation of EGF receptors

1981 • 244 citations

Effect of Epidermal Growth Factor on Lung Maturation in Fetal Rabbits

1979 • 207 citations

Epigenetic role of epidermal growth factor expression and signalling in embryonic mouse lung morphogenesis

1992 • 189 citations

Differential effects of epidermal growth factor and transforming growth factor-beta on synthesis of Mr = 35,000 surfactant-associated protein in fetal lung.

1987 • 170 citations

Effects of epidermal growth factor on lung maturation in fetal lambs.

1980 • 168 citations

Developmental Expression of Rat Transforming Growth Factor-α mRNA

1985 • 147 citations

Simian virus 40 large T antigen directed by transcriptional elements of the human surfactant protein C gene produces pulmonary adenocarcinomas in transgenic mice.

1992 • 120 citations

Structure and expression of the pulmonary surfactant protein SP-C gene in the mouse.

1990 • 108 citations

Internalization and processing of the EGF receptor in the induction of DNA synthesis in cultured fibroblasts: The endocytic activation hypothesis

1979 • 100 citations

Localization of epidermal growth factor precursor in tooth and lung during embryonic mouse development

1989 • 98 citations

EGF and TGF alpha influence in vitro lung development by the induction of matrix-degrading metalloproteinases.

1991 • 96 citations

Immunocytochemical localization of epidermal growth factor in the developing human respiratory system and in acute and chronic lung disease in the neonate.

1989 • 84 citations

Risk Factors for the Degradation of Lung Elastic Fibers in the Ventilated Neonate: Implications for Impaired Lung Development in Bronchopulmonary Dysplasia

1992 • 81 citations

Human cystic fibrosis transmembrane conductance regulator directed to respiratory epithelial cells of transgenic mice

1992 • 78 citations

Immunohistochemical Localization of Epidermal Growth Factor and Acidic and Basic Fibroblast Growth Factors in Postnatal Developing and Adult Rat Lungs

1992 • 74 citations

Acceleration of alveolar type II cell differentiation in fetal rhesus monkey lung by administration of EGF

1992 • 72 citations

Immunohistochemical localisation and developmental aspects of epidermal growth factor in the rat

1988 • 50 citations

Expression of Transforming Growth Factor-α in Mid-gestation Human Fetal Lung

1993 • 38 citations

Ontogeny of Epidermal Growth Factor Receptor/Kinase and of Lipocortin-1 in the Ovine Lung

1989 • 32 citations

Epidermal growth factor in the rat lung

1991 • 29 citations

Transforming Growth Factor-α Gene Expression in Late-Gestation Fetal Rat Lung

1992 • 29 citations