Synergistic Cytokine-Induced Nitric Oxide Production in Human Alveolar Epithelial Cells

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

1987 • 5,027 citations

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.

1994 • 2,216 citations

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

1985 • 1,596 citations

Measurement of Cell Growth in Tissue Culture with a Phenol Reagent (Folin-Ciocalteau)

1956 • 945 citations

Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species.

1993 • 785 citations

Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells.

1994 • 595 citations

Role of interferon regulatory factor 1 in induction of nitric oxide synthase.

1994 • 477 citations

Multiple NF-κB Enhancer Elements Regulate Cytokine Induction of the Human Inducible Nitric Oxide Synthase Gene

1998 • 408 citations

Nitric oxide is the endogenous neurotransmitter of bronchodilator nerves in humans

1992 • 396 citations

Expression of Inducible Nitric Oxide in Human Lung Epithelial Cells

1994 • 346 citations

Cytokine-mediated Transcriptional Induction of the Human Inducible Nitric Oxide Synthase Gene Requires Both Activator Protein 1 and Nuclear Factor κB-binding Sites

1998 • 309 citations

Inhalation of Nitric Oxide Modulates Adult Human Bronchial Tone

1993 • 296 citations

Interferon gamma and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators.

1997 • 186 citations

Interactions between Respiratory Epithelial Cells and Cytokines: Relationships to Lung Inflammation

1994 • 180 citations

Analysis of the Cytokine-Stimulated Human Inducible Nitric Oxide Synthase (iNOS) Gene: Characterization of Differences between Human and Mouse iNOS Promoters

1998 • 165 citations

L-Arginine-dependent production of nitrogen oxides by rat pulmonary macrophages

1991 • 123 citations

Potentiation of tumor necrosis factor-alpha-mediated cytotoxicity of mast cells by their production of nitric oxide.

1991 • 100 citations

Pulmonary alveolar epithelial inducible NO synthase gene expression: regulation by inflammatory mediators

1995 • 95 citations

Induction of L‐arginine transport and nitric oxide synthase in vascular smooth muscle cells: synergistic actions of pro‐inflammatory cytokines and bacterial lipopolysaccharide

1995 • 68 citations

Characterization and Functional Analysis of the Human Inducible Nitric Oxide Synthase Gene Promoter

1996 • 65 citations

Differential Regulation of <scp>l</scp> -Arginine Transport and Nitric Oxide Production by Vascular Smooth Muscle and Endothelium

1996 • 61 citations

Differential regulation of L-arginine transport and inducible NOS in cultured vascular smooth muscle cells

1995 • 47 citations

Unique patterns of regulation of nitric oxide production in fibroblasts

1995 • 45 citations

Hepatic inducible nitric oxide synthase: regulation and function

1995 • 26 citations