L-Arginine-dependent production of nitrogen oxides by rat pulmonary macrophages

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

1988 • 2,865 citations

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

1988 • 1,622 citations

Macrophage Cytotoxicity: Role for L-Arginine Deiminase and Imino Nitrogen Oxidation to Nitrite

1987 • 1,533 citations

Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide.

1985 • 1,146 citations

Macrophages and Polymorphonuclear Neutrophils in Lung Defense and Injury

1990 • 1,091 citations

Induction of nitrite/nitrate synthesis in murine macrophages by BCG infection, lymphokines, or interferon-gamma.

1987 • 722 citations

Macrophage Oxidation of L-Arginine to Nitric Oxide, Nitrite, and Nitrate

1989 • 681 citations

Interferon‐γ and tumor necrosis factor induce the L‐arginine‐dependent cytotoxic effector mechanism in murine macrophages^*

1988 • 511 citations

Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide.

1989 • 464 citations

Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages

1990 • 455 citations

Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells.

1989 • 405 citations

Differential induction of brain, lung and liver nitric oxide synthase by endotoxin in the rat

1990 • 399 citations

Arginine is a physiological precursor of endothelium-derived nitric oxide

1988 • 392 citations

Anti-inflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat

1990 • 389 citations

Temporal expression of different pathways of 1-arginine metabolism in healing wounds.

1990 • 351 citations

An L-arginine-dependent mechanism mediates kupffer cell inhibition of hepatocyte protein synthesis in vitro

1989 • 325 citations

Characterization of the Effects of Endotoxin on Macrophage Tumor Cell Killing

1978 • 298 citations

Macrophage and endothelial cell nitric oxide synthesis: Cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine

1990 • 277 citations

IFN-γ-activated macrophages: Detection by electron paramagnetic resonance of complexes between L-Arginine-derived nitric oxide and non-heme iron proteins

1990 • 185 citations

L-arginine-dependent reactive nitrogen intermediates as mediators of tumor cell killing by activated macrophages.

1990 • 155 citations

Regulation of macrophage physiology by L-arginine: role of the oxidative L-arginine deiminase pathway.

1989 • 128 citations

The Effect of Endotoxin Inhalation on Airway Responsiveness and Cellular Influx in Rats

1990 • 96 citations

Chemiluminescent response to pathogenic organisms: normal human polymorphonuclear leukocytes

1984 • 80 citations

Carrageenan-stimulated release of arachidonic acid and of lactate dehydrogenase from rat pleural cells

1987 • 27 citations