Degradation of c-Fos by the 26S Proteasome Is Accelerated by c-Jun and Multiple Protein Kinases

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1990 • 3,896 citations

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1991 • 3,396 citations

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis

1986 • 2,566 citations

Cyclin is degraded by the ubiquitin pathway

1991 • 2,355 citations

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1993 • 2,329 citations

The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

1994 • 2,124 citations

The ubiquitin-proteasome proteolytic pathway

1994 • 1,778 citations

THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION

1992 • 1,402 citations

The regulation of transcription by phosphorylation

1992 • 1,316 citations

The MAP kinase cascade is essential for diverse signal transduction pathways

1993 • 1,091 citations

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain

1994 • 930 citations

Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination

1992 • 780 citations

Proteolysis, proteasomes and antigen presentation

1992 • 576 citations

Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene

1990 • 522 citations

High efficiency gene transfer into mammalian cells

1984 • 498 citations

The multicatalytic and 26 S proteases.

1993 • 476 citations

The N-end rule

1992 • 464 citations

Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain

1988 • 455 citations

The mechanism and functions of ATP‐dependent proteases in bacterial and animal cells

1992 • 450 citations

In vitro effects on microtubule dynamics of purified Xenopus M phase-activated MAP kinase

1991 • 422 citations

The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation.

1992 • 414 citations

Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATα2 repressor

1993 • 397 citations

Nuclear Proto-Oncogenes Fos and Jun

1990 • 392 citations

Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity

1992 • 387 citations

Control of transcription factors by signal transduction pathways: the beginning of the end

1992 • 360 citations

Degradation of nuclear oncoproteins by the ubiquitin system in vitro.

1991 • 345 citations

Expression of different Jun and Fos proteins during the G0-to-G1 transition in mouse fibroblasts: in vitro and in vivo associations.

1991 • 309 citations

p34^Cdc28-Mediated Control of Cln3 Cyclin Degradation

1995 • 293 citations

Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2.

1994 • 235 citations

Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway.

1995 • 213 citations

Regulation of V(D)J Recombination Activator Protein RAG-2 by Phosphorylation

1993 • 209 citations

A synthetic peptide substrate specific for casein kinase II.

1985 • 202 citations

The Oncogene Handbook

1988 • 181 citations

[34] Casein kinase II

1983 • 172 citations

The ‘second-codon rule’ and autophosphorylation govern the stability and activity of Mos during the meiotic cell cycle in Xenopus oocytes.

1992 • 147 citations

Possible mechanism of nuclear translocation of proteasomes

1990 • 132 citations

Degradation of Mos by the N-terminal proline (Pro2)-dependent ubiquitin pathway on fertilization of Xenopus eggs: possible significance of natural selection for Pro2 in Mos.

1993 • 127 citations

Destruction of Xenopus cyclins A and B2, but not B1, requires binding to p34cdc2.

1994 • 111 citations

Targeted Degradation of c-Fos, But Not v-Fos, by a Phosphorylation-Dependent Signal on c-Jun

1992 • 110 citations

Proteasomes: protein and gene structures.

1992 • 108 citations

Association of p34cdc2/cyclin B complex with microtubules in starfish oocytes

1993 • 87 citations

Purification and Characterization of the 26S Proteasome Complex Catalyzing ATP-Dependent Breakdown of Ubiquitin-Ligated Prot from Rat Liver1

1993 • 85 citations

Phosphorylation of glycogen synthase by cyclic AMP-independent casein kinase-2 from rabbit skeletal muscle.

1982 • 64 citations

Mos is degraded by the 26S proteasome in a ubiquitin‐dependent fashion

1993 • 56 citations

Proteasome and cell cycle

1993 • 50 citations

Complete reconstitution of conjugation and subsequent degradation of the tumor suppressor protein p53 by purified components of the ubiquitin proteolytic system

1994 • 39 citations

Improved method for preparation of ubiquitin‐ligated lysozyme as substrate of ATP‐dependent proteolysis

1991 • 29 citations