Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). II. Comparison of hybridomas derived by lipopolysaccharide stimulation and secondary protein immunization.

AN ANALYSIS OF THE SEQUENCES OF THE VARIABLE REGIONS OF BENCE JONES PROTEINS AND MYELOMA LIGHT CHAINS AND THEIR IMPLICATIONS FOR ANTIBODY COMPLEMENTARITY

1970 • 1,308 citations

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a γ2a variable region

1981 • 677 citations

Differential Agglutination of Normal and Sensitized Sheep Erythrocytes by Sera of Patients with Rheumatoid Arthritis

1948 • 563 citations

The immunoglobulin heavy chain variable region (Igh‐V) locus in the mouse. I. One hundred Igh‐V genes comprise seven families of homologous genes

1984 • 537 citations

Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.

1979 • 472 citations

Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments.

1982 • 411 citations

Structural Basis of Antibody Function

1983 • 371 citations

Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin.

1985 • 319 citations

Classification of mouse VK groups based on the partial amino acid sequence to the first invariant tryptophan: Impact of 14 new sequences from IgG myeloma proteins

1982 • 156 citations

Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells.

1986 • 139 citations

Increased frequency of rheumatoid factor precursor B lymphocytes after immunization of normal adults with tetanus toxoid.

1983 • 137 citations

Induction of rheumatoid antibodies in the mouse. Regulated production of autoantibody in the secondary humoral response.

1983 • 135 citations

Rheumatoid factor (RF) production during anamnestic immune responses in the mouse. III. Activation of RF precursor cells is induced by their interaction with immune complexes and carrier-specific helper T cells.

1985 • 125 citations

Immune complexes can trigger specific, T cell-dependent, autoanti-IgG antibody production in mice.

1985 • 123 citations

V_H‐gene expression in murine lipopolysaccharide blasts distributes over the nine known V_H‐gene groups and may be random

1985 • 122 citations

Influence of Clonal Selection on the Expression of Immunoglobulin Variable Region Genes

1984 • 120 citations

A speculative view of the multicomponent nature of T cell antigen recognition

1986 • 117 citations

Genetic Control of Antibody Variable Regions

1977 • 112 citations

Sequences of the joining region genes for immunoglobulin heavy chains and their role in generation of antibody diversity.

1981 • 109 citations

Rheumatoid Factor-Like Immunoglobulin M Protects Previously Uninfected Rat Pups and Dams from Trypanosoma lewisi

1981 • 73 citations

Rheumatoid factors and secondary immune responses in the mouse II. Incidence, kinetics and induction mechanisms

1983 • 71 citations

Structural and functional implications of a restricted antibody response to a defined antigenic region on the influenza virus hemagglutinin.

1986 • 69 citations

Characterization of human rheumatoid factors with seven antiidiotypes induced by synthetic hypervariable region peptides.

1985 • 64 citations

Site-directed mutagenesis of an invariant amino acid residue at the variable-diversity segments junction of an antibody.

1986 • 55 citations

Monoclonal anti-IgG autoantibodies derived from lipopolysaccharide-activated spleen cells of 129/Sv mice

1982 • 51 citations

Evolution of a multigene family of V kappa germ line genes.

1984 • 32 citations

Evidence for 65 electrophoretically distinct groups of light chains in BALB/c and NZB myelomas

1984 • 22 citations

Determinants recognized by murine rheumatoid factors: molecular localization using a panel of mouse myeloma variant immunoglobulins.

1983 • 15 citations

Expression of kappa chains of the Vκ21 group in Mus musculus and related species

1981 • 12 citations

Structure and genetic control of Vk-1 light chains

1984 • 11 citations