Analysis of Human Papillomavirus Type 16 (HPV16) DNA Load and Physical State for Identification of HPV16-Infected Women with High-Grade Lesions or Cervical Carcinoma

Human papillomavirus is a necessary cause of invasive cervical cancer worldwide

1999 • 8,737 citations

Epidemiologic Classification of Human Papillomavirus Types Associated with Cervical Cancer

2003 • 6,072 citations

Prevalence of Human Papillomavirus in Cervical Cancer: a Worldwide Perspective

1995 • 3,371 citations

Classification of papillomaviruses

2004 • 3,098 citations

Global cancer statistics in the year 2000

2001 • 2,471 citations

Human papillomavirus type distribution in invasive cervical cancer and high‐grade cervical lesions: A meta‐analysis update

2007 • 1,654 citations

NATURAL HISTORY OF CERVICAL INTRAEPITHELIAL NEOPLASIA

1967 • 1,370 citations

Against which human papillomavirus types shall we vaccinate and screen? the international perspective

2004 • 1,099 citations

The Elevated 10-Year Risk of Cervical Precancer and Cancer in Women With Human Papillomavirus (HPV) Type 16 or 18 and the Possible Utility of Type-Specific HPV Testing in Clinical Practice

2005 • 1,038 citations

Mechanisms of Human Papillomavirus-Induced Oncogenesis

2004 • 1,002 citations

The papillomavirus life cycle

2005 • 819 citations

Natural history of cervical human papillomavirus infection in young women: a longitudinal cohort study

2001 • 814 citations

Persistent Genital Human Papillomavirus Infection as a Risk Factor for Persistent Cervical Dysplasia

1995 • 811 citations

Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines

1987 • 760 citations

Estimates of cancer incidence and mortality in Europe in 1995

2002 • 695 citations

Epidemiology of Acquisition and Clearance of Cervical Human Papillomavirus Infection in Women from a High‐Risk Area for Cervical Cancer

1999 • 668 citations

Type-Specific Persistence of Human Papillomavirus DNA before the Development of Invasive Cervical Cancer

1999 • 495 citations

Natural history of cervical squamous intraepithelial lesions: a meta-analysis*1

1998 • 430 citations

Regression of low-grade squamous intra-epithelial lesions in young women

2004 • 420 citations

Persistence and load of high‐risk HPV are predictors for development of high‐grade cervical lesions: A longitudinal French cohort study

2003 • 416 citations

Integrated Human Papillomavirus Type 16 Is Frequently Found in Cervical Cancer Precursors as Demonstrated by a Novel Quantitative Real-Time PCR Technique

2002 • 389 citations

Viral load of human papilloma virus 16 as a determinant for development of cervical carcinoma in situ: a nested case-control study

2000 • 371 citations

Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity.

1992 • 315 citations

Human papillomavirus 16 load in normal and abnormal cervical scrapes: An indicator of CIN II/III and viral clearance

2002 • 262 citations

Human Papillomavirus Type 16 Integration in Cervical Carcinoma In Situ and in Invasive Cervical Cancer

2006 • 242 citations

Papillomavirus polypeptides E6 and E7 are zinc-binding proteins

1989 • 239 citations

Physical state and expression of HPV DNA in benign and dysplastic cervical tissue: different levels of viral integration are correlated with lesion grade

2004 • 196 citations

Nucleotide sequences and further characterization of human papillomavirus DNA present in the CaSki, SiHa and HeLa cervical carcinoma cell lines.

1999 • 195 citations

High load for most high risk human papillomavirus genotypes is associated with prevalent cervical cancer precursors but only HPV16 load predicts the development of incident disease

2007 • 163 citations

TaqMan PCR-based Gene Dosage Assay for Predictive Testing in Individuals from a Cancer Family with INK4 Locus Haploinsufficiency

1999 • 145 citations

A prospective study showing long-term infection with human papillomavirus 16 before the development of cervical carcinoma in situ.

2000 • 136 citations

Disruption of the E1 and E2 Reading Frames of HPV 16 in Cervical Carcinoma Is Associated with Poor Prognosis

1998 • 131 citations

Type distribution, viral load and integration status of high-risk human papillomaviruses in pre-stages of cervical cancer (CIN)

2005 • 126 citations

Determinants of human papillomavirus load among women with histological cervical intraepithelial neoplasia 3: dominant impact of surrounding low-grade lesions.

2003 • 119 citations

Early integration of high copy HPV16 detectable in women with normal and low grade cervical cytology and histology

2006 • 118 citations

Viral DNA load, physical status and E2/E6 ratio as markers to grade HPV16 positive women for high-grade cervical lesions

2007 • 117 citations

Relationships of Human Papillomavirus Type, Qualitative Viral Load, and Age with Cytologic Abnormality

2006 • 116 citations

Human papillomavirus (HPV) genotype distribution in invasive cervical cancers in France: EDITH study

2007 • 102 citations

Rapid and Sensitive Detection of Physical Status of Human Papillomavirus Type 16 DNA by Quantitative Real-Time PCR

2002 • 92 citations

Dynamics of HPV16 DNA load reflect the natural history of cervical HPV-associated lesions

2005 • 77 citations

HPV prevalence, viral load and physical state of HPV‐16 in cervical smears of patients with different grades of CIN

2007 • 74 citations

Human Papillomavirus Quantification in Urine and Cervical Samples by Using the Mx4000 and LightCycler General Real-Time PCR Systems

2007 • 74 citations

Physical status of the E2 human papilloma virus 16 viral gene in cervical preneoplastic and neoplastic lesions

2001 • 74 citations

Distribution and viral load of type specific HPVs in different cervical lesions as detected by PCR-ELISA

2001 • 71 citations

Determination of HPV type 16 and 18 viral load in cervical smears of women referred to colposcopy

2006 • 71 citations

Human papillomavirus genotype distribution in high grade cervical lesions (CIN 2/3) in France: EDITH study

2007 • 65 citations

Study of viral integration of HPV-16 in young patients with LSIL

2003 • 63 citations

Association between Quantitative High-Risk Human Papillomavirus DNA Load and Cervical Intraepithelial Neoplasm Risk

2005 • 59 citations

High risk HPV load estimated by Hybrid Capture II® correlates with HPV16 load measured by real-time PCR in cervical smears of HPV16-infected women

2004 • 46 citations

Comparison Between In Situ Hybridization and Real-time PCR Technique as a Means of Detecting the Integrated Form of Human Papillomavirus 16 in Cervical Neoplasia

2005 • 42 citations

Human Papillomavirus Type 16 Status in Cervical Carcinoma Cell DNA Assayed by Multiplex PCR

2003 • 41 citations

Determination of Human Papillomavirus (HPV) Load and Type in High-Grade Cervical Lesions Surgically Resected from HIV-Infected Women during Follow-up of HPV Infection

2005 • 38 citations

ASCUS : état des lieux

2006 • 12 citations

Preventing cervical cancer: the role of the Bethesda system.

1995 • 11 citations

Deleted Work

1955 • 0 citations