The Search for Antibodies with Molecular Uniformity

The hydrolysis of rabbit γ-globulin and antibodies with crystalline papain

1959 • 2,294 citations

Chemical Coupling of Peptides and Proteins to Polysaccharides by Means of Cyanogen Halides

1967 • 2,172 citations

Variations in Affinities of Antibodies during the Immune Response^*

1964 • 1,078 citations

Chemical Coupling of Proteins to Agarose

1967 • 981 citations

Current Knowledge of Type-Specific M Antigens of Group A Streptococci

1962 • 793 citations

Individual Antigenic Specificity of Isolated Antibodies

1963 • 494 citations

STUDIES ON STRUCTURAL UNITS OF THE γ-GLOBULINS

1961 • 463 citations

THE ARRANGEMENT OF THE PEPTIDE CHAINS IN γ-GLOBULIN

1963 • 462 citations

STUDIES ON HUMAN ANTIBODIES

1968 • 435 citations

HUMAN IMMUNITY TO THE MENINGOCOCCUS

1969 • 409 citations

Electrophoretic Heterogeneity of Polypeptide Chains of Specific Antibodies

1966 • 358 citations

The Antibody Problem

1969 • 347 citations

Mouse myeloma proteins with antihapten antibody activity. Protein produced by plasma cell tumor MOPC-315

1968 • 339 citations

AGGLUTINATION OF ERYTHROCYTESCOATED WITH “INCOMPLETE” ANTI-RH BY CERTAIN RHEUMATOID ARTHRITIC SERA AND SOME OTHER SERA

1956 • 322 citations

Heterogeneity and Average Combining Constants of Antibodies from Individual Rabbits

1958 • 312 citations

Induction of Plasma-Cell Neoplasms in Strain BALB/c Mice with Mineral Oil and Mineral Oil Adjuvants

1962 • 311 citations

Light Chain Evolution

1967 • 263 citations

Antigenic Specificities Related to the Cold Agglutinin Activity of Gamma M Globulins

1968 • 243 citations

Structure and Biological Activity of Immunoglobulins

1964 • 235 citations

Purification of antibodies with immunoadsorbents prepared using bromoacetyl cellulose

1967 • 230 citations

STUDIES ON THE CHEMICAL STRUCTURE OF THE STREPTOCOCCAL CELL WALL

1961 • 227 citations

Mechanism of Antibody Diversity: Germ Line Basis for Variability

1970 • 222 citations

Antibody Active Sites and Immunoglobulin Molecules

1966 • 221 citations

CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS

1931 • 211 citations

Hydrolysis of phenylthiohydantoins of amino acids

1964 • 200 citations

Pneumococcal C-substance, a ribitol teichoic acid containing choline phosphate

1968 • 184 citations

VARIATION IN THE GROUP-SPECIFIC CARBOHYDRATE OF GROUP A STREPTOCOCCI

1956 • 172 citations

IDIOTYPY OF RABBIT ANTIBODIES

1969 • 168 citations

Structure and biological properties of immunoglobulins

1967 • 166 citations

Formation of specific antibodies and γ-globulin in vitro. A study of the synthetic ability of various tissues from rabbits immunized by different methods

1958 • 152 citations

Variation in the N-terminal sequence of heavy chains of immunoglobulin G from rabbits of different allotype

1969 • 150 citations

CHARACTERISTICS OF STREPTOCOCCAL GROUP-SPECIFIC ANTIBODY ISOLATED FROM HYPERIMMUNE RABBITS

1966 • 129 citations

INDIVIDUAL ANTIGENIC SPECIFICITY OF MYELOMA PROTEINS

1965 • 128 citations

Phylogeny of Immunoglobulins

1969 • 128 citations

Studies of a Waldenstrom-type macroglobulin with rheumatoid factor properties.

1961 • 123 citations

Characterization of the antibody to the C-carbohydrate produced by a transplantable mouse plasmacytoma

1969 • 122 citations

IDIOTYPY OF RABBIT ANTIBODIES

1969 • 119 citations

Three IgA Myeloma Immunoglobulins from the BALB/c Mouse: Precipitation with Pneumococcal C Polysaccharide

1968 • 111 citations

THE INDIVIDUAL ANTIGENIC SPECIFICITY OF ANTIBODIES TO STREPTOCOCCAL CARBOHYDRATES

1968 • 105 citations

STUDIES ON THE CHEMICAL STRUCTURE OF THE STREPTOCOCCAL CELL WALL

1962 • 104 citations

The Development of a Myeloma-Like Condition in Mink with Aleutian Disease

1965 • 104 citations

PROTEINS IN MULTIPLE MYELOMA

1953 • 104 citations

Immunochemistry and genetics of a "new" allotypic specificity Ae14 of rabbit gamma-G immunoglobulins: recombination in somatic cells.

1969 • 103 citations

CHARACTERIZATION OF LAMPREY FIBRINOPEPTIDES

1965 • 102 citations

Mouse Myelomas producing Precipitating Antibody to Nucleic Acid Bases and/or Nitrophenyl Derivatives

1968 • 102 citations

Genetic regulation of immunoglobulin synthesis

1966 • 101 citations

Myeloma proteins and antibodies

1969 • 97 citations

RABBIT ANTIBODIES TO STREPTOCOCCAL CARBOHYDRATES

1969 • 93 citations

A Myeloma Protein with Antibody Activity

1967 • 89 citations

QUANTITATIVE INVESTIGATIONS OF IDIOTYPIC ANTIBODIES

1969 • 87 citations

Structural and Immunological Studies on the Pneumococcal C Polysaccharide

1967 • 84 citations

SPECIFIC FRACTIONATION OF A POPULATION OF ANTIDEXTRAN MOLECULES WITH COMBINING SITES OF VARIOUS SIZES

1962 • 83 citations

Molecular determinants of the A11 and A12 allotypic specificities in rabbit immunoglobulin

1969 • 83 citations

SEPARATION OF TEICHOIC ACID OF STAPHYLOCOCCUS AUREUS INTO TWO IMMUNOLOGICALLY DISTINCT SPECIFIC POLYSACCHARIDES WITH α- AND ß-N-ACETYLGLUCOSAMINYL LINKAGES RESPECTIVELY

1964 • 83 citations

Immunochemistry and Genetics of a “New” Allotypic Specificity Ae14 of Rabbit γG Immunoglobulins: Recombination in Somatic Cells

1969 • 79 citations

Heterogenity of γ-Globulins

1963 • 77 citations

FURTHER STUDIES ON THE CHEMICAL BASIS FOR SEROLOGICAL SPECIFICITY OF GROUP A STREPTOCOCCAL CARBOHYDRATE

1958 • 75 citations

IMMUNOLOGICAL ANALYSIS OF RABBIT ANTI-ANTIBODY SYSTEMS

1968 • 73 citations

Genetic Markers of the Heavy Chain Subgroups of Human G Globulin

1967 • 61 citations

A Chromosome Region for Gamma2a and Beta2A Globulin H Chain Isoantigens in the Mouse

1964 • 60 citations

Antibodies to Type III and Type VIII Pneumococcal Polysaccharides: Evidence for Restricted Structural Heterogeneity in Hyperimmunized Rabbits

1970 • 60 citations

Studies on blood group substances

1969 • 58 citations

Association of allotypic specificities of group a with allotypic specificities A11 and A12 in rabbit immunoglobulin

1970 • 58 citations

INDUCTION OF RABBIT ANTIBODY WITH MOLECULAR UNIFORMITY AFTER IMMUNIZATION WITH GROUP C STREPTOCOCCI

1970 • 57 citations

STUDIES ON HUMAN ANTIBODIES

1964 • 56 citations

Modifications in the Heterogeneity of the Antibody Response

1967 • 55 citations

Location of Specificity and Allotypic Amino Acid Residues in Antibody Fd Fragments

1967 • 52 citations

Formation of antibody by isolated perfused lungs of immunized rabbits. The use of [14C]amino acids to study the dynamics of antibody secretion

1958 • 48 citations

Immunoglobulins

1966 • 48 citations

THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS

1928 • 47 citations

ALLOTYPE EXCLUSION IN UNIFORM RABBIT ANTIBODY TO STREPTOCOCCAL CARBOHYDRATE

1970 • 45 citations

Cell Wall Antigens of Gram-Positive Bacteria

1964 • 44 citations

The immune response to a simple antigenic determinant.

1966 • 43 citations

Immunochemistry

1968 • 43 citations

The use of [14C]amino acids to study sites and rates of antibody synthesis in living hyperimmune rabbits

1958 • 42 citations

Gm Characters of M‐components

1961 • 42 citations

THE EMERGENCE OF ANTIBODIES WITH EITHER IDENTICAL OR UNRELATED INDIVIDUAL ANTIGENIC SPECIFICITY DURING REPEATED IMMUNIZATIONS WITH STREPTOCOCCAL VACCINES

1970 • 41 citations

A carbohydrate-containing mouse light chain-protein

1966 • 41 citations

The generation of antihapten antibodies with electrophoretically homogeneous L chains.

1968 • 40 citations

SUPPRESSION OF HEAVY AND LIGHT CHAIN ALLOTYPIC EXPRESSION IN HOMOZYGOUS RABBITS THROUGH EMBRYO TRANSFER

1969 • 40 citations

STUDIES ON HUMAN ANTIBODIES

1969 • 39 citations

Electrophoretic Analysis of Polypeptide Chains Isolated from Antibodies in the Serum of Immunized Rabbits

1967 • 37 citations

The homogeneous-γ-G-immunoglobulin produced by mouse plasmacytoma 5563 and its subsequent heterogeneity in serum

1967 • 37 citations

STUDIES ON HUMAN ANTIBODIES

1964 • 37 citations

Properties of Structurally Restricted Antibody to Type VIII Pneumococcal Polysaccharide

1970 • 36 citations

Antibodies of limited heterogenety: L chains of a single mobility

1970 • 36 citations

Affinity Labeling of Rabbit Antisaccharide Antibodies^*

1967 • 34 citations

Relationships Between the Heterogeneity of Immunoglobulins and the Differentiation of Plasma Cells

1967 • 34 citations

Properties of Crystallized Rabbit Anti-p-Azobenzoate Antibody

1967 • 33 citations

Isolation of antibodies to the C-terminal heptapeptide of myoglobin with a synthetic peptide

1968 • 33 citations

IV. ANTIGENIC AND BIOCHEMICAL COMPOSITION OF HEMOLYTIC STREPTOCOCCAL CELL WALLS

1963 • 32 citations

Streptococcal group-specific antibodies: occurrence of a restricted population following secondary immunization.

1968 • 31 citations

STUDIES ON THE RELATIONSHIP OF ALLOTYPIC SPECIFICITIES TO ANTIBODY SPECIFICITIES IN THE RABBIT

1963 • 30 citations

Deletions of Allotypic γ-Globulins in Antibodies

1962 • 30 citations

On the associated state of rabbit allotypes, the existence of rabbit antibody molecules against two allotypes, and the dissociation of human γ-globulin antigens into smaller molecules

1961 • 29 citations

Antibodies to Pneumococcal Polysaccharides: Relation between Binding and Electrophoretic Heterogeneity

1968 • 28 citations

Quantitative studies of the specificity of anti-pneumococcal polysaccharide antibodies, types 3 and 8. 3. Binding of a labeled oligosaccharide derived from S8 by anti-S8 antibodies.

1968 • 27 citations

Anti-antibodies

1967 • 27 citations

Studies on Fragments of Light Chains of Human Immunoglobulins: Genetic and Biochemical Implications

1967 • 27 citations

Light Chains of Rabbit Immunoglobulin: Assignment to the Kappa Class

1967 • 25 citations

Affinity and heterogeneity of antibodies induced by iε-2,4-dinitrophenylinsulin

1969 • 25 citations

A resumé of the current status of the development of plasma-cell tumors in mice.

1968 • 25 citations

Specific fractionation of human anti-dextran antibodies—III

1964 • 25 citations

Allotype Suppression with Anti-b5 Antiserum in b5b5 Homozygous Rabbits Fostered in Uteri of b4b4 Homozygous Mothers: Compensation by Allotypes at Other Loci

1969 • 24 citations

Immune Cryoglobulins in Rabbit Streptococcal Antiserum

1968 • 22 citations

AMINO ACID SEQUENCE RESTRICTION IN RABBIT ANTIBODY LIGHT CHAINS

1969 • 21 citations

The proportion of two b locus allotypic determinants in rabbit antisera raised against pneumococcal polysaccharide SSS 3 antigen.

1969 • 21 citations

Studies on human antibodies. VII. Acrylamide gel electrophoresis of purified human antibodies and myeloma proteins, their heavy and light chains.

1969 • 20 citations

Biochemists, Biologists, and William of Occam

1961 • 19 citations

Electrophoretically Homogeneous Anti-DNP Antibodies with Restricted Isoelectric Points Elicited in Mice by Immunization with the Antigen Papain-S-DNPL

1970 • 18 citations

Quantitative Studies of the Specificity of Anti-Pneumococcal Polysaccharide Antibodies, Types III and VIII

1968 • 18 citations

The action of cyanogen bromide on rabbit IgG molecules of allotypes A11 and A12

1970 • 17 citations

Some Contributions of Immunochemistry to Biochemistry and Biology

1967 • 14 citations

Affinity Labeling of Equine Anti-β-lactoside Antibodies^*

1967 • 13 citations

Immunoglobulins

1969 • 12 citations

Electrophoretic Behaviour of Rabbit Gamma-Globulin Fragments and Chains

1964 • 11 citations

Immunochemical Analysis of Streptococcus bovis, Strain s19, Cell Walls

1969 • 11 citations

Heterogeneity of Rabbit Light-Polypeptide Chains

1967 • 10 citations

Studies on Human Antibodies

1969 • 8 citations