Protective immunity elicited by recombinant bacille Calmette-Guerin (BCG) expressing outer surface protein A (OspA) lipoprotein: a candidate Lyme disease vaccine.

Phase separation of integral membrane proteins in Triton X-114 solution.

1981 • 3,366 citations

New use of BCG for recombinant vaccines

1991 • 1,463 citations

In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine

1989 • 632 citations

Lipoproteins in bacteria

1990 • 536 citations

Protection of Mice Against the Lyme Disease Agent by Immunizing with Recombinant OspA

1990 • 480 citations

Genetic control of natural resistance to Mycobacterium bovis (BCG) in mice.

1981 • 343 citations

Lysogeny and transformation in mycobacteria: stable expression of foreign genes.

1988 • 321 citations

Molecular analysis of linear plasmid‐encoded major surface proteins, OspA and OspB, of the Lyme disease spirochaete Borrelia burgdorferi

1989 • 317 citations

Humoral and cell-mediated immune responses to live recombinant BCG–HIV vaccines

1991 • 315 citations

Introduction of foreign DNA into mycobacteria using a shuttle phasmid

1987 • 312 citations

Antigenic Variability of Borrelia burgdorferi

1988 • 298 citations

Immunogenic integral membrane proteins of Borrelia burgdorferi are lipoproteins

1990 • 279 citations

The lipoprotein of the outer membrane of Escherichia coli: a B-lymphocyte mitogen.

1975 • 273 citations

Immune Response to Cholera Toxin Epitope Inserted in Salmonella Flagellin

1989 • 257 citations

Elimination of Borrelia burgdorferi from vector ticks feeding on OspA-immunized mice.

1992 • 243 citations

Probing the topology of a bacterial membrane protein by genetic insertion of a foreign epitope; expression at the cell surface.

1986 • 193 citations

Structure and mapping of antigenic domains of protein antigen b, a 38,000-molecular-weight protein of Mycobacterium tuberculosis

1989 • 187 citations

Recombinant Outer Surface Protein A from Borrelia burgdorferi Induces Antibodies Protective against Spirochetal Infection in Mice

1991 • 185 citations

Identification and localization of integral membrane proteins of virulent Treponema pallidum subsp. pallidum by phase partitioning with the nonionic detergent triton X-114

1988 • 179 citations

Lipoprotein antigens ofMycobacterium tuberculosis

1991 • 174 citations

Roles of OspA, OspB, and flagellin in protective immunity to Lyme borreliosis in laboratory mice

1992 • 173 citations

Cloning and expression of the Mycobacterium bovis BCG gene for extracellular alpha antigen

1988 • 171 citations

The urinary bladder, a consistent source of Borrelia burgdorferi in experimentally infected white-footed mice (Peromyscus leucopus)

1988 • 150 citations

A Single Recombinant Plasmid Expressing Two Major Outer Surface Proteins of the Lyme Disease Spirochete

1985 • 149 citations

Major integral membrane protein immunogens of Treponema pallidum are proteolipids

1989 • 143 citations

In Vitro Inhibition of Borrelia burgdorferi Growth by Antibodies

1993 • 132 citations

Cloning, sequence determination, and expression of a 32-kilodalton-protein gene of Mycobacterium tuberculosis

1989 • 122 citations

Organization of genes encoding two outer membrane proteins of the Lyme disease agent Borrelia burgdorferi within a single transcriptional unit

1986 • 116 citations

Outer surface protein a (OspA) from the lyme disease spirochete, borrelia burgdorferi: High level expression and purification of a soluble recombinant form of OspA

1990 • 103 citations

Human T cell clones recognize two abundant Mycobacterium tuberculosis protein antigens expressed in Escherichia coli.

1987 • 101 citations

Clinical value of the measurement of Mycobacterium tuberculosis specific antibody in pulmonary tuberculosis.

1992 • 100 citations

Establishment of a foreign antigen secretion system in mycobacteria

1990 • 91 citations

Humoral and cell-mediated immunity in mice to a 17-kilodalton lipoprotein of Francisella tularensis expressed by Salmonella typhimurium

1992 • 87 citations

Biologic activities of antibody to a peptidoglycan-associated lipoprotein of Haemophilus influenzae against multiple clinical isolates of H. influenzae type b

1987 • 84 citations

Lipopeptide Derivatives of Bacterial Lipoprotein Constitute Potent Immune Adjuvants Combined with or Covalently Coupled to Antigen or Hapten

1989 • 82 citations

Nucleotide sequence of the 19 kDa antigen gene fromMycobacterium tuberculosis

1989 • 73 citations

Cloning and expression of the gene for the cross-reactive alpha antigen of Mycobacterium kansasii

1990 • 71 citations

Surface expression of malarial antigens in Salmonella typhimurium: induction of serum antibody response upon oral vaccination of mice

1991 • 70 citations

Evidence for three separate genes encoding the proteins of the mycobacterial antigen 85 complex

1990 • 69 citations

Protection against experimental Pseudomonas aeruginosa infection by recombinant P. aeruginosa lipoprotein I expressed in Escherichia coli

1990 • 57 citations

Development of BCG As a Recombinant Vaccine Vehicle

1990 • 45 citations

Molecular cloning, expression, and DNA sequence analysis of the gene that encodes the 16-kilodalton outer membrane lipoprotein of Serpulina hyodysenteriae

1993 • 38 citations

The major anaerobically induced outer membrane protein of Neisseria gonorrhoeae, Pan 1, is a lipoprotein

1992 • 37 citations

Antibodies to a Common Outer Envelope Antigen of Treponema hyodysenteriae with Antibacterial Activity

1989 • 32 citations

K88 fimbriae as carriers of heterologous antigenic determinants

1990 • 27 citations

Expression of viral hemagglutinin on the surface ofE. coli

1988 • 18 citations

Deleted Work

1955 • 0 citations