Intratumoral T cells, tumor-associated macrophages, and regulatory T cells: Association with p53 mutations, circulating tumor DNA and survival in women with ovarian cancer

Cancer Statistics, 2006

2006 • 5,351 citations

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

Tumour-educated macrophages promote tumour progression and metastasis

2004 • 3,259 citations

Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer

2003 • 3,194 citations

Intraepithelial CD8⁺tumor-infiltrating lymphocytes and a high CD8⁺/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

2005 • 2,226 citations

The role of tumour‐associated macrophages in tumour progression: implications for new anticancer therapies

2002 • 1,941 citations

Free DNA in the serum of cancer patients and the effect of therapy.

1977 • 1,708 citations

Colony-Stimulating Factor 1 Promotes Progression of Mammary Tumors to Malignancy

2001 • 1,556 citations

Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse

2006 • 1,118 citations

MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis

2002 • 879 citations

Increased Populations of Regulatory T Cells in Peripheral Blood of Patients with Hepatocellular Carcinoma

2005 • 618 citations

Quantification of Free Circulating DNA As a Diagnostic Marker in Lung Cancer

2003 • 554 citations

The Expression of the Regulatory T Cell–Specific Forkhead Box Transcription Factor FoxP3 Is Associated with Poor Prognosis in Ovarian Cancer

2005 • 494 citations

Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers.

2003 • 487 citations

Analysis of circulating tumor DNA in plasma at diagnosis and during follow-up of lung cancer patients.

2001 • 384 citations

p53 and breast cancer, an update

2006 • 372 citations

Tumor-Associated Macrophages: The Double-Edged Sword in Cancer Progression

2004 • 363 citations

Frequent allelic losses and mutations of the p53 gene in human ovarian cancer.

1991 • 194 citations

Prognostic significance of CD3+ tumor-infiltrating lymphocytes in ovarian carcinoma

2007 • 183 citations

Mutation and overexpression of p53 in early-stage epithelial ovarian cancer.

1993 • 168 citations

A mouse mutant p53 product recognized by CD4+ and CD8+ T cells.

1994 • 168 citations

Immunization With Mutantp53- andK-ras–Derived Peptides in Cancer Patients: Immune Response and Clinical Outcome

2005 • 164 citations

Tumor-specific p53 sequences in blood and peritoneal fluid of women with epithelial ovarian cancer

2005 • 123 citations

Increased Prevalence of Regulatory T Cells (Treg) is Induced by Pancreas Adenocarcinoma

2006 • 113 citations

p53 Biological Network: At the Crossroads of the Cellular-Stress Response Pathway and Molecular Carcinogenesis

2006 • 108 citations

Prognostic relevance of tumour-associated macrophages and von Willebrand factor-positive microvessels in colorectal cancer

2004 • 72 citations

Factors associated with cytoreducibility among women with ovarian carcinoma

2004 • 55 citations

P53‐specific T cell responses in patients with malignant and benign ovarian tumors: Implications for p53 based immunotherapy

2007 • 34 citations

Upregulation of bikunin in tumor-infiltrating macrophages as a factor of favorable prognosis in ovarian cancer

2004 • 29 citations

Increased frequencies of CD8+ T lymphocytes recognizing wild‐type p53‐derived epitopes in peripheral blood correlate with presence of epitope loss tumor variants in patients with hepatocellular carcinoma

2006 • 27 citations

Human Monocyte-Derived Dendritic Cells Pulsed with Wild-Type p53 Protein Efficiently Induce CTLs against p53 Overexpressing Human Cancer Cells

2005 • 17 citations