Arterial endothelin-1 level in pulmonary emphysema and interstitial lung disease. Relation with pulmonary hypertension during exercise

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Standards for the Diagnosis and Care of Patients with Chronic Obstructive Pulmonary Disease

1995 • 3,549 citations

Principles of Exercise Testing and Interpretation.

1987 • 2,278 citations

Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension

1993 • 1,829 citations

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

1988 • 1,417 citations

Principles of Exercise Testing and Interpretation

1987 • 1,112 citations

Increased Plasma Endothelin-1 in Pulmonary Hypertension: Marker or Mediator of Disease?

1991 • 983 citations

Endothelin stimulates c‐fos and c‐myc expression and proliferation of vascular smooth muscle cells

1988 • 737 citations

Hypoxia induces endothelin gene expression and secretion in cultured human endothelium.

1991 • 691 citations

Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part One.

1994 • 476 citations

Hypoxia on the pulmonary circulation. How and where it acts.

1976 • 465 citations

Plasma endothelin concentrations in patients with pulmonary hypertension associated with congenital heart defects. Evidence for increased production of endothelin in pulmonary circulation.

1991 • 340 citations

Contribution of endogenous endothelin-1 to the progression of cardiopulmonary alterations in rats with monocrotaline-induced pulmonary hypertension.

1993 • 337 citations

The veterans administration cooperative study of pulmonary function

1966 • 301 citations

Autoradiographic distribution in rat tissues of binding sites for endothelin: a neuropeptide?

1989 • 299 citations

Expression of endothelin-1 in lungs of patients with cryptogenic fibrosing alveolitis

1993 • 284 citations

Endothelin, an endothelial‐dependent vasoconstrictor in scleroderma. Enhanced production and profibrotic action

1991 • 228 citations

Effect of endothelin-1 in man.

1990 • 225 citations

Evidence for endothelin-1 release from resistance vessels of rats in response to hypoxia

1990 • 207 citations

Endothelin-1 in Acute Lung Injury and the Adult Respiratory Distress Syndrome

1993 • 158 citations

Increased lung endothelin-1 production in rats with idiopathic pulmonary hypertension

1992 • 151 citations

Acute pulmonary alveolar hypoxia increases lung and plasma endothelin-1 levels in conscious rats

1991 • 132 citations

Endothelin produces pulmonary vasoconstriction and systemic vasodilation

1989 • 124 citations

Increased endothelin receptor gene expression in hypoxic rat lung

1994 • 122 citations

Elimination of Intravenously Injected Endothelin-1 from the Circulation of the Rat

1989 • 112 citations

The normal lung

1987 • 112 citations

Endothelin in bronchoalveolar lavage fluid and its relation to airflow obstruction in asthma.

1995 • 107 citations

Endothelin and the respiratory system

1993 • 90 citations

The Normal Lung: The Basis for Diagnosis and Treatment of Pulmonary Disease

1985 • 84 citations

Bicycle endurance performance of patients with interstitial lung disease breathing air and oxygen.

1982 • 76 citations

Endothelin-1 synthesis, receptors, and signal transduction in alveolar epithelium: evidence for an autocrine role

1995 • 55 citations

Endothelin in Bronchoalveolar Lavage Fluid and its Relation to Airflow Obstruction in Asthma

1995 • 50 citations

Contribution of endothelin-1 to warm ischemia/reperfusion injury of the rat lung.

1995 • 45 citations

The Normal Lung: The Basis for Diagnosis and Treatment of Pulmonary Disease

1986 • 42 citations

Metabolic and vascular effects of circulating endothelin-1 during moderately heavy prolonged exercise

1995 • 40 citations

Factors associated with vasopressin release in exercising swine

1994 • 25 citations

Effects of exercise‐training on hypoxia and angiotensin II‐induced pulmonary vasoconstrictions

1995 • 22 citations

The Veterans Administration Cooperative Study of Pulmonary Function. III. Mortality in Relation to Respiratory Function in Chronic Obstructive Pulmonary Disease

1967 • 15 citations

The Role of Exercise Testing in Pulmonary Diagnosis

1987 • 12 citations

Endothelin and atrial natriuretic peptide after exercise performed until exhaustion in the rat

1991 • 9 citations

Endothelin Receptors and Receptor Subtypes

1992 • 7 citations