Endothelin Receptors and Receptor Subtypes

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Cloning and expression of a cDNA encoding an endothelin receptor

1990 • 2,590 citations

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

1989 • 2,551 citations

Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

1990 • 2,432 citations

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

1988 • 1,417 citations

Endothelin stimulates phospholipase C, Na+/H+ exchange, c-fos expression, and mitogenesis in rat mesangial cells.

1989 • 561 citations

Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide.

1988 • 551 citations

A novel vasoactive peptide endothelin stimulates mitogenesis through inositol lipid turnover in Swiss 3T3 fibroblasts

1989 • 485 citations

Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney. Elucidation of signal transduction pathways.

1989 • 413 citations

Sarafotoxin, a Novel Vasoconstrictor Peptide: Phosphoinositide Hydrolysis in Rat Heart and Brain

1988 • 362 citations

Endothelin: A Novel Peptide in the Posterior Pituitary System

1990 • 313 citations

Endothelin is a potent secretagogue for atrial natriuretic peptide in cultured rat atrial myocytes

1988 • 299 citations

Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat

1989 • 260 citations

Endothelin receptor is coupled to phospholipase C via a pertussis toxin-insensitive guanine nucleotide-binding regulatory protein in vascular smooth muscle cells.

1990 • 187 citations

Two distinct types of endothelin receptors are present on chick cardiac membranes

1989 • 176 citations

Endothelin inhibits renin release from isolated rat glomeruli

1988 • 165 citations

Two different forms of endothelin receptors in rat lung

1989 • 117 citations

Elimination of Intravenously Injected Endothelin-1 from the Circulation of the Rat

1989 • 112 citations

Identification of two types of specific endothelin receptors in rat mesangial cell

1989 • 82 citations

Identification and characterization of endothelin binding sites in rat renal papillary and glomerular membranes

1989 • 78 citations

Purification of an endothelin receptor from human placenta

1990 • 67 citations

Solubilization and identification of human placental endothelin receptor

1989 • 47 citations

Effects of vasoactive intestinal contractor (VIC) and endothelin on intracellular calcium level in neuroblastoma NG108‐15 cells

1989 • 45 citations

Identification of the Endothelin-1 Receptor in the Chick Heart

1989 • 25 citations

Affinity labelling of endothelin receptor and characterization of solubilized endothelin–endothelin‐receptor complex

1990 • 16 citations