Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble

The leucine-rich repeat as a protein recognition motif

2001 • 1,584 citations

Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ

1996 • 1,127 citations

Cooperative Regulation of Cell Polarity and Growth by Drosophila Tumor Suppressors

2000 • 908 citations

The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions

1991 • 902 citations

Localization of apical epithelial determinants by the basolateral PDZ protein Scribble

2000 • 678 citations

scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila

2003 • 587 citations

The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44

2001 • 546 citations

Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors

2004 • 528 citations

Epithelial Cell Polarity and Cell Junctions inDrosophila

2001 • 516 citations

A Genetic Screen in Drosophila for Metastatic Behavior

2003 • 498 citations

Complete Polarization of Single Intestinal Epithelial Cells upon Activation of LKB1 by STRAD

2004 • 492 citations

Malignant Neoplasms of Genetic Origin in Drosophila melanogaster

1978 • 441 citations

Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia.

1996 • 422 citations

A Drosophila Neurexin Is Required for Septate Junction and Blood-Nerve Barrier Formation and Function

1996 • 419 citations

Parameters of the wing imaginal disc development ofDrosophila melanogaster

1971 • 364 citations

A Genetic Method for Generating Drosophila Eyes Composed Exclusively of Mitotic Clones of a Single Genotype

1999 • 336 citations

Molecular organization of the postsynaptic specialization

2001 • 330 citations

A Drosophila homologue of membrane-skeleton protein 4.1 is associated with septate junctions and is encoded by the coracle gene

1994 • 304 citations

ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor

2000 • 289 citations

NF2deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions

2003 • 285 citations

LET-23 Receptor Localization by the Cell Junction Protein LIN-7 during C. elegans Vulval Induction

1996 • 268 citations

Intrinsic and Extrinsic Control of Growth in Developing Organs

1984 • 250 citations

Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells

2004 • 220 citations

Mammalian Scribble Forms a Tight Complex with the βPIX Exchange Factor

2004 • 212 citations

LET-413 is a basolateral protein required for the assembly of adherens junctions in Caenorhabditis elegans

2000 • 186 citations

Control of growth and organ size in Drosophila

2002 • 178 citations

Molecular cloning of the lethal(1)discs large-1 oncogene of Drosophila

1989 • 176 citations

Basolateral targeting by leucine‐rich repeat domains in epithelial cells

2003 • 150 citations

Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large

1997 • 136 citations

The Drosophila lethal(2)giant larvae tumor suppressor protein is a component of the cytoskeleton.

1994 • 134 citations

Erbin Suppresses the MAP Kinase Pathway

2003 • 113 citations

Drosophila in cancer research: the first fifty tumor suppressor genes

1994 • 109 citations

The LAP family: a phylogenetic point of view

2002 • 81 citations

PDZ proteins and polarity: functions from the fly

2001 • 73 citations

Drosophila Immunity: Genes on the Third Chromosome Required for the Response to Bacterial Infection

2001 • 49 citations

Direct determination of the growth rate of Drosophila imaginal discs

1982 • 46 citations

Basolateral targeting by leucine-rich repeat domains in epithelial cells

2003 • 36 citations