Inhibition of growth and induction of TGF-β1 in human hepatocellular carcinoma with androgen receptor by cyproterone acetate in male nude mice

Nonparametric Statistical Methods

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pl5INK4B is a potentia| effector of TGF-β-induced cell cycle arrest

1994 • 1,932 citations

Cyclin/PCNA is the auxiliary protein of DNA polymerase-δ

1987 • 1,766 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells

1987 • 998 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors.

1987 • 895 citations

A new method to detect apoptosis in paraffin sections: in situ end-labeling of fragmented DNA.

1993 • 823 citations

Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation

1990 • 812 citations

POSSIBLE ASSOCIATION BETWEEN BENIGN HEPATOMAS AND ORAL CONTRACEPTIVES

1973 • 623 citations

TGFβ inhibition of Cdk4 synthesis is linked to cell cycle arrest

1993 • 544 citations

Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation.

1990 • 485 citations

Programmed cell death during regression of the MCF-7 human breast cancer following estrogen ablation.

1991 • 429 citations

Expression of Transforming Growth Factor-β in the Rat Ventral Prostate during Castration-Induced Programmed Cell Death

1989 • 417 citations

Anti-oestrogens induce the secretion of active transforming growth factor beta from human fetal fibroblasts

1990 • 324 citations

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1983 • 319 citations

Differential effects of transforming growth factor-beta on proliferation of normal and malignant rat liver epithelial cells in culture.

1986 • 224 citations

Transforming growth factor—beta 1 (TGF-β1) and TGF-β1 receptors in normal, cirrhotic, and neoplastic human livers

1995 • 219 citations

The natural history of hepatocellular carcinoma. A study of 100 untreated cases

1984 • 215 citations

Apoptosis in Toremifene-Induced Growth Inhibition of Human Breast Cancer Cells In Vivo and In Vitro

1993 • 192 citations

In vitro apoptosis in the human hepatoma cell line induced by transforming growth factor beta 1.

1992 • 190 citations

Differential regulation of expression of three transforming growth factor beta species in human breast cancer cell lines by estradiol.

1990 • 160 citations

Programmed death of nonproliferating androgen-independent prostatic cancer cells.

1991 • 159 citations

Elevated levels of transforming growth factor beta messenger RNA and its polypeptide in human hepatocellular carcinoma.

1991 • 150 citations

Androgen receptors in hepatocellular carcinoma and surrounding parenchyma

1985 • 134 citations

The growth inhibition of human breast cancer cells by a novel synthetic progestin involves the induction of transforming growth factor beta.

1991 • 122 citations

Estrogen receptors in hepatocellular carcinoma

1986 • 118 citations

Induction of apoptosis by transforming growth factor-β1 in the rat hepatoma cell line MCA-RH7777: A possible association with tissue transglutaminase expression

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ORAL-CONTRACEPTIVE-ASSOCIATED LIVER TUMOURS: OCCURRENCE OF MALIGNANCY AND DIFFICULTIES IN DIAGNOSIS

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Mechanistic interrelationships between two superfamilies: the steroid/retinoid receptors and transforming growth factor-beta.

1992 • 90 citations

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1988 • 88 citations

Androgen and oestrogen receptors in hepatocellular carcinoma and surrounding liver parenchyma: Impact on intrahepatic recurrence after hepatic resection

1995 • 78 citations

Differential gene regulation during programmed death (apoptosis) versus proliferation of prostatic glandular cells induced by androgen manipulation.

1993 • 74 citations

Inhibition of proliferation of normal, preneoplastic, and neoplastic rat hepatocytes by transforming growth factor-beta.

1987 • 71 citations

Androgen and estrogen receptors in hepatocellular carcinoma and the surrounding liver in women

1989 • 69 citations

Androgen repression of the production of a 29-kilodalton protein and its mRNA in the rat ventral prostate.

1987 • 61 citations

Development of resistance to the growth inhibitory effects of transforming growth factor beta 1 during the spontaneous transformation of rat liver epithelial cells.

1991 • 58 citations

Response to cyproterone acetate treatment in primary hepatocellular carcinoma is related to fall in free 5α-dihydrotestosterone

1987 • 58 citations

Androgen Receptor in Hepatocellular Carcinoma as a Prognostic Factor After Hepatic Resection

1989 • 53 citations

Quantitation of estrogen and androgen receptors in hepatocellular carcinoma and adjacent normal human liver

1991 • 52 citations

Transforming growth factor beta 1 in liver carcinogenesis: messenger RNA expression and growth effects.

1990 • 50 citations

Progesterone receptor in hepatocellular carcinoma. Correlation with androgen and estrogen receptors

1991 • 37 citations

Primary hepatocellular carcinoma in women of mainland china a clinicopathologic analysis of 104 patients

1993 • 26 citations

Effect of androgens and their manipulation on cell growth and androgen receptor (AR) levels in AR-positive and -negative human hepatocellular carcinomas

1995 • 26 citations

Differential gene regulation during programmed death (apoptosis) versus proliferation of prostatic glandular cells induced by androgen manipulation

1993 • 24 citations

Pathology of Hepatocellular Carcinoma

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Interaction of cyproterone acetate with rat prostatic androgen receptors

1985 • 9 citations