Elevated preoperative serum levels of angiogenic cytokines correlate to larger primary tumours and poorer survival in non-small cell lung cancer patients
Data up to Jan 2025
Total Citations Per Year
Abstract
References (37)
TNM Classification of Malignant Tumours
1987 • 16,209 citations
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
1996 • 6,878 citations
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
1992 • 4,631 citations
The Biology of Vascular Endothelial Growth Factor
1997 • 4,359 citations
Vascular-specific growth factors and blood vessel formation
2000 • 3,667 citations
The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor
1992 • 2,042 citations
High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
1993 • 1,961 citations
The Biology of Vascular Endothelial Growth Factor
1997 • 1,203 citations
Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
1992 • 865 citations
Relation of neovascularisation to metastasis of non-small-cell lung cancer
1992 • 780 citations
Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets: significance for VEGF measurements and cancer biology
1998 • 608 citations
Synergistic Effect of Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor on Angiogenesis In Vivo
1995 • 605 citations
Fibroblast growth factor: Structural and biological properties
1987 • 334 citations
Alternative Translation of Human Fibroblast Growth Factor 2 mRNA Occurs by Internal Entry of Ribosomes
1995 • 332 citations
Pitfalls in the Measurement of Circulating Vascular Endothelial Growth Factor
2001 • 325 citations
Angiogenesis as a Prognostic Indicator of Survival in Non-Small-Cell Lung Carcinoma: a Prospective Study
1997 • 309 citations
Elevated levels of the angiogenic cytokines basic fibroblast growth factor and vascular endothelial growth factor in sera of cancer patients
1997 • 288 citations
High pre-treatment serum level of vascular endothelial growth factor (VEGF) is associated with poor outcome in small-cell lung cancer
1998 • 275 citations
Functional Upregulation of the Vascular Endothelial Growth Factor Receptor KDR by Hypoxia
1996 • 261 citations
Vascular Endothelial Growth Factor Expression in Stage I Non-Small Cell Lung Cancer Correlates With Neoangiogenesis and a Poor Prognosis
2001 • 208 citations
Vascular endothelial growth factor is essential for initial but not continued in vivo growth of human breast carcinoma cells.
1997 • 203 citations
Serum vascular endothelial growth factor is often elevated in disseminated cancer.
1997 • 181 citations
Expression of vascular endothelial growth factor (VEGF) and its two receptors (VEGF‐R1‐Flt1 and VEGF‐R2‐Flk1/KDR) in non‐small cell lung carcinomas (NSCLCs): correlation with angiogenesis and survival
1999 • 177 citations
Vascular endothelial growth factor expression in non-small-cell lung cancer: Prognostic significance in squamous cell carcinoma
1998 • 175 citations
The high molecular weight isoforms of basic fibroblast growth factor (FGF‐2): an insight into an intracrine mechanism
2000 • 150 citations
HIF-1alpha-mediated up-regulation of vascular endothelial growth factor, independent of basic fibroblast growth factor, is important in the switch to the angiogenic phenotype during early tumorigenesis.
2001 • 125 citations
Fibroblast growth factor 2: its structure and property, paracrine function, tumor angiogenesis, and prostate-related mitogenic and oncogenic functions
2000 • 123 citations
Clinical usefulness of serum and plasma vascular endothelial growth factor in cancer patients: which is the optimal specimen?
2000 • 97 citations
Vascular endothelial growth factor expression and neovascularisation in non-small cell lung cancer
2000 • 95 citations
Identification and characterization of a new splicing variant of vascular endothelial growth factor: VEGF183
1998 • 89 citations
Basic fibroblast growth factor and vascular endothelial growth factor in sera from non-small cell lung cancer patients.
1998 • 81 citations
Prognostic value of basic fibroblast growth factor and its receptor (FGFR-1) in patients with non-small cell lung carcinomas
1997 • 79 citations
Elevated vascular endothelial growth factor levels in sera of patients with lung cancer.
1998 • 77 citations
Relationship between vascularity, age and survival in non-small-cell lung cancer
1997 • 73 citations
The basic fibroblast growth factor and its receptor in pulmonary adenocarcinomas: an investigation of their expression as prognostic markers
1996 • 55 citations
Prognostic value of vascularity and vascular endothelial growth factor expression in non-small cell lung cancer
2001 • 46 citations
'Tumour volume' as a predictor of survival after resection of non-small-cell lung cancer (NSCLC)
1996 • 24 citations