Glycan-dependent leukocyte adhesion and recruitment in inflammation

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

The Biology of Chemokines and their Receptors

2000 • 2,416 citations

The Role of Chemokine Receptors in Primary, Effector, and Memory Immune Responses

2000 • 1,077 citations

Mechanisms That Regulate the Function of the Selectins and Their Ligands

1999 • 931 citations

Fucose: biosynthesis and biological function in mammals

2003 • 870 citations

Expression cloning of a functional glycoprotein ligand for P-selectin

1993 • 734 citations

The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis

1996 • 723 citations

Chemokines and the Tissue-Specific Migration of Lymphocytes

2002 • 692 citations

A Genetic Approach to Mammalian Glycan Function

2003 • 582 citations

A carbohydrate domain common to both sialyl Le(a) and sialyl Le(X) is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1

1991 • 480 citations

PSGL-1 recognition of P-selectin is controlled by a tyrosine sulfation consensus at the PSGL-1 amino terminus

1995 • 383 citations

The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor

1995 • 358 citations

Neutrophil-neutrophil interactions under hydrodynamic shear stress involve L-selectin and PSGL-1. A mechanism that amplifies initial leukocyte accumulation of P-selectin in vitro.

1996 • 353 citations

Avidity regulation of integrins: the driving force in leukocyte adhesion

2000 • 342 citations

Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency

2001 • 340 citations

Post-translational Modifications of Recombinant P-selectin Glycoprotein Ligand-1 Required for Binding to P- and E-selectin

1996 • 340 citations

The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter

2001 • 329 citations

Novel Sulfated Lymphocyte Homing Receptors and Their Control by a Core1 Extension β1,3-N-Acetylglucosaminyltransferase

2001 • 327 citations

Targeted Gene Disruption Demonstrates That P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is Required for P-Selectin–Mediated but Not E-Selectin–Mediated Neutrophil Rolling and Migration

1999 • 327 citations

The α(1,3)fucosyltransferases FucT-IV and FucT-VII Exert Collaborative Control over Selectin-Dependent Leukocyte Recruitment and Lymphocyte Homing

2001 • 315 citations

The Leukocyte Integrins

2000 • 309 citations

Core 2 Oligosaccharide Biosynthesis Distinguishes between Selectin Ligands Essential for Leukocyte Homing and Inflammation

1998 • 308 citations

Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions

1999 • 291 citations

Tyrosine Sulfation of P-selectin Glycoprotein Ligand-1 Is Required for High Affinity Binding to P-selectin

1995 • 290 citations

Correction of Leukocyte Adhesion Deficiency Type II With Oral Fucose

1999 • 274 citations

Growth retardation and early death of beta -1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cells

1997 • 270 citations

T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination.

1995 • 266 citations

Specialized Contributions by α(1,3)-Fucosyltransferase-IV and FucT-VII during Leukocyte Rolling in Dermal Microvessels

2000 • 261 citations

Structures of the O-Glycans on P-selectin Glycoprotein Ligand-1 from HL-60 Cells

1996 • 260 citations

Glycosylation in the control of selectin counter‐receptor structure and function

2002 • 242 citations

P-selectin glycoprotein ligand-1–deficient mice have impaired leukocyte tethering to E-selectin under flow

2002 • 241 citations

Sperm from β1,4-galactosyltransferase-null mice are refractory to ZP3-induced acrosome reactions and penetrate the zona pellucida poorly

1997 • 220 citations

Characterization of the full length cDNA for murine beta-1,4-galactosyltransferase. Novel features at the 5′-end predict two translational start sites at two in-frame AUGs.

1988 • 217 citations

Molecular Cloning and Expression of a Novel β-1,6-N-Acetylglucosaminyltransferase That Forms Core 2, Core 4, and I Branches

1999 • 216 citations

A Novel Glycosulfopeptide Binds to P-selectin and Inhibits Leukocyte Adhesion to P-selectin

1999 • 215 citations

P-selectin glycoprotein ligand-1–deficient mice have impaired leukocyte tethering to E-selectin under flow

2002 • 196 citations

Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection.

1993 • 187 citations

Tyrosylprotein sulfotransferase: Purification and molecular cloning of an enzyme that catalyzes tyrosine O -sulfation, a common posttranslational modification of eukaryotic proteins

1998 • 166 citations

Molecular Cloning of a Novel α2,3-Sialyltransferase (ST3Gal VI) That Sialylates Type II Lactosamine Structures on Glycoproteins and Glycolipids

1999 • 160 citations

Conditional control of selectin ligand expression and global fucosylation events in mice with a targeted mutation at the FX locus

2002 • 154 citations

L-Selectin from Human, but Not from Mouse Neutrophils Binds Directly to E-Selectin

1997 • 151 citations

Targeted Mutation in β1,4-Galactosyltransferase Leads to Pituitary Insufficiency and Neonatal Lethality

1997 • 148 citations

Sialyltransferase specificity in selectin ligand formation

2002 • 133 citations

Control of O-Glycan Branch Formation

2000 • 130 citations

Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase–deficient mice

2001 • 119 citations

Monosialogangliosides of Human Myelogenous Leukemia HL60 Cells and Normal Human Leukocytes. 2. Characterization of E-Selectin Binding Fractions, and Structural Requirements for Physiological Binding to E-Selectin

1996 • 112 citations

Cloning and Characterization of a Ninth Member of the UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase Family, ppGaNTase-T9

2001 • 105 citations

Novel chemokine functions in lymphocyte migration through vascular endothelium under shear flow

2001 • 100 citations

Differential requirements for the O-linked branching enzyme core 2 β1-6-N-glucosaminyltransferase in biosynthesis of ligands for E-selectin and P-selectin

2001 • 93 citations

Impaired selectin-ligand biosynthesis and reduced inflammatory responses in β-1,4-galactosyltransferase-I–deficient mice

2003 • 89 citations

The Cutaneous Lymphocyte Antigen Is an Essential Component of the L-selectin Ligand Induced on Human Vascular Endothelial Cells

1999 • 83 citations

Reduced Body Weight and Increased Postimplantation Fetal Death in Tyrosylprotein Sulfotransferase-1-deficient Mice

2002 • 80 citations

Composition of Drosophila melanogaster Proteome Involved in Fucosylated Glycan Metabolism

2002 • 78 citations

Glycosulfopeptides with O-Glycans Containing Sialylated and Polyfucosylated Polylactosamine Bind with Low Affinity to P-selectin

2002 • 60 citations

Knockout of mouse β1,4-galactosyltransferase-1 gene results in a dramatic shift of outer chain moieties of N-glycans from type 2 to type 1 chains in hepatic membrane and plasma glycoproteins

2001 • 57 citations

Integrin Activation

2001 • 52 citations

Polymorphonuclear Leukocytes from Individuals Carrying the G329A Mutation in the α1,3-Fucosyltransferase VII Gene (FUT7) Roll on E- and P-Selectins

2002 • 35 citations

Knockout of mouse β1,4-galactosyltransferase-1 gene results in a dramatic shift of outer chain moieties of N-glycans from type 2 to type 1 chains in hepatic membrane and plasma glycoproteins

2001 • 19 citations