T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

Viral dynamics in human immunodeficiency virus type 1 infection

1995 • 3,277 citations

Selection of single-stranded DNA molecules that bind and inhibit human thrombin

1992 • 2,361 citations

HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure

1990 • 1,560 citations

Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene

1992 • 917 citations

Current concepts in antisense drug design

1993 • 566 citations

Animal cell culture; a practical approach

1993 • 432 citations

Three-dimensional Solution Structure of the Thrombin-binding DNA Aptamer d(GGTTGGTGTGGTTGG)

1994 • 379 citations

A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA

1993 • 330 citations

GLQ223: an inhibitor of human immunodeficiency virus replication in acutely and chronically infected cells of lymphocyte and mononuclear phagocyte lineage.

1989 • 307 citations

Combinatorially selected guanosine-quartet structureis a potent inhibitor of human immunodeficiency virus envelope-mediated cellfusion.

1994 • 297 citations

Cholesteryl-conjugated oligonucleotides: synthesis, properties, and activity as inhibitors of replication of human immunodeficiency virus in cell culture.

1989 • 296 citations

Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100

1994 • 295 citations

Inhibitors of human immunodeficiency virus integrase.

1993 • 275 citations

Antiviral and antimetabolic activities of neplanocins

1985 • 212 citations

Evidence that T cell activation is required for HIV-1 entry in CD4+ lymphocytes.

1989 • 177 citations

Quantitative infectivity assay for HIV-1 and -2

1988 • 163 citations

Quantitative Immunocytofluorographic Analysis of CD4 Surface Antigen Expression and HIV Infection of Human Peripheral Blood Monocyte/Macrophages

1987 • 153 citations

Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs

1991 • 130 citations

Suppression of Human Immunodeficiency Virus Type 1 Activity in Vitro by Oligonucleotides Which Form Intramolecular Tetrads

1995 • 118 citations

Intramolecular G-quartet Motifs Confer Nuclease Resistance to a Potent Anti-HIV Oligonucleotide

1996 • 113 citations

Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus type 1 (HIV-1): interference with early and late events in HIV-1 replication

1995 • 104 citations

Long-term treatment of human immunodeficiency virus-infected cells with antisense oligonucleotide phosphorothioates.

1993 • 104 citations

Inhibitory effect of selected antiviral compounds on arenavirus replication in vitro

1990 • 93 citations

Effect of Phosphorothioate Homo-oligodeoxy nucleotides on Herpes Simplex Virus Type 2-induced DNA Polymerase

1989 • 85 citations

A Bioassay for HIV-1 Based on Env-CD4 Interaction

1990 • 83 citations

Phosphorothioate Oligodeoxynucleotides Bind to the Third Variable Loop Domain (v3) of Human Immunodeficiency Virus Type 1 gp120

1993 • 82 citations

Potent and Specific Inhibition of HIV Envelope-Mediated Cell Fusion and Virus Binding by G Quartet-Forming Oligonucleotide (ISIS 5320)

1994 • 78 citations

Characterization of an HIV-1 Isolate Displaying an Apparent Absence of Virion-Associated Reverse Transcriptase Activity

1991 • 74 citations

Potential mechanisms for the cytopathic properties of HIV

1989 • 69 citations

Inhibition of human immunodeficiency virus type 1 integrase by 3'-azido-3'-deoxythymidylate.

1994 • 66 citations

A TIBO derivative, R82913, is a potent inhibitor of HIV-1 reverse transcriptase with heteropolymer templates

1991 • 66 citations

Inhibition of human immunodeficiency virus activity by phosphorodithioate oligodeoxycytidine.

1992 • 62 citations

Oxathiin carboxanilide, a potent inhibitor of human immunodeficiency virus reproduction.

1991 • 61 citations

Inhibitory Effect of the Polyanionic Drug Suramin on the in Vitro HIV DNA Integration Reaction

1993 • 48 citations

Virus Isolation and Production

1990 • 42 citations

Inhibition of human immunodeficiency virus type 1 activity in vitro by oligonucleotides composed entirely of guanosine and thymidine.

1994 • 35 citations

Inhibition of human cytomegalovirus in culture by alkenyl guanine analogs of the thiazolo[4,5-d]pyrimidine ring system

1994 • 33 citations

In vitro evaluation of the antiviral activity of SP‐303, an euphorbiaceae shrub extract, against a panel of respiratory viruses

1993 • 26 citations

Sulfonic acid dyes: inhibition of the human immunodeficiency virus and mechanism of action.

1992 • 25 citations