Adenovirus-Mediated p21 ^{(WAF1/SDII/CIP1)} Gene Transfer Induces Apoptosis of Human Cervical Cancer Cell Lines

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

p21 is a universal inhibitor of cyclin kinases

1993 • 3,408 citations

G1 phase progression: Cycling on cue

1994 • 2,706 citations

Bcl-2 and the regulation of programmed cell death

1994 • 2,346 citations

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1994 • 1,669 citations

Cloning of Senescent Cell-Derived Inhibitors of DNA Synthesis Using an Expression Screen

1994 • 1,368 citations

Apoptosis in cancer therapy: Crossing the threshold

1994 • 1,351 citations

Conversion of Bcl-2 to a Bax-like Death Effector by Caspases

1997 • 1,116 citations

The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines.

1991 • 857 citations

Molecular Ordering of the Cell Death Pathway

1996 • 589 citations

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation.

1993 • 514 citations

Detection of cancer micrometastases in lymph nodes by reverse transcriptase-polymerase chain reaction.

1995 • 366 citations

In vivo gene therapy with p53 or p21 adenovirus for prostate cancer.

1995 • 227 citations

The E3-11.6-kDa Adenovirus Death Protein (ADP) Is Required for Efficient Cell Death: Characterization of Cells Infected withadpMutants

1996 • 223 citations

Suppression of cellular proliferation by the papillomavirus E2 protein

1995 • 220 citations

Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis

1997 • 219 citations

E4orf4, a Novel Adenovirus Death Factor That Induces p53-independent Apoptosis by a Pathway That Is Not Inhibited by zVAD-fmk

1998 • 214 citations

Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck.

1995 • 180 citations

Inhibition of cervical carcinoma cell line proliferation by the introduction of a bovine papillomavirus regulatory gene

1993 • 159 citations

Tumor suppression by p21WAF1.

1995 • 107 citations

Suppression of human bladder cancer growth by increased expression of C-CAM1 gene in an orthotopic model.

1996 • 87 citations

Tumour suppressive properties of the adenovirus 5 E1A oncogene.

1996 • 84 citations

Application of a tumor suppressor (C-CAM1)-expressing recombinant adenovirus in androgen-independent human prostate cancer therapy: a preclinical study.

1995 • 69 citations

Effects of ectopic overexpression of p21(WAF1/CIP1) on aneuploidy and the malignant phenotype of human brain tumor cells.

1996 • 68 citations

Up-regulated P21CIP1 expression is part of the regulation quantitatively controlling serum deprivation-induced apoptosis

1997 • 51 citations

Inhibition of Growth of Human Vascular Smooth Muscle Cells by Overexpression of p21 Gene Through Induction of Apoptosis

1998 • 43 citations

Involvement of p53 and WAF1/CIP1 in γ-Irradiation-Induced Apoptosis of Retinoblastoma Cells

1997 • 31 citations

The Induction of Apoptosis by SV40 T Antigen Correlates with c-junOverexpression

1998 • 24 citations

Bcl-2 Oncogene Protects a Bone Marrow-Derived Pre-B Cell Line from 5′-Fluor,2′-deoxyuridine-Induced Apoptosis

1993 • 22 citations

Overexpression of human p21waf1/cip1 arrests the growth of chicken embryo fibroblasts transformed by individual oncogenes.

1995 • 22 citations

Differential regulation of cyclin A, cyclin B and p21 concentrations in a growth-restricted human fibroblast cell line

1995 • 10 citations