Regulation by interferon alpha of immunoglobulin isotype selection and lymphokine production in mice.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

1989 • 2,771 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

1989 • 1,462 citations

Lymphokine Control of In Vivo Immunoglobulin Isotype Selection

1990 • 1,303 citations

Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors.

1979 • 1,301 citations

IL-4 directs the development of Th2-like helper effectors.

1990 • 1,261 citations

Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores

1989 • 1,199 citations

Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.

1987 • 1,060 citations

Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells.

1990 • 954 citations

IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2.

1988 • 939 citations

Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.

1988 • 845 citations

B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells.

1986 • 797 citations

The Role of Helper T Cell Products in Mouse B Cell Differentiation and Isotype Regulation

1988 • 764 citations

Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1

1985 • 749 citations

IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses.

1988 • 731 citations

A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma.

1986 • 727 citations

Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens.

1988 • 713 citations

Inducers of interferon and host resistance. II. Multistranded synthetic polynucleotide complexes.

1967 • 699 citations

IL-4 is required to generate and sustain in vivo IgE responses.

1988 • 671 citations

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism.

1990 • 629 citations

IgG2a restriction of murine antibodies elicited by viral infections.

1987 • 429 citations

Serological, biochemical, and functional identity of B cell-stimulatory factor 1 and B cell differentiation factor for IgG1.

1985 • 410 citations

A functional dichotomy in CD4+ T lymphocytes

1988 • 369 citations

B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells

1987 • 355 citations

Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10

1990 • 347 citations

Derivation of a T cell line that is highly responsive to IL-4 and IL-2 (CT.4R) and of an IL-2 hyporesponsive mutant of that line (CT.4S).

1989 • 289 citations

Tissue plasminogen activator messenger RNA levels increase in cultured human endothelial cells exposed to laminar shear stress

1990 • 276 citations

Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils.

1991 • 259 citations

Role of interferon in the pathogenesis of virus diseases in mice as demonstrated by the use of anti-interferon serum. I. Rapid evolution of encephalomyocarditis virus infection.

1976 • 254 citations

The Cellular Basis of T-Cell Memory

1989 • 161 citations

RABBIT MACROPHAGE INTERFERONS

1967 • 124 citations

Polyclonal activation of the murine immune system by a goat antibody to mouse IgD. IX. Induction of a polyclonal IgE response.

1987 • 90 citations

IgD-secreting murine plasmacytomas: identification and partial characterization of two IgD myeloma proteins.

1981 • 89 citations

Cellular origin of interferon induced by bacterial lipopolysaccharide

1977 • 87 citations

Interferon Production in Chickens Injected with Brucella abortus

1964 • 80 citations

Regulation of murine in vivo lgG and lgE responses by a monoclonal anti-IL-4 receptor antibody

1991 • 79 citations

Polyclonal activation of the murine immune system by an antibody to IgD. II. Generation of polyclonal antibody production and cells with surface IgG.

1982 • 68 citations

In vitro and in vivo B lymphocyte-activating properties of monoclonal anti-delta antibodies. I. Determinants of B lymphocyte-activating properties.

1986 • 67 citations

T help requirements for the generation of an in vivo IgE response: a late acting form of T cell help other than IL-4 is required for IgE but not for IgG1 production.

1989 • 52 citations

Production of BSF-1 during an in vivo, T-dependent immune response.

1986 • 51 citations

Regulation of murine B cells through surface immunoglobulin. I. Monoclonal anti-delta antibody that induces allotype-specific proliferation.

1980 • 51 citations

Endotoxin-induced interferon synthesis in macrophage cultures.

1983 • 44 citations

Obligatory role of gamma interferon in T cell-replacing factor-dependent, antigen-specific murine B cell responses.

1985 • 43 citations

Effect of mouse genotype on interferon production

1979 • 29 citations

Interleukin 4 inhibits the interleukin 2-induced production of its functional antagonist, interferon gamma

1989 • 19 citations

Polyclonal activation of the murine immune system by an antibody to IgD. VIII. Stimulation of IgD secretion.

1987 • 16 citations

THE INTERFERON INDUCER FROM BRUCELLA

1970 • 15 citations