Oscillations in Oxygen Consumption by Permeabilized Clonal Pancreatic β-Cells (HIT) Incubated in an Oscillatory Glycolyzing Muscle Extract: Roles of Free Ca2+, Substrates, and the ATP/ADP Ratio

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

1990 • 3,250 citations

Role of calcium ions in regulation of mammalian intramitochondrial metabolism

1990 • 1,369 citations

Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion

1987 • 773 citations

Impaired Pulsatile Secretion of Insulin in Relatives of Patients with Non-Insulin-Dependent Diabetes

1988 • 530 citations

Oscillatory Phenomena in Biochemistry

1971 • 486 citations

Are the β-Cell Signaling Molecules Malonyl-CoA and Cystolic Long-Chain Acyl-CoA Implicated in Multiple Tissue Defects of Obesity and NIDDM?

1996 • 466 citations

Single islet beta-cell stimulation by nutrients: relationship between pyridine nucleotides, cytosolic Ca2+ and secretion.

1990 • 265 citations

A versatile time-sharing multichannel spectrophotometer, reflectometer, and fluorometer

1975 • 238 citations

PROPERTIES OF PHOSPHOFRUCTOKINASE FROM RAT LIVER AND THEIR RELATION TO THE CONTROL OF GLYCOLYSIS AND GLUCONEOGENESIS

1965 • 227 citations

Phase relationship of glycolytic intermediates in yeast cells with oscillatory metabolic control

1965 • 222 citations

Oscillations in cytosolic free Ca2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets

1991 • 216 citations

Cooperation of glycolytic enzymes

1969 • 214 citations

Glucose‐induced oscillations of intracellular Ca²⁺ concentration resembling bursting electrical activity in single mouse islets of Langerhans

1989 • 204 citations

High content of mitochondrial glycerol-3-phosphate dehydrogenase in pancreatic islets and its inhibition by diazoxide.

1981 • 189 citations

Glucose-induced oscillations of cytoplasmic Ca2+ in the pancreatic β-cell

1988 • 152 citations

Pulsatility of insulin and glucagon release: physiological significance and pharmacological implications

1987 • 132 citations

Dehydrogenase activation by Ca2+ in cells and tissues

1991 • 131 citations

Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic β-cells

1996 • 121 citations

The purine nucleotide cycle. Control of phosphofructokinase and glycolytic oscillations in muscle extracts

1975 • 108 citations

Control of phosphofructokinase from rat skeletal muscle. Effects of fructose diphosphate, AMP, ATP, and citrate.

1976 • 105 citations

Two sites for adenine-nucleotide regulation of ATP-sensitive potassium channels in mouse pancreatic ?-cells and HIT cells

1992 • 100 citations

Pulsatile Secretion of Fuel-Regulatory Hormones

1987 • 99 citations

The Purine Nucleotide Cycle

1974 • 98 citations

Metabolic Control Phenomena Involved in Damped Sinusoidal Oscillations of Reduced Diphosphopyridine Nucleotide in a Cell-free Extract of Saccharomyces carlsbergensis

1965 • 98 citations

Three types of cytoplasmic Ca2+ oscillations in stimulated pancreatic β-cells

1989 • 89 citations

Acyl-CoA esters modulate intracellular Ca2+ handling by permeabilized clonal pancreatic beta-cells.

1992 • 87 citations

Linked oscillations of free Ca2+ and the ATP/ADP ratio in permeabilized RINm5F insulinoma cells supplemented with a glycolyzing cell-free muscle extract.

1988 • 84 citations

Regulation of pancreatic β-cell mitochondrial metabolism: influence of Ca2+, substrate and ADP

1996 • 84 citations

Phosphofructokinase Isozymes in Pancreatic Islets and Clonal β-Cells (INS-1)

1995 • 81 citations

Regulation of mitochondrial glycerol-phosphate dehydrogenase by Ca2+ within electropermeabilized insulin-secreting cells (INS-1)

1992 • 74 citations

Glucose-induced activation of pyruvate dehydrogenase in isolated rat pancreatic islets

1990 • 70 citations

Nature of the subunits of the 6-phosphofructo-1-kinase isoenzymes from rat tissues

1987 • 67 citations

The Purine Nucleotide Cycle

1973 • 63 citations

Temporal sequence of metabolic and ionic events in glucose-stimulated clonal pancreatic β-cells (HIT)

1996 • 60 citations

Isolation and characterization of phosphofructokinase C from rabbit brain.

1985 • 56 citations

Regulation of steady-state free Ca2+ levels by the ATP/ADP ratio and orthophosphate in permeabilized RINm5F insulinoma cells.

1988 • 51 citations

Activation of muscle phosphofructokinase by fructose 2,6-bisphosphate and fructose 1,6-bisphosphate is differently affected by other regulatory metabolites.

1985 • 49 citations

Control of reduced diphosphopyridine nucleotide oscillations in beef heart extracts

1968 • 47 citations

Fructose 2,6-bisphosphate and glycolytic oscillations in skeletal muscle extracts.

1988 • 45 citations

Oscillations of nucleotides and glycolytic intermediates in aerobic suspensions of Ehrlich ascites tumor cells

1967 • 42 citations

Modulation by citrate of glycolytic oscillations in skeletal muscle extracts

1991 • 35 citations

Oscillatory synthesis of glucose 1,6-bisphosphate and frequency modulation of glycolytic oscillations in skeletal muscle extracts.

1990 • 29 citations

Analysis of the dynamics of relaxation type oscillation in glycolysis of yeast extracts

1991 • 23 citations

Calcium Activation of Pancreatic Islet Mitochondrial Glycerol Phosphate Dehydrogenase

1982 • 21 citations

Specific Enzymatic Spectrophotometric Assay of Adenosine 5′-Diphosphate

1993 • 1 citations