The influence of serum components on the growth and mutation of Chinese hamster cells in medium containing 8-azaguanine

Mammalian cell genetics. II. Chemical induction of specific locus mutations in Chinese hamster cells in vitro.

1968 • 376 citations

Cell and Tissue Culture

1971 • 366 citations

The use of drug-resistant markers to study the hybridization of mouse fibroblasts

1966 • 326 citations

8-AZAGUANINE RESISTANCE IN MAMMALIAN CELLS I. HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE

1972 • 273 citations

Transfer of Genetic Information by Purified Metaphase Chromosomes

1973 • 236 citations

Chapter 7: Isolation of Mutants of Cultured Mammalian Cells

1973 • 232 citations

Resistance of cultured human fibroblasts and other cells to purine and pyrimidine analogues in relation to mutagenesis detection

1974 • 174 citations

METABOLIC REGULATORY CIRCUITS AND CARCINOGENESIS.

1963 • 172 citations

Mutagenicity to Mammalian Cells of Epoxides and Other Derivatives of Polycyclic Hydrocarbons

1971 • 172 citations

Mutation rates in cells at different ploidy levels

1971 • 171 citations

THE INOSINIC ACID PYROPHOSPHORYLASE ACTIVITY OF MOUSE FIBROBLASTS PARTIALLY RESISTANT TO 8-AZAGUANINE

1963 • 161 citations

The spontaneous azaguanine-resistant mutants of diploid human fibroblasts

1972 • 161 citations

Altered Enzymes in Drug-Resistant Variants of Mammalian Tissue Culture Cells

1973 • 158 citations

Mutations Affecting the Structure of Hypoxanthine: Guanine Phosphoribosyltransferase in Cultured Chinese Hamster Cells

1973 • 139 citations

Mutagenesis of cultured mammalian cells by X-irradiation and ultraviolet light

1970 • 110 citations

Effect of Ploidy and Mutagens on Bromodeoxyuridine Resistance in Haploid and Diploid Frog Cells

1972 • 94 citations

The mutagenicity to mammalian cells of pyrimidine nucleoside analogs

1972 • 86 citations

Mutant chinese hamster cells with a thermosensitive hypoxanthine-guanine phosphoribosyltransferase

1975 • 83 citations

The role of metabolic cooperation in selection of hypoxanthine-guanine-phosphoribosyl-transferase (HG-PRT)-deficient mutants from diploid mammalian cell strains

1972 • 82 citations

Enhancement by caffeine of N-methyl-N-nitrosourea-induced mutations and chromosome aberrations in chinese hamster cells

1973 • 79 citations

Induction and Analysis of Gene Mutations in Mammalian Cells in Culture

1971 • 78 citations

The induction of azaguanine-resistant mutants in cultured Chinese hamster cells by reactive derivatives of carcinogenic hydrocarbons.

1973 • 76 citations

Genetics of Human Cell Lines I. 8-Azaguanine Resistance, a Selective "Single-Step" Marker.

1959 • 74 citations

REQUIREMENT FOR CELL DISPERSION PRIOR TO SELECTION OF INDUCED AZAGUANINE-RESISTANT COLONIES OF CHINESE HAMSTER CELLS

1975 • 68 citations

Immunological characterization of hypoxanthine‐guanine phosphoribosyl transferase mutants of mouse L cells: Evidence for mutations at different loci in the HGPRT gene

1975 • 67 citations

Prevention of Toxicity of Amethopterin for Sarcoma-180 Cells in Tissue Culture

1957 • 61 citations

Factors affecting the quantitation of dose-response curves for mutation induction in V79 Chinese hamster cells after exposure to chemical and physical mutagens

1975 • 57 citations

Detection of females heterozygous for the Lesch-Nyhan mutation by 8-azaguanine-resistant growth of cultured fibroblasts.

1971 • 47 citations

Application of the isotope-dilution principle to the analysis of factors affecting the incorporation of [3H]uridine and [3H]cytidine into cultured lymphocytes. Evaluation of pools in serum and culture media

1971 • 43 citations

Hypoxanthine-Guanine Phosphoribosyltransferase Variant Associated with Accelerated Purine Synthesis

1973 • 41 citations

The effect of calf serum on the toxicity of 8-azaguanine

1975 • 40 citations

Azaguanine resistant hamster cell lines not deficient in hypoxanthine‐guanine phosphoribosyl transferase

1973 • 37 citations

Selection of Biochemically Variant, in Some Cases Mutant, Mammalian Cells in Culture

1975 • 36 citations

Cells with Phosphoribosyl Transferase Activity recovered from Mouse Cells resistant to 8-Azaguanine

1973 • 33 citations

The uptake of deoxyribonucleic acid released from damaged cells in tissue cultures

1967 • 25 citations

Reversion of the 8-azaguanine resistant phenotype of variant Chinese hamster cells treated with alkylating agents and 5-bromo-2′-deoxyuridine

1975 • 24 citations

The effect of variable serum factors and clonal morphology on the ability to detect hypoxanthine guanine phosphoribosyl transferase (HPRT) deficient variants in cultured Chinese hamster cells

1975 • 23 citations

DNA-mediated transformation of mammalian cells in culture. Increased transforming efficiency following sonication

1970 • 20 citations

Serum effect on the yield of chemically induced 8-azaguanine-resistant mutants in Chinese hamster cell cultures

1974 • 20 citations

The influence of serum components on the growth and mutation of Chinese hamster cells in medium containing aminopterin

1974 • 19 citations

Differential sensitivity of human normal and malignant cells to 8-azahypoxanthine in vitro

1971 • 17 citations

Cytotoxicity, mutations and DNA damage produced in Chinese hamster cells treated with streptozotocin, its analogs, and N-methyl-N′-nitro-N-nitrosoguanidine

1976 • 16 citations

A method for determining plasma levels of oxypurines

1970 • 16 citations