Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

INTERFERONS AND THEIR ACTIONS

1987 • 1,838 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.

1981 • 1,048 citations

Expression of a Bacterial Gene in Mammalian Cells

1980 • 788 citations

Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells

1984 • 729 citations

Characterization of a newly derived human sarcoma cell line (HT-1080)

1974 • 681 citations

Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control.

1988 • 583 citations

Fluorescence-activated cell analysis and sorting of viable mammalian cells based on beta-D-galactosidase activity after transduction of Escherichia coli lacZ.

1988 • 487 citations

Promoters, activator proteins, and the mechanism of transcriptional initiation in yeast

1987 • 476 citations

Interferon response element of the human gene 6-16.

1988 • 292 citations

High-affinity binding of 125I-labelled mouse interferon to a specific cell surface receptor

1980 • 275 citations

Hygromycin B phosphotransferase as a selectable marker for DNA transfer experiments with higher eucaryotic cells.

1984 • 258 citations

The new yeast genetics

1983 • 200 citations

Interferon-induced binding of nuclear factors to promoter elements of the 2-5A synthetase gene.

1988 • 190 citations

Enhancer-like interferon responsive sequences of the human and murine (2′-5′) oligoadenylate synthetase gene promoters.

1988 • 188 citations

Interferon-stimulated transcription: isolation of an inducible gene and identification of its regulatory region.

1986 • 185 citations

Comparison of the Antiviral Activities of Various Cloned Human Interferon- Subtypes in Mammalian Cell Cultures

1981 • 164 citations

Detection of deletion mutations in pSV2gpt-transformed cells.

1984 • 134 citations

Overlapping sites for constitutive and induced DNA binding factors involved in interferon-stimulated transcription.

1989 • 134 citations

Interferon and Cell Division. IX. Interferon-Resistant L1210 Cells: Characteristics and Origin2

1974 • 132 citations

125I-labelled Human Interferons Alpha, Beta and Gamma: Comparative Receptor-binding Data

1985 • 123 citations

Differential regulation of interferon‐induced mRNAs and c‐myc mRNA by α‐ and γ‐interferons

1985 • 110 citations

Binding of ¹²⁵I‐labelled human αinterferon to human lymphoid cells

1981 • 109 citations

Characterization of a human gene inducible by alpha- and beta-interferons and its expression in mouse cells.

1986 • 104 citations

Loss of mouse chromosomes in somatic cell hybrids between HT-1080 human fibrosarcoma cells and mouse peritioneal macrophages.

1976 • 98 citations

The molecular nature of mutations in cultured mammalian cells: A review

1985 • 95 citations

Hygromycin B Phosphotransferase as a Selectable Marker for DNA Transfer Experiments with Higher Eucaryotic Cells

1984 • 94 citations

Molecular cell genetics

1986 • 93 citations

Interferons And Their Actions

1987 • 91 citations

Analyses of mutation in pSV2gpt-transformed CHO cells

1986 • 87 citations

Cells resistant to interferon are defective in activation of a promoter-binding factor.

1988 • 83 citations

Transcriptional regulation of interferon-responsive genes is closely linked to interferon receptor occupancy.

1986 • 78 citations

Isolation of interferon-resistant variants of friend erythroleukemia cells: Effects of interferon and ouabain

1982 • 73 citations

Sequence analysis of spontaneous mutations in a shuttle vector gene integrated into mammalian chromosomal DNA.

1987 • 72 citations

Modulation of transfected gene expression mediated by changes in chromatin structure

1982 • 72 citations

Specific high-affinity binding of 125I-labeled mouse interferon to interferon resistant embryonal carcinoma cells in vitro

1981 • 64 citations

Characterization and regulation of alpha-interferon receptor expression in interferon-sensitive and -resistant human lymphoblastoid cells.

1984 • 63 citations

Analysis and Purification of Human Lymphoblastoid (Namalwa) Interferon Using a Monoclonal Antibody

1982 • 60 citations

Differential binding of human interferon-α subtypes to receptors on lymphoblastoid cells

1983 • 57 citations

Spontaneous and ICR191-A-induced Frameshift Mutations in the A Gene of Escherichia coli Tryptophan Synthetase

1968 • 55 citations

Binding of human interferon alpha to cells of different sensitivities: studies with internally radiolabeled interferon retaining full biological activity

1983 • 53 citations

Phenotypic Switching in Cells Transformed with the Herpes Simplex Virus Thymidine Kinase Gene

1982 • 52 citations

Model involving gene inactivation in the generation of autosomal recessive mutants in mammalian cells in culture.

1982 • 45 citations

The nature of mutants induced by ionizing radiation in cultured hamster cells

1986 • 44 citations

Isolation of Daudi Cells with Reduced Sensitivity to Interferon. II. On The Mechanisms of Resistance

1983 • 43 citations

The use of a cloned bacterial gene to study mutation in mammalian cells

1983 • 41 citations

Isolation of Daudi Cells with Reduced Sensitivity to Interferon.: I. Characterization

1983 • 39 citations

Comparative mutagenicity of ICR-191 to S. typhimurium and diploid human lymphoblasts

1977 • 33 citations

The nature of mutants by ionising radiation in cultured hamster cells

1984 • 31 citations

Phenotypic Switching in Cells Transformed with the Herpes Simplex Virus Thymidine Kinase Gene

1982 • 28 citations

A New Genetic Approach for Studying Hormonal Regulation of Urokinase-Type Plasminogen Activator Gene Expression in LLC-PK₁ Cells

1987 • 16 citations

Chromosome-mediated gene transfer of HPRT and APRT in an intraspecific human cell system

1983 • 12 citations

Model Involving Gene Inactivation in the Generation of Autosomal Recessive Mutants in Mammalian Cells in Culture

1982 • 10 citations

Epitopes of human interferon-alpha defined by the reaction of monoclonal antibodies with alpha interferons and interferon analogues.

1987 • 8 citations

A new genetic approach for studying hormonal regulation of urokinase-type plasminogen activator gene expression in LLC-PK1 cells.

1987 • 4 citations