Insulin-like growth factor I is required for vessel remodeling in the adult brain

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies

2013 • 8,227 citations

Insulin-Like Growth Factors and Their Binding Proteins: Biological Actions*

1995 • 4,419 citations

Stereological Methods. Practical methods for biological morphometry

1979 • 2,038 citations

HIF-1: mediator of physiological and pathophysiological responses to hypoxia

2000 • 1,769 citations

Normal growth and development in the absence of hepatic insulin-like growth factor I

1999 • 1,430 citations

Learning causes synaptogenesis, whereas motor activity causes angiogenesis, in cerebellar cortex of adult rats.

1990 • 1,142 citations

Circulating Insulin-Like Growth Factor I Mediates Exercise-Induced Increases in the Number of New Neurons in the Adult Hippocampus

2001 • 976 citations

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

1999 • 938 citations

p42/p44 Mitogen-activated Protein Kinases Phosphorylate Hypoxia-inducible Factor 1α (HIF-1α) and Enhance the Transcriptional Activity of HIF-1

1999 • 777 citations

Circulating Insulin-Like Growth Factor I Mediates Effects of Exercise on the Brain

2000 • 734 citations

Circulating Insulin-Like Growth Factor I Mediates the Protective Effects of Physical Exercise against Brain Insults of Different Etiology and Anatomy

2001 • 593 citations

Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor

1999 • 560 citations

The role of the insulin-like growth factors in the central nervous system

1996 • 443 citations

Serum insulin-like growth factor I regulates brain amyloid-β levels

2002 • 440 citations

Mechanisms of Angiogenesis in the Brain

1999 • 352 citations

Oxygen sensors and angiogenesis

2002 • 323 citations

Decreases in Cerebral Microvasculature with Age Are Associated with the Decline in Growth Hormone and Insulin-Like Growth Factor 1*

1997 • 286 citations

Co-ordinated and cellular specific induction of the components of the IGF/IGFBP axis in the rat brain following hypoxic–ischemic injury

1998 • 197 citations

IGF-I Is Critical for Normal Vascularization of the Human Retina

2002 • 192 citations

Regulation of Vascular Endothelial Growth Factor Expression by Insulin-Like Growth Factor I

1997 • 182 citations

Culture and characterization of microvascular endothelial cells derived from human brain.

1991 • 164 citations

Stimulatory effects of insulin and insulin-like growth factor I on migration and tube formation by vascular endothelial cells

1992 • 153 citations

Insulin-like growth factors and insulin-like growth factor binding proteins in cerebrospinal fluid and serum of patients with dementia of the Alzheimer type

1993 • 145 citations

Localization of insulin-like growth factor binding protein-2 messenger RNA during postnatal brain development: Correlation with insulin-like growth factors I and II

1993 • 133 citations

Localization of the insulin-like growth factor I receptor in the cerebellum and hypothalamus of adult rats: an electron microscopic study.

1997 • 121 citations

Insulin-Like Growth Factors as Mediators of Functional Plasticity in the Adult Brain

1999 • 114 citations

Spatial and Temporal Changes in the Insulin-Like Growth Factor (IGF) Axis Indicate Autocrine/Paracrine Actions of IGF-I within Wounds of the Rat Brain*

1997 • 110 citations

Trophic effects of insulin-like growth factor-I on fetal rat hypothalamic cells in culture

1990 • 109 citations

Serum Growth Factors and Neuroprotective Surveillance

2000 • 104 citations

Insulin-like Growth Factor-I Stimulates Dephosphorylation of IκB through the Serine Phosphatase Calcineurin (Protein Phosphatase 2B)

2000 • 95 citations

Plasma Insulin-like Growth Factor I and IGF Binding Protein 3 Levels in Patients With Acute Cerebral Ischemic Injury

1997 • 91 citations

Microspheres containing insulin-like growth factor I for treatment of chronic neurodegeneration

2003 • 51 citations

Insulin-like growth factor I stimulate angiogenesis and the production of vascular endothelial growth factor

2000 • 47 citations

Effects of insulin‐like growth factor‐1 on retinal endothelial cell glucose transport and proliferation

2001 • 36 citations

Surface‐weighted star volume: concept and estimation

1998 • 34 citations