A Mechanistic Study to Assess Whether Isoproterenol Can Reverse the Negative Chronotropic Effect of Fingolimod

Oral Fingolimod (FTY720) for Relapsing Multiple Sclerosis

2006 • 1,043 citations

Sphingosine 1-phosphate receptors in health and disease: Mechanistic insights from gene deletion studies and reverse pharmacology

2007 • 524 citations

Signaling and biological actions of sphingosine 1-phosphate

2003 • 272 citations

FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity

2002 • 265 citations

Molecular and Cellular Diversity of Neuronal G-Protein-Gated Potassium Channels

2005 • 198 citations

Immunomodulator FTY720 Induces eNOS-Dependent Arterial Vasodilatation via the Lysophospholipid Receptor S1P ₃

2005 • 122 citations

FTY720: Placebo‐Controlled Study of the Effect on Cardiac Rate and Rhythm in Healthy Subjects

2006 • 111 citations

FTY720, an immunomodulatory sphingolipid mimetic: translation of a novel mechanism into clinical benefit in multiple sclerosis

2007 • 93 citations

Single‐dose FTY720 pharmacokinetics, food effect, and pharmacological responses in healthy subjects

2004 • 80 citations

Handbook of emergency cardiovascular care for healthcare providers

2006 • 72 citations

Effects of sphingosine 1-phosphate on pacemaker activity in rabbit sino-atrial node cells

1999 • 70 citations

Ethnic sensitivity study of fingolimod in white and Asian subjects

2007 • 24 citations

FTY720 Pharmacokinetics in Mild to Moderate Hepatic Impairment

2005 • 18 citations