Evidence for an Underlying CD4 Helper and CD8 T-Cell Defect in B-Cell-Deficient Mice: Failure To Clear Persistent Virus Infection after Adoptive Immunotherapy with Virus-Specific Memory Cells from μMT/μMT Mice

Reconstitution of Cellular Immunity against Cytomegalovirus in Recipients of Allogeneic Bone Marrow by Transfer of T-Cell Clones from the Donor

1995 • 1,828 citations

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

1991 • 1,783 citations

Antiviral pressure exerted by HIV-l-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

1997 • 1,206 citations

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

1994 • 1,161 citations

Intracellular Inactivation of the Hepatitis B Virus by Cytotoxic T Lymphocytes

1996 • 1,085 citations

Antitrinitrophenyl (TNP) Plaque Assay. Primary Response of Balb/c Mice to Soluble and Particulate Immunogen

1969 • 935 citations

Visualization of Specific B and T Lymphocyte Interactions in the Lymph Node

1998 • 762 citations

Cytotoxic T-lymphocyte response to cytomegalovirus after human allogeneic bone marrow transplantation: pattern of recovery and correlation with cytomegalovirus infection and disease

1991 • 686 citations

The Virology and Immunobiology of Lymphocytic Choriomeningitis Virus Infection

1980 • 554 citations

B cells inhibit induction of T cell-dependent tumor immunity

1998 • 393 citations

Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice

1994 • 321 citations

Viral Persistence in Neurons Explained by Lack of Major Histocompatibility Class I Expression

1991 • 308 citations

CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response.

1996 • 300 citations

Cytotoxic T lymphocyte responsiveness after resolution of chronic hepatitis B virus infection.

1996 • 299 citations

Virus-induced immunosuppression: immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression

1995 • 289 citations

CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge

1996 • 287 citations

Cytoimitiunotherapy for persistent virus infection reveals a unique clearance pattern from the central nervous system

1986 • 250 citations

Genomic and Biological Variation among Commonly Used Lymphocytic Choriomeningitis Virus Strains

1983 • 241 citations

A Modification of the Hemolytic Plaque Assay for Use with Protein Antigens

1968 • 219 citations

Quantitation and Cloning of Cytolytic T Lymphocytes and their Precursors

1980 • 213 citations

A critical role for neutralizing-antibody-producing B cells, CD4⁺T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: Implications for adoptive immunotherapy of virus carriers

1997 • 202 citations

Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virus-infected MHC class II-deficient mice and B cell-deficient mice.

1996 • 185 citations

Endogenous IL-2 contributes to T cell expansion and IFN-gamma production during lymphocytic choriomeningitis virus infection.

1995 • 172 citations

Fine dissection of a nine amino acid glycoprotein epitope, a major determinant recognized by lymphocytic choriomeningitis virus-specific class I-restricted H-2Db cytotoxic T lymphocytes.

1988 • 166 citations

CD8 T cell memory in B cell-deficient mice.

1996 • 158 citations

Analyses of the cytotoxic T lymphocyte responses to glycoprotein and nucleoprotein components of lymphocytic choriomeningitis virus

1988 • 155 citations

An Essential Role for Type 1 Interferon-γ in Terminating Persistent Viral Infection

1995 • 145 citations

PREPARATION OF PURIFIED ANTI-2,4-DINITROPHENYL ANTIBODIES.

1964 • 141 citations

Immunological memory

1997 • 124 citations

Virus-lymphocyte interactions IV. Molecular characterization of LCMV Armstrong (CTL+) small genomic segment and that of its variant, clone 13 (CTL−)

1988 • 118 citations

CD4+ T cell activation and tolerance induction in B cell knockout mice.

1996 • 103 citations

Immunity to viruses in B cell‐deficient mice: Influence of antibodies on virus persistence and on T cell memory

1996 • 100 citations

Abortive Proliferation of Rare T Cells Induced by Direct or Indirect Antigen Presentation by Rare B Cells In Vivo

1998 • 88 citations

Mechanisms of antibody-mediated protection against lymphocytic choriomeningitis virus infection: mother-to-baby transfer of humoral protection

1992 • 85 citations

Immune therapy of a persistent and disseminated viral infection

1987 • 77 citations

Effective clearance of a persistent viral infection requires cooperation between virus-specific Lyt2+ T cells and nonspecific bone marrow-derived cells

1987 • 76 citations

Virus-lymphocyte interactions

1978 • 74 citations

The Role of CD4⁺ T Cells in Cell‐Mediated Immunity to LCM V: Studies in MHC Class I and Class II Deficient Mice

1994 • 71 citations

Infection of lymphocytes by a virus that aborts cytotoxic T lymphocyte activity and establishes persistent infection.

1991 • 71 citations

Virus-Induced Immune Complex Disease: Identification of Specific Viral Antigens and Antibodies Deposited in Complexes during Chronic Lymphocytic Choriomeningitis Virus Infection

1978 • 70 citations

In vivo induction of tolerance in murine CD4+ cell subsets.

1993 • 68 citations

B‐T Lymphocyte Interactions in the Generation and Survival of Memory Cells

1996 • 68 citations

A simple method for evaluating the rejection of grafted spleen cells by flow cytometry and tracing adoptively transferred cells by light microscopy

1997 • 64 citations

Antiviral antibodies attenuate T-cell-mediated immunopathology following acute lymphocytic choriomeningitis virus infection

1991 • 58 citations

STUDIES ON IMMUNOLOGICAL TOLERANCE TO LCM VIRUS

1963 • 57 citations

TWO POPULATIONS OF T LYMPHOCYTES IMMUNE TO THE LYMPHOCYTIC CHORIOMENINGITIS VIRUS

1974 • 53 citations

Role of B-cell and Fc receptors in the selection of T-cell epitopes

1998 • 48 citations

Cytotoxic T Lymphocytes Cleanse Viral Gene Products from Individually Infected Neurons and Lymphocytes in Mice Persistently Infected with Lymphocytic Choriomeningitis Virus

1993 • 46 citations

Bacterial lipopolysaccharide (endotoxin) interferes with the induction of tolerance and primes thymus-derived lymphocytes.

1981 • 34 citations

Lack of B-cell participation in acute lymphocyte choriomeningitis disease of the central nervous system

1978 • 33 citations

STUDIES ON IMMUNOLOGICAL TOLERANCE TO LCM VIRUS

1965 • 30 citations

The activity of T and B lymphocytes in immunity and tolerance to the lymphocytic choriomeningitis virus in mice.

1975 • 24 citations

Immunity to lymphocytic choriomeningitis virus in B cell‐depleted mice: evidence for B cell and antibody‐independent protection by memory T cells

1986 • 21 citations

Studies on the Role of Mononuclear Phagocytes in Resistance to Acute Lymphocytic Choriomeningitis Virus Infection

1983 • 16 citations

Immunology and Immunity Studied with Viruses

2007 • 10 citations