Constitutive expression of hepatic cytochrome P450 genes

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature

1996 • 2,895 citations

cPLA2 is phosphorylated and activated by MAP kinase

1993 • 1,858 citations

The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary.

1996 • 1,208 citations

Signaling by the cytokine receptor superfamily: JAKs and STATs

1994 • 659 citations

Phenobarbital induction of cytochrome P-450 gene expression

1992 • 530 citations

Evolution of the P450 gene superfamily:

1990 • 508 citations

The AH-receptor: genetics, structure and function

1993 • 437 citations

Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme.

1986 • 408 citations

Induction of Rat Hepatic N-Nitrosodimethylamine Demethylase by Acetone Is Due to Protein Stabilization

1989 • 277 citations

Intermittent Plasma Growth Hormone Triggers Tyrosine Phosphorylation and Nuclear Translocation of a Liver-Expressed, Stat 5-related DNA Binding Protein.

1995 • 242 citations

Signaling by Receptor Tyrosine Kinases

1993 • 242 citations

The human CYP1A2 gene and induction by 3-methylcholanthrene. A region of DNA that supports AH-receptor binding and promoter-specific induction.

1994 • 178 citations

Repression of HIV-1 Transcription by a Cellular Protein

1991 • 151 citations

The rat P450IIE1 gene: complete intron and exon sequence, chromosome mapping, and correlation of developmental expression with specific 5' cytosine demethylation.

1988 • 134 citations

Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1.

1991 • 133 citations

Transcriptional control in hepatocytes: a window on development

1991 • 128 citations

Regulation of sexual differentiation in drug and steroid metabolism

1989 • 124 citations

Regulation of cytochrome P450 genes: molecular mechanisms

1993 • 99 citations

Transcriptional control of the rat hepatic CYP2E1 gene.

1990 • 95 citations

Sex change in cytochrome P-450 phenotype by growth hormone treatment of adult rat hepatocytes maintained in a culture system on matrigel.

1988 • 95 citations

Transcriptional activators in hepatocytes.

1990 • 90 citations

Multiple, functional DBP sites on the promoter of the cholesterol 7 alpha-hydroxylase P450 gene, CYP7. Proposed role in diurnal regulation of liver gene expression.

1994 • 82 citations

A STAT Factor Mediates the Sexually Dimorphic Regulation of Hepatic Cytochrome P450 3A10/Lithocholic Acid 6β-Hydroxylase Gene Expression by Growth Hormone

1995 • 65 citations

A transcriptional regulatory element common to a large family of hepatic cytochrome P450 genes is a functional binding site of the orphan receptor HNF-4.

1994 • 62 citations

Sexually dimorphic DNA demethylation in the promoter of the Slp (sex-limited protein) gene in mouse liver.

1995 • 59 citations

A Nuclear Factor (NF2d9) That Binds to the Male-Specific P450 (Cyp 2d-9) Gene in Mouse Liver

1995 • 55 citations

Transcriptional regulatory elements for basal expression of cytochrome P450IIC genes.

1992 • 39 citations

[34] Analysis of methylation and chromatin structure

1993 • 36 citations

Role of the Liver-Enriched Transcription Factor DBP in Expression of the Cytochrome P450 CYP2C6 Gene

1992 • 36 citations

Growth Hormone Signaling Leading to CYP2C12 Gene Expression in Rat Hepatocytes Involves Phospholipase A2

1995 • 35 citations

Characterization of a rabbit gene encoding a clofibrate-inducible fatty acid ω-hydroxylase: CYP4A6

1992 • 26 citations

Differential Protein Binding and Transcriptional Activities of HNF-4 Elements in Three Closely RelatedCYP2CGenes

1994 • 23 citations

A specific cis-acting element regulates in vitro transcription of sex-dependent mouse steroid 16 alpha-hydroxylase (C-P450(16 alpha)) gene.

1990 • 21 citations

Specific Cytosine Demethylations within the First Exons of the RatCYP2D3andCYP2D5Genes Are Associated with Activation of Hepatic Gene Expression during Development

1990 • 20 citations

Hepatocyte nuclear factor 3 is a major determinant of CYP2C6 promoter activity in hepatoma cells.

1994 • 18 citations