The Importance of Exogenous Antigen in Priming the Human CD8+ T Cell Response: Lessons from the EBV Nuclear Antigen EBNA1

Dendritic cells and the control of immunity

1998 • 14,345 citations

Phenotypic Analysis of Antigen-Specific T Lymphocytes

1996 • 3,611 citations

T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

1998 • 2,615 citations

Epstein-Barr Virus

1986 • 2,255 citations

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

1998 • 2,106 citations

MHC ligands and peptide motifs: first listing

1995 • 1,674 citations

Antigen-specific interaction between T and B cells

1985 • 1,396 citations

Immature Dendritic Cells Phagocytose Apoptotic Cells via αvβ5 and CD36, and Cross-present Antigens to Cytotoxic T Lymphocytes

1998 • 1,226 citations

MECHANISMS OF MHC CLASS I–RESTRICTED ANTIGEN PROCESSING

1998 • 1,017 citations

Direct Visualization of Antigen-specific CD8+T Cells during the Primary Immune Response to Epstein-Barr Virus In Vivo

1998 • 902 citations

Inhibition of antigen processing by the internal repeat region of the Epstein–Barr virus nuclear antigen-1

1995 • 820 citations

Viral Strategies of Immune Evasion

1998 • 791 citations

HUMAN CYTOTOXIC T LYMPHOCYTE RESPONSES TO EPSTEIN-BARR VIRUS INFECTION

1997 • 769 citations

Induction of a CD8+ Cytotoxic T Lymphocyte Response by Cross-priming Requires Cognate CD4+ T Cell Help

1997 • 729 citations

Rapid Effector Function in CD8+ Memory T Cells

1997 • 652 citations

Molecular analysis of the association of HLA-B53 and resistance to severe malaria

1992 • 645 citations

Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen

1999 • 586 citations

Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein–Barr virus nuclear antigen 1

1997 • 549 citations

Identification of target antigens for the human cytotoxic T cell response to Epstein-Barr virus (EBV): implications for the immune control of EBV-positive malignancies.

1992 • 519 citations

Localization of Epstein-Barr virus cytotoxic T cell epitopes using recombinant vaccinia: implications for vaccine development.

1992 • 402 citations

Constitutive macropinocytosis allows TAP‐dependent major histocompatibility compex class I presentation of exogenous soluble antigen by bone marrow‐derived dendritic cells

1997 • 351 citations

Human Cd4+ T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus Nuclear Antigen Ebna1

2000 • 340 citations

Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis.

1995 • 300 citations

Mechanisms of Exogenous Antigen Presentation by MHC Class I Molecules in Vitro and in Vivo: Implications for Generating CD8+ T Cell Responses to Infectious Agents, Tumors, Transplants, and Vaccines

1999 • 293 citations

Human CD8 + T Cell Responses to EBV EBNA1: HLA Class I Presentation of the (Gly-Ala)–Containing Protein Requires Exogenous Processing

1997 • 261 citations

Clonal transformation of adult human leukocytes by Epstein-Barr virus

1977 • 213 citations

Antibody responses to Epstein-Barr virus-determined nuclear antigen (EBNA)-1 and EBNA-2 in acute and chronic Epstein-Barr virus infection.

1987 • 202 citations

Antibodies to Epstein-Barr Virus-Associated Nuclear Antigen in Infectious Mononucleosis

1974 • 180 citations

Identification of cytotoxic T cell epitopes within Epstein-Barr virus (EBV) oncogene latent membrane protein 1 (LMP1): evidence for HLA A2 supertype-restricted immune recognition of EBV-infected cells by LMP1-specific cytotoxic T lymphocytes

1998 • 177 citations

Epitope focusing in the primary cytotoxic T cell response to Epstein-Barr virus and its relationship to T cell memory.

1996 • 171 citations

Bound Water Structure and Polymorphic Amino Acids Act Together to Allow the Binding of Different Peptides to MHC Class I HLA-B53

1996 • 162 citations

An Altered Position of the α2 Helix of MHC Class I Is Revealed by the Crystal Structure of HLA-B*3501

1996 • 160 citations

Cytotoxic T lymphocyte activation by cross-priming

1999 • 108 citations

Cytomegaloviral control of MHC class I function in the mouse

1999 • 107 citations

Cytokines restore MHC class I complex formation and control antigen presentation in human cytomegalovirus-infected cells

1995 • 83 citations

Immunodominance Among EBV-Derived Epitopes Restricted by HLA-B27 Does Not Correlate with Epitope Abundance in EBV-Transformed B-Lymphoblastoid Cell Lines

2000 • 80 citations

Identification of EBNA1 amino acid sequences required for the interaction of the functional elements of the Epstein-Barr virus latent origin of DNA replication

1993 • 70 citations

Sequential appearance of Epstein–Barr virus nuclear and lymphocyte-detected membrane antigens in B cell transformation

1981 • 58 citations

Nonresponsiveness to an immunodominant Epstein-Barr virus-encoded cytotoxic T-lymphocyte epitope in nuclear antigen 3A: implications for vaccine strategies.

1991 • 32 citations

Murine Cytotoxic T Lymphocytes Recognize an Epitope in an EBNA-1 Fragment, but Fail to Lyse EBNA-1–expressing Mouse Cells

1998 • 29 citations

Mechanisms of MHC class I-restricted antigen presentation

2001 • 9 citations