Nonresponsiveness to an immunodominant Epstein-Barr virus-encoded cytotoxic T-lymphocyte epitope in nuclear antigen 3A: implications for vaccine strategies.

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

1985 • 1,650 citations

Antigen Recognition by Class I-Restricted T Lymphocytes

1989 • 1,207 citations

Cytotoxic T cells recognize fragments of the influenza nucleoprotein

1985 • 669 citations

In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine

1989 • 632 citations

A sequence pattern common to T cell epitopes.

1988 • 623 citations

Biological Activity of Recombinant Human Interleukin-2 Produced in Escherichia coli

1984 • 600 citations

The T Cell Receptor

1987 • 554 citations

T-cell antigenic sites tend to be amphipathic structures.

1985 • 527 citations

Epstein-Barr virus types 1 and 2 differ in their EBNA-3A, EBNA-3B, and EBNA-3C genes

1990 • 490 citations

The evaluation of limiting dilution assays

1982 • 458 citations

U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2.

1984 • 393 citations

Determinant Selection and Macrophage Function in Genetic Control of the Immune Response

1978 • 389 citations

Nature of polymorphism in HLA-A, -B, and -C molecules.

1988 • 379 citations

Site-Specific Mutagenesis of the Human Interleukin-2 Gene: Structure-Function Analysis of the Cysteine Residues

1984 • 328 citations

Geographical prevalence of two types of Epstein-Barr virus

1986 • 290 citations

Is T-cell memory maintained by crossreactive stimulation?

1990 • 253 citations

Peptide-induced antiviral protection by cytotoxic T cells.

1991 • 238 citations

A membrane protein encoded by Epstein-Barr virus in latent growth-transforming infection.

1984 • 226 citations

Long-term T-cell-mediated immunity to Epstein-Barr virus.

1981 • 213 citations

Cytotoxic T-cell clones discriminate between A- and B-type Epstein-Barr virus transformants

1988 • 194 citations

An Epstein-Barr virus-specific cytotoxic T cell epitope in EBV nuclear antigen 3 (EBNA 3).

1990 • 173 citations

A Clonal Deletion Model for Ir Gene Control of the Immune Response

1978 • 156 citations

T Cell Reactivity to MHC Molecules: Immunity Versus Tolerance

1990 • 148 citations

Relative contribution of "determinant selection" and "holes in the T-cell repertoire" to T-cell responses.

1989 • 115 citations

Human cytotoxic T-cell responses against Epstein-Barr virus nuclear antigens demonstrated by using recombinant vaccinia viruses.

1990 • 110 citations

Peptide competition for antigen presentation

1990 • 101 citations

HLA antigen-related restriction of T lymphocyte cytotoxicity to Epstein-Barr virus.

1980 • 100 citations

HLA-DR-antigen-associated restriction of EBV-specific cytotoxic T-cell colonies

1984 • 90 citations

A fifth Epstein-Barr virus nuclear protein (EBNA3C) is expressed in latently infected growth-transformed lymphocytes

1988 • 87 citations

Allelic variations in the human T cell receptor V beta 6.7 gene products.

1990 • 85 citations

Inherited polymorphism of the human T-cell antigen receptor detected by a monoclonal antibody.

1986 • 81 citations

An Epstein-Barr virus-specific cytotoxic T-cell epitope present on A- and B-type transformants

1990 • 80 citations

Murine cytotoxic T lymphocyte recognition of individual influenza virus proteins. High frequency of nonresponder MHC class I alleles.

1988 • 79 citations

Restricted V-segment usage in T-cell receptors from cytotoxic T lymphocytes specific for a major epitope of lymphocytic choriomeningitis virus

1990 • 63 citations

Failure to find holes in the T-cell repertoire

1987 • 51 citations

Expression of Epstein-Barr virus nuclear antigens 3, 4, and 6 are altered in cell lines containing B-type virus

1989 • 44 citations

Recognition of Self and Regulation of Specificity at the Level of Cell Populations

1984 • 39 citations

Predominant utilization of V beta 8+ T cell receptor genes in the H-2Ld-restricted cytotoxic T cell response against the immediate-early protein pp89 of the murine cytomegalovirus.

1989 • 28 citations

Epstein-Barr virus nuclear antigens 1 and 2 in Burkitt lymphoma cell lines containing either 'A'- or 'B'-type virus.

1988 • 20 citations

Induction of Epstein-Barr virus nuclear antigens

1986 • 20 citations

Limiting dilution analysis of memory cytotoxic T lymphocytes specific for individual influenza virus gene products

1988 • 16 citations

Cytotoxic T lymphocyte discrimination between type A Epstein--Barr virus transformants is mapped to an immunodominant epitope in EBNA 3

1991 • 13 citations

Oligopeptide Induction of a Secondary Cytotoxic T‐cell Response to Epstein‐Barr Virus In Vitro

1991 • 3 citations

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