Alveolar Wall Apoptosis Causes Lung Destruction and Emphysematous Changes

Evidence-Based Health Policy—Lessons from the Global Burden of Disease Study

1996 • 2,165 citations

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

2000 • 1,099 citations

A peptide carrier for the delivery of biologically active proteins into mammalian cells

2001 • 984 citations

Lysosomal cysteine proteases: more than scavengers

2000 • 818 citations

EMERGING ROLES FOR CYSTEINE PROTEASES IN HUMAN BIOLOGY

1997 • 767 citations

Endothelial Cell Death and Decreased Expression of Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor 2 in Emphysema

2001 • 687 citations

Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells.

1998 • 646 citations

Cathepsin B Acts as a Dominant Execution Protease in Tumor Cell Apoptosis Induced by Tumor Necrosis Factor

2001 • 626 citations

Human 92- and 72-kilodalton type IV collagenases are elastases.

1991 • 550 citations

Identification of a Novel Hypoxia-Inducible Factor 1-Responsive Gene, RTP801, Involved in Apoptosis

2002 • 515 citations

Upregulation of Gelatinases A and B, Collagenases 1 and 2, and Increased Parenchymal Cell Death in COPD

2000 • 508 citations

Proteolytic Activity of Human Osteoclast Cathepsin K

1996 • 494 citations

CD8 + ve Cells in the Lungs of Smokers with Chronic Obstructive Pulmonary Disease

1999 • 491 citations

Human Cathepsin O2, a Matrix Protein-degrading Cysteine Protease Expressed in Osteoclasts

1996 • 427 citations

The type II epithelial cell of the lung. I. Method of isolation.

1974 • 313 citations

Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages.

1995 • 309 citations

Destructive index: a measurement of lung parenchymal destruction in smokers.

1985 • 223 citations

Chronic Obstructive Pulmonary Disease: Risk Factors, Pathophysiology and Pathogenesis

1989 • 168 citations

Human Cathepsin F

1998 • 164 citations

Metabolic properties and ultrastructure of alveolar type II cells isolated with elastase

1980 • 161 citations

Definitions, Epidemiology, Pathophysiology, Diagnosis, and Staging

1995 • 138 citations

Ultrarapid caspase-3 dependent apoptosis induction by serine/threonine phosphatase inhibitors

1999 • 122 citations

Expression of Cathepsin K in Lung Epithelial Cells

1999 • 85 citations

Type II Pneumocyte–CD8 + T-Cell Interactions

2001 • 26 citations

H2O2 induces apoptosis in bovine tracheal epithelial cells in vitro

1999 • 22 citations