Identification and Cloning of a Connective Tissue Growth Factor-like cDNA from Human Osteoblasts Encoding a Novel Regulator of Osteoblast Functions

Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10.

1991 • 878 citations

Sequence identification of 2,375 human brain genes

1992 • 764 citations

Connective tissue growth factor: a mediator of TGF-β action on fibroblasts

1997 • 743 citations

Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair.

1993 • 706 citations

The modular architecture of a new family of growth regulators related to connective tissue growth factor

1993 • 634 citations

ECM signalling: orchestrating cell behaviour and misbehaviour

1998 • 537 citations

Production of osteocalcin by human bone cells in vitro. Effects of 1,25(OH)2D3, 24,25(OH)2D3, parathyroid hormone, and glucocorticoids

1984 • 500 citations

WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors

1998 • 499 citations

CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth

1998 • 487 citations

Connective Tissue Growth Factor Gene Expression in Tissue Sections From Localized Scleroderma, Keloid, and Other Fibrotic Skin Disorders

1996 • 438 citations

Human Trabecular Bone Cells Are Able to Express Both Osteoblastic and Adipocytic Phenotype: Implications for Osteopenic Disorders

1998 • 359 citations

Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily

1997 • 352 citations

Cyr61, a Product of a Growth Factor-Inducible Immediate-Early Gene, Promotes Cell Proliferation, Migration, and Adhesion

1996 • 339 citations

Identification of a phorbol ester-repressible v-src-inducible gene.

1989 • 322 citations

Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type 1-induced nephroblastomas.

1992 • 311 citations

Cyr61 and Fisp12 Are Both ECM-Associated Signaling Molecules: Activities, Metabolism, and Localization during Development

1997 • 240 citations

ADAMTS-1 Protein Anchors at the Extracellular Matrix through the Thrombospondin Type I Motifs and Its Spacing Region

1998 • 225 citations

Expression of mucin antigens in human cancers and its relationship with malignancy potential

1997 • 204 citations

Structure, mapping, and expression of fisp-12, a growth factor-inducible gene encoding a secreted cysteine-rich protein.

1991 • 203 citations

Purification and Characterization of Novel Heparin-binding Growth Factors in Uterine Secretory Fluids

1997 • 202 citations

Adhesion of Human Umbilical Vein Endothelial Cells to the Immediate-Early Gene Product Cyr61 Is Mediated through Integrin αvβ3

1998 • 202 citations

Human osteoclasts, not osteoblasts, deposit osteopontin onto resorption surfaces: An in vitro and ex vivo study of remodeling bone

1995 • 181 citations

Identification of rCop-1, a New Member of the CCN Protein Family, as a Negative Regulator for Cell Transformation

1998 • 149 citations

Blocking ligand occupancy of the αVβ3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells

1998 • 148 citations

Expression of the growth factor-inducible immediate early gene cyr61 correlates with chondrogenesis during mouse embryonic development.

1992 • 140 citations

Expression of the Elm1 Gene, a Novel Gene of the CCN (Connective Tissue Growth Factor, Cyr61/Cef10, and Neuroblastoma Overexpressed Gene) Family, Suppresses In Vivo Tumor Growth and Metastasis of K-1735 Murine Melanoma Cells

1998 • 138 citations

Characterization of Cell-Associated and Soluble Forms of Connective Tissue Growth Factor (CTGF) Produced by Fibroblast CellsIn Vitro

1998 • 117 citations

Bone Morphogenesis and Modeling: Soluble Signals Sculpt Osteosomes in the Solid State

1997 • 75 citations

Human CYR61-mediated enhancement of bFGF-induced DNA synthesis in human umbilical vein endothelial cells

1998 • 73 citations

Human AT1 receptor is a single copy gene: Characterization in a stable cell line

1994 • 67 citations

The human growth factor-inducible immediate early gene, CYR61, maps to chromosome 1p

1997 • 65 citations

The Human Analog of Murine Cystein Rich Protein 16 Is a 1α,25-Dihydroxyvitamin D3 Responsive Immediate Early Gene in Human Fetal Osteoblasts: Regulation by Cytokines, Growth Factors, and Serum*

1998 • 59 citations

Cathepsin K mRNA Detection Is Restricted to Osteoclasts During Fetal Mouse Development

1998 • 58 citations

Isolation and characterization of xnov, a Xenopus laevis ortholog of the chicken nov gene

1996 • 36 citations

A Novel Human Bone Marrow Stroma-Derived Cell Line TF274 Is Highly Osteogenic In Vitro and In Vivo

1998 • 23 citations

Studies on alpha v beta 3/ligand interactions using a [3H]SK&F-107260 binding assay.

1996 • 14 citations

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