Functional domains of LAG-2, a putative signaling ligand for LIN-12 and GLP-1 receptors in Caenorhabditis elegans.

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Two homologous regulatory genes, lin-12 and glp-1, have overlapping functions

1991 • 252 citations

GLP-1 is localized to the mitotic region of the C. elegans germ line

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lag-1, a gene required for lin-12 and glp-1 signaling in Caenorhabditis elegans, is homologous to human CBF1 and Drosophila Su(H)

1996 • 232 citations

The maternal genes apx-1 and glp-1 and establishment of dorsal-ventral polarity in the early C. elegans embryo

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Two maternal genes, apx-1 and pie-1, are required to distinguish the fates of equivalent blastomeres in the early Caenorhabditis elegans embryo

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lin-12 and glp-1 are required zygotically for early embryonic cellular interactions and are regulated by maternal GLP-1 signaling in Caenorhabditis elegans

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APX-1 can substitute for its homolog LAG-2 to direct cell interactions throughout Caenorhabditis elegans development.

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22 Translationally Coupled Degradation of mRNA in Eukaryotes

1996 • 17 citations