Nerve Growth Factor Protects PC12 Cells Against Peroxynitrite‐Induced Apoptosis via a Mechanism Dependent on Phosphatidylinositol 3‐Kinase

Peroxynitrite oxidation of sulfhydryls.

1991 • 2,479 citations

Apoptosis. Its significance in cancer and cancer Therapy

1994 • 2,148 citations

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1995 • 2,106 citations

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures.

1995 • 1,968 citations

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

1992 • 1,499 citations

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses

1993 • 1,148 citations

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF

1991 • 1,049 citations

Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts.

1996 • 771 citations

Inhibition of NIH 3T3 Cell Proliferation by a Mutant ras Protein with Preferential Affinity for GDP

1988 • 757 citations

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

1994 • 728 citations

Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide.

1994 • 596 citations

Ras-Dependent Induction of Cellular Responses by Constitutively Active Phosphatidylinositol-3 Kinase

1995 • 553 citations

One- and two-electron oxidations of methionine by peroxynitrite.

1994 • 318 citations

Acceleration of Peroxynitrite Oxidations by Carbon Dioxide

1996 • 277 citations

Sensitivity of the Essential Zinc-Thiolate Moiety of Yeast Alcohol Dehydrogenase to Hypochlorite and Peroxynitrite

1995 • 246 citations

Peroxynitrite Causes Apoptosis in Rat Thymocytes

1995 • 153 citations

The tyrosine kinase inhibitor tyrphostin blocks the cellular actions of nerve growth factor

1993 • 113 citations

Proliferative inhibition by dominant-negative Ras rescues naive and neuronally differentiated PC12 cells from apoptotic death.

1994 • 103 citations

Nerve growth factor receptors on chick embryo sympathetic ganglion cells: binding characteristics and development

1986 • 59 citations