Receptor binding and selectivity of three 11C-labelled dopamine receptor antagonists in the brain of Rhesus monkeys studied with positron emission tomography

A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography

1984 • 959 citations

Positron Emission Tomography Reveals Elevated D ₂ Dopamine Receptors in Drug-Naive Schizophrenics

1986 • 935 citations

Quantitative Analysis of D2 Dopamine Receptor Binding in the Living Human Brain by PET

1986 • 847 citations

Imaging Dopamine Receptors in the Human Brain by Positron Tomography

1983 • 743 citations

Effects of Age on Dopamine and Serotonin Receptors Measured by Positron Tomography in the Living Human Brain

1984 • 701 citations

Substituted benzamides as ligands for visualization of dopamine receptor binding in the human brain by positron emission tomography.

1985 • 304 citations

Quantification of Neuroreceptors in the Living Human Brain. I. Irreversible Binding of Ligands

1986 • 279 citations

Tolerability and therapeutic effect of clozapine

1985 • 277 citations

Association with persistent neuroleptic-induced dyskinesia of regional changes in brain GABA synthesis

1984 • 252 citations

CLOZAPINE AND HALOPERIDOL IN A SINGLE‐BLIND CROSS‐OVER TRIAL: THERAPEUTIC AND BIOCHEMICAL ASPECTS IN THE TREATMENT OF SCHIZOPHRENIA

1974 • 198 citations

Quantification of Neuroreceptors in the Living Human Brain. II. Inhibition Studies of Receptor Density and Affinity

1986 • 147 citations

In vivoevaluation of striatal dopamine reuptake sites using 11C-nomifensine and positron emission tomography

1987 • 146 citations

Receptor-Binding Profiles of Neuroleptics

1985 • 144 citations

Strategies for in vivo Measurement of Receptor Binding Using Positron Emission Tomography

1986 • 135 citations

Dopamine receptor properties in Parkinson's disease and Huntington's chorea evaluated by positron emission tomography using¹¹C-N-methyl-spiperone

1987 • 110 citations

Comparison of Three ¹⁸F‐Labeled Butyrophenone Neuroleptic Drugs in the Baboon Using Positron Emission Tomography

1985 • 107 citations

Kinetic Modeling of Receptor‐Ligand Binding Applied to Positron Emission Tomographic Studies with Neuroleptic Tracers

1987 • 98 citations

(3-N-[11C]methyl)spiperone, a ligand binding to dopamine receptors: radiochemical synthesis and biodistribution studies in mice.

1984 • 90 citations

A Four Ring Positron Camera System for Emission Tomography of the Brain

1982 • 77 citations

Clinical and epidemiologic aspects of tardive dyskinesia.

1985 • 72 citations

Clozapine (Leponex) compared with chlorpromazine: a double-blind evaluation of pharmacological and clinical properties.

1974 • 71 citations

Positron emission tomography (PET) in the study of dopamine receptors in the primate brain: evaluation of a kinetic model using¹¹C-N-methyl-spiperone

1987 • 40 citations

Receptor binding of N-(methyl-11C) clozapine in the brain of rhesus monkey studied by positron emission tomography (PET)

1986 • 38 citations