Involvement of the Molecular Chaperone Ydj1 in the Ubiquitin-Dependent Degradation of Short-Lived and Abnormal Proteins in Saccharomyces cerevisiae

Current protocols in molecular biology

1988 • 4,543 citations

In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue

1986 • 1,942 citations

Methods in Yeast Genetics: A Laboratory Course Manual

1990 • 1,922 citations

The ubiquitin-proteasome proteolytic pathway

1994 • 1,778 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells

1974 • 1,775 citations

MOLECULAR CHAPERONE FUNCTIONS OF HEAT-SHOCK PROTEINS

1993 • 1,591 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION

1992 • 1,402 citations

70K heat shock related proteins stimulate protein translocation into microsomes

1988 • 1,276 citations

Methods in Yeast Genetics — A Laboratory Course Manual

1991 • 1,257 citations

Role of the Major Heat Shock Proteins as Molecular Chaperones

1993 • 1,096 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells: Part 2

1976 • 1,060 citations

Heat shock proteins: molecular chaperones of protein biogenesis

1993 • 598 citations

THE UBIQUITIN-CONJUGATION SYSTEM

1992 • 561 citations

Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins.

1990 • 520 citations

Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins

1995 • 492 citations

The multicatalytic and 26 S proteases.

1993 • 476 citations

DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70

1994 • 473 citations

The N-end rule

1992 • 464 citations

Hip, a novel cochaperone involved in the eukaryotic hsc70/hsp40 reaction cycle

1995 • 436 citations

DnaK, DnaJ, and GrpE heat shock proteins negatively regulate heat shock gene expression by controlling the synthesis and stability of sigma 32.

1990 • 356 citations

Functions of the Proteasome: the Lysis at the End of the Tunnel

1995 • 302 citations

YDJ1p facilitates polypeptide translocation across different intracellular membranes by a conserved mechanism

1992 • 280 citations

Regulated degradation of the transcription factor Gcn4.

1994 • 271 citations

The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme.

1991 • 268 citations

Regulation of Hsp70 function by a eukaryotic DnaJ homolog.

1992 • 262 citations

Ubiquitin as a degradation signal.

1992 • 261 citations

PRE2, highly homologous to the human major histocompatibility complex-linked RING10 gene, codes for a yeast proteasome subunit necessary for chrymotryptic activity and degradation of ubiquitinated proteins.

1993 • 260 citations

Molecular chaperones cooperate with PIM1 protease in the degradation of misfolded proteins in mitochondria.

1994 • 237 citations

Three proteolytic systems in the yeast saccharomyces cerevisiae

1991 • 228 citations

DnaK and DnaJ heat shock proteins participate in protein export in Escherichia coli.

1992 • 214 citations

Cooperation of GroEL/GroES and DnaK/DnaJ heat shock proteins in preventing protein misfolding in Escherichia coli.

1992 • 214 citations

Escherichia coli heat shock gene mutants are defective in proteolysis.

1988 • 205 citations

Involvement of the chaperonin dnaK in the rapid degradation of a mutant protein in Escherichia coli.

1992 • 199 citations

A New Inhibitor of the Chymotrypsin‐Like Activity of the Multicatalytic Proteinase Complex (20S Proteasome) Induces Accumulation of Ubiquitin‐Protein Conjugates in a Neuronal Cell

1994 • 183 citations

Modulation of stability of the Escherichia coli heat shock regulatory factor sigma

1989 • 169 citations

The yeast SIS1 protein, a DnaJ homolog, is required for the initiation of translation

1993 • 150 citations

Molecular chaperones involved in protein degradation in the endoplasmic reticulum: quantitative interaction of the heat shock cognate protein BiP with partially folded immunoglobulin light chains that are degraded in the endoplasmic reticulum.

1995 • 145 citations

Rapid degradation of an abnormal protein in Escherichia coli involves the chaperones GroEL and GroES.

1994 • 128 citations

The Molecular Chaperone Ydj1 Is Required for the p34^CDC28-Dependent Phosphorylation of the Cyclin Cln3 That Signals Its Degradation

1996 • 71 citations

Proteolysis in Heat-stressed HeLa Cells

1989 • 19 citations