Trans-9-octadecenoic acid is biologically neutral and does not regulate the low density lipoprotein receptor as the cis isomer does in the hamster.

Direct transesterification of all classes of lipids in a one-step reaction.

1986 • 2,353 citations

Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults

1988 • 2,276 citations

Regression of Coronary Artery Disease as a Result of Intensive Lipid-Lowering Therapy in Men with High Levels of Apolipoprotein B

1990 • 2,192 citations

Effect of dietary fatty acids on serum lipids and lipoproteins. A meta-analysis of 27 trials.

1992 • 1,487 citations

Effect of Dietary trans Fatty Acids on High-Density and Low-Density Lipoprotein Cholesterol Levels in Healthy Subjects

1990 • 1,434 citations

Relation of Serum Lipoprotein Levels and Systolic Blood Pressure to Early Atherosclerosis

1986 • 1,069 citations

Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans

1993 • 880 citations

Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. The Expert Panel

1988 • 536 citations

Role of acyl-CoA: cholesterol acyltransferase in cellular cholesterol metabolism.

1985 • 519 citations

Dietarytrans fatty acids: effects on plasma lipids and lipoproteins of healthy men and women

1994 • 470 citations

Hydrogenation alternatives: effects of trans fatty acids and stearic acid versus linoleic acid on serum lipids and lipoproteins in humans.

1992 • 455 citations

Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia

1984 • 442 citations

Regulatory role for hepatic low density lipoprotein receptors in vivo in the dog.

1981 • 424 citations

Sterol synthesis in vivo in 18 tissues of the squirrel monkey, guinea pig, rabbit, hamster, and rat

1983 • 414 citations

Relative importance of high and low density lipoproteins in the regulation of cholesterol synthesis in the adrenal gland, ovary, and testis of the rat.

1978 • 386 citations

Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells.

1993 • 378 citations

Interaction of dietary cholesterol and triglycerides in the regulation of hepatic low density lipoprotein transport in the hamster.

1988 • 364 citations

Dietary saturated triacylglycerols suppress hepatic low density lipoprotein receptor activity in the hamster.

1985 • 318 citations

The Formation of Cholesterol Esters with Rat Liver Enzymes

1964 • 304 citations

Rat liver acyl-coenzyme A:cholesterol acyltransferase: its regulation in vivo and some of its properties in vitro

1980 • 241 citations

Tissue sites of degradation of apoprotein A-I in the rat.

1983 • 241 citations

Saturated and unsaturated fatty acids independently regulate low density lipoprotein receptor activity and production rate.

1992 • 240 citations

Regulation of Plasma LDL-Cholesterol Levels by Dietary Cholesterol and Fatty Acids

1993 • 240 citations

Rates of receptor-dependent and -independent low density lipoprotein uptake in the hamster.

1983 • 230 citations

Metabolic Studies in Familial Hypercholesterolemia

1979 • 217 citations

Rates of sterol synthesis and uptake in the major organs of the rat in vivo.

1981 • 212 citations

Delayed clearance of very low density and intermediate density lipoproteins with enhanced conversion to low density lipoprotein in WHHL rabbits.

1982 • 207 citations

Measurement of rates of cholesterol synthesis using tritiated water

1984 • 204 citations

Hydrogenation impairs the hypolipidemic effect of corn oil in humans. Hydrogenation, trans fatty acids, and plasma lipids.

1993 • 174 citations

Fatty acids regulate hepatic low density lipoprotein receptor activity through redistribution of intracellular cholesterol pools.

1992 • 148 citations

Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster.

1994 • 145 citations

Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia

1982 • 143 citations

Validation of a dual-isotope plasma ratio method for measurement of cholesterol absorption in rats

1974 • 141 citations

Regulatory effects of the saturated fatty acids 6:0 through 18:0 on hepatic low density lipoprotein receptor activity in the hamster.

1992 • 128 citations

Kinetic constants for receptor-dependent and receptor-independent low density lipoprotein transport in the tissues of the rat and hamster.

1986 • 121 citations

Receptor-independent low density lipoprotein transport in the rat in vivo. Quantitation, characterization, and metabolic consequences.

1985 • 116 citations

Metabolism of lipoproteins containing apolipoprotein B-100 in blood plasma of rabbits: heterogeneity related to the presence of apolipoprotein E.

1986 • 107 citations

Mechanisms by which saturated triacylglycerols elevate the plasma low density lipoprotein-cholesterol concentration in hamsters. Differential effects of fatty acid chain length.

1989 • 104 citations

Dietary fatty acids regulate hepatic low density lipoprotein (LDL) transport by altering LDL receptor protein and mRNA levels.

1993 • 101 citations

Role of receptor-independent low density lipoprotein transport in the maintenance of tissue cholesterol balance in the normal and WHHL rabbit.

1986 • 85 citations

Bile acids regulate hepatic low density lipoprotein receptor activity in the hamster by altering cholesterol flux across the liver.

1986 • 84 citations

Hydrogenation Impairs the Hypolipidemic Effect of Corn Oil in Humans

1993 • 72 citations

Properties of a solubilised and reconstituted preparation of ACYL-CoA:cholesterol acyltransferase from rat liver

1982 • 67 citations

Effect of geometry and position of ethylenic bond upon acyl coenzyme A-cholesterol-O-acyltransferase

1970 • 56 citations

Dual modulation of hepatic and intestinal acyl‐CoA: cholesterol acyltransferase activity by (de‐)phosphorylation and substrate supply in vitro

1983 • 54 citations

Metabolism of apoprotein B in selectively bred baboons with low and high levels of low density lipoproteins.

1988 • 28 citations

In vivo modulation of rat liver acyl‐coenzyme A:cholesterol acyltransferase by phosphorylation and substrate supply

1983 • 19 citations

Regulation of Plasma Low Density Lipoprotein Levels: New Strategies for Drug Design

1987 • 16 citations