Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Biostatistical Analysis.

1975 • 10,200 citations

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

1977 • 2,481 citations

Determination of free amino groups in proteins by trinitrobenzenesulfonic acid

1966 • 2,029 citations

The Theory of Tracer Experiments with ¹³¹I-Labelled Plasma Proteins

1957 • 834 citations

The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia

1972 • 629 citations

Role of lysine residues of plasma lipoproteins in high affinity binding to cell surface receptors on human fibroblasts.

1978 • 621 citations

Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit) *1Incidence and development of atherosclerosis and xanthoma

1980 • 540 citations

Cholestyramine Promotes Receptor-Mediated Low-Density-Lipoprotein Catabolism

1980 • 357 citations

Atherosclerosis: The low-density lipoprotein receptor hypothesis

1977 • 341 citations

Characterization of plasma lipoproteins separated and purified by agarose-column chromatography

1974 • 330 citations

Altered Metabolism (In Vivo and In Vitro) of Plasma Lipoproteins after Selective Chemical Modification of Lysine Residues of the Apoproteins

1979 • 313 citations

Defects of receptor-mediated low density lipoprotein catabolism in homozygous familial hypercholesterolemia and hypothyroidism in vivo.

1981 • 278 citations

Deficiency of low density lipoprotein receptors in liver and adrenal gland of the WHHL rabbit, an animal model of familial hypercholesterolemia.

1981 • 254 citations

Reduction in cholesterol and low density lipoprotein synthesis after portacaval shunt surgery in a patient with homozygous familial hypercholesterolemia.

1975 • 245 citations

THE LDL RECEPTOR LOCUS AND THE GENETICS OF FAMILIAL HYPERCHOLESTEROLEMIA

1979 • 233 citations

Metabolic Studies in Familial Hypercholesterolemia

1979 • 217 citations

WHHL‐Rabbit: a low density lipoprotein receptor‐deficient animal model for familial hypercholesterolemia

1980 • 190 citations

Receptor-mediated low density lipoprotein catabolism in man.

1979 • 182 citations

Effects of cholestyramine on receptor-mediated plasma clearance and tissue uptake of human low density lipoproteins in the rabbit.

1980 • 145 citations

Separate mechanisms for the uptake of high and low density lipoproteins by mouse adrenal gland in vivo.

1979 • 136 citations

Inhibition of receptor-mediated clearance of lysine and arginine modified lipoproteins from the plasma of rats and monkeys

1980 • 120 citations

Kinetic analysis of turnover data.

1979 • 87 citations

Accelerated clearance of low-density and high-density lipoproteins and retarded clearance of E apoprotein-containing lipoproteins from the plasma of rats after modification of lysine residues

1979 • 71 citations

Low density lipoprotein receptor deficiency in cultured hepatocytes of the WHHL rabbit. Further evidence of two pathways for catabolism of exogenous proteins.

1981 • 65 citations

Hypolipidemic effects of CS-500 (ML-236B) in WHHL-rabbit, a heritable animal model for hyperlipidemia

1981 • 51 citations

Biochemical Characterization of Skin Fibroblasts Derived from WHHL-Rabbit, a Notable Animal Model for Familial Hypercholesterolemia

1981 • 41 citations

Lipid Research Clinics Program

1984 • 5 citations