Protein Kinase G Mediates Vascular Endothelial Growth Factor-induced Raf-1 Activation and Proliferation in Human Endothelial Cells

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

The Biology of Vascular Endothelial Growth Factor

1997 • 4,359 citations

The MAPK signaling cascade

1995 • 3,300 citations

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

1991 • 2,499 citations

The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor

1992 • 2,042 citations

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways

1996 • 1,519 citations

Protein kinase Cα activates RAF-1 by direct phosphorylation

1993 • 1,282 citations

Nitric Oxide Synthases: Properties and Catalytic Mechanism

1995 • 1,275 citations

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

1994 • 1,012 citations

Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P.

1994 • 858 citations

Intracellular cyclic GMP receptor proteins

1993 • 655 citations

Vascular Endothelial Growth Factor, a Potent and Selective Angiogenic Agent

1996 • 570 citations

Protein Kinase C δ Activates the MEK-ERK Pathway in a Manner Independent of Ras and Dependent on Raf

1996 • 570 citations

The pathway to signal achievement

1993 • 563 citations

A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF.

1995 • 480 citations

Inhibition of smooth muscle cell growth by nitric oxide and activation of cAMP-dependent protein kinase by cGMP

1994 • 467 citations

Nitric Oxide Is an Upstream Signal of Vascular Endothelial Growth Factor-induced Extracellular Signal-regulated Kinase½ Activation in Postcapillary Endothelium

1998 • 436 citations

Upregulation of vascular endothelial growth factor expression induced by myocardial ischaemia: implications for coronary angiogenesis

1994 • 430 citations

Vascular Endothelial Growth Factor/Vascular Permeability Factor Augments Nitric Oxide Release From Quiescent Rabbit and Human Vascular Endothelium

1997 • 406 citations

Distinct and specific functions of cGMP-dependent protein kinases

1997 • 394 citations

Nitric Oxide-stimulated Guanine Nucleotide Exchange on p21ras

1995 • 367 citations

The potential for isoenzyme‐selective modulation of protein kinase C

1997 • 343 citations

Differential Activation of Mitogen-activated Protein Kinases by Nitric Oxide-related Species

1996 • 332 citations

Tumor-secreted vascular permeability factor increases cytosolic Ca2+ and von Willebrand factor release in human endothelial cells.

1991 • 325 citations

Ras target proteins in eukaryotic cells

1995 • 316 citations

Mechanism of inhibition of Raf-1 by protein kinase A.

1994 • 311 citations

Nitric oxide and nitric oxide-generating agents induce a reversible inactivation of protein kinase C activity and phorbol ester binding.

1993 • 302 citations

Human Vascular Permeability Factor

1989 • 282 citations

Stimulation of intestinal Cl- transport by heat-stable enterotoxin: activation of cAMP-dependent protein kinase by cGMP

1992 • 265 citations

Angiotensin II stimulation of rapid protein tyrosine phosphorylation and protein kinase activation in rat aortic smooth muscle cells.

1993 • 251 citations

Parvalbumin relaxes frog skeletal muscle when sarcoplasmic reticulum Ca(2+)-ATPase is inhibited

1996 • 215 citations

Determination of the number of endothelial cells in culture using an acid phosphatase assay

1986 • 206 citations

Nitric oxide and cGMP analogs activate transcription from AP‐1‐responsive promoters in mammalian cells

1995 • 193 citations

Inhibition of Endothelial Nitric Oxide Synthase Activity by Protein Kinase C

1995 • 188 citations

Regulation of Gene Expression by cGMP-dependent Protein Kinase

1996 • 146 citations

Nitric Oxide Promotes DNA Synthesis and Cyclic GMP Formation in Endothelial Cells from Postcapillary Venules

1993 • 125 citations

Biology of the protein kinase C family

1989 • 120 citations

Signal Transduction by the Phosphatidylinositol Cycle in Myocardium

1995 • 69 citations

[14] Cyclic GMP-dependent protein kinase in nitric oxide signaling

1996 • 67 citations

Regulation of Protein Kinase C: A Tale of Lipids and Proteins

1996 • 57 citations

Protein Kinase A and Protein Kinase C Synergistically Activate the -1 Kinase/Mitogen-activated Protein Kinase Cascade in Neonatal Rat Cardiomyocytes

1997 • 43 citations

Phorbol Ester and Interleukin-1 Induce Interleukin-6 Gene Expression in Vascular Smooth Muscle Cells Via Independent Pathways

1997 • 25 citations