Biogenesis of hepatitis C virus envelope glycoproteins

The GxxxG motif: A framework for transmembrane helix-helix association

2000 • 905 citations

Expression and identification of hepatitis C virus polyprotein cleavage products

1993 • 890 citations

VIRUS-CELL AND CELL-CELL FUSION

1996 • 559 citations

Overview of Hepatitis C Virus Genome Structure, Polyprotein Processing, and Protein Properties

2000 • 505 citations

Folding and Assembly of Viral Membrane Proteins

1993 • 447 citations

Formation and intracellular localization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia and Sindbis viruses

1994 • 423 citations

Formation of native hepatitis C virus glycoprotein complexes

1997 • 322 citations

A Retention Signal Necessary and Sufficient for Endoplasmic Reticulum Localization Maps to the Transmembrane Domain of Hepatitis C Virus Glycoprotein E2

1998 • 252 citations

Lectins as chaperones in glycoprotein folding

1998 • 233 citations

Role of potentially charged transmembrane residues in targeting proteins for retention and degradation within the endoplasmic reticulum.

1991 • 215 citations

Hepatitis C virus glycoprotein folding: disulfide bond formation and association with calnexin

1996 • 208 citations

Hepatitis C virus: Detection of intracellular virus particles by electron microscop

1996 • 195 citations

Functional Analysis of Cell Surface-Expressed Hepatitis C Virus E2 Glycoprotein

1999 • 190 citations

Characterization of truncated forms of hepatitis C virus glycoproteins.

1997 • 185 citations

Involvement of Endoplasmic Reticulum Chaperones in the Folding of Hepatitis C Virus Glycoproteins

1998 • 179 citations

Charged Residues in the Transmembrane Domains of Hepatitis C Virus Glycoproteins Play a Major Role in the Processing, Subcellular Localization, and Assembly of These Envelope Proteins

2000 • 174 citations

The Transmembrane Domains of Hepatitis C Virus Envelope Glycoproteins E1 and E2 Play a Major Role in Heterodimerization

2000 • 157 citations

The Transmembrane Domain of Hepatitis C Virus Glycoprotein E1 Is a Signal for Static Retention in the Endoplasmic Reticulum

1999 • 155 citations

Hepatitis C Virus Glycoprotein Complex Localization in the Endoplasmic Reticulum Involves a Determinant for Retention and Not Retrieval

1998 • 147 citations

Complex Processing and Protein:Protein Interactions in the E2:NS2 Region of HCV

1994 • 133 citations

Cell Fusion Activity of Hepatitis C Virus Envelope Proteins

2000 • 129 citations

Folding, Assembly and Subcellular Localization of Hepatitis C Virus Glycoproteins

2000 • 122 citations

Analysis of the glycosylation sites of hepatitis C virus (HCV) glycoprotein E1 and the influence of E1 glycans on the formation of the HCV glycoprotein complex.

1999 • 120 citations

Activation of the grp78 and grp94 Promoters by Hepatitis C Virus E2 Envelope Protein

1999 • 114 citations

Processing of E1 and E2 Glycoproteins of Hepatitis C Virus Expressed in Mammalian and Insect Cells

1994 • 114 citations

Analysis of Hepatitis C Virus Capsid, E1, and E2/NS1 Proteins Expressed in Insect Cells

1993 • 113 citations

Protein Localization and Virus Assembly at Intracellular Membranes

1991 • 101 citations

Characterization of Human Monoclonal Antibodies Specific to the Hepatitis C Virus Glycoprotein E2 within VitroBinding Neutralization Properties

1998 • 83 citations

The role of the hepatitis C virus glycoproteins in infection

2000 • 80 citations

The Transmembrane Domain of the Hepatitis C Virus E2 Glycoprotein Is Required for Correct Folding of the E1 Glycoprotein and Native Complex Formation

2001 • 73 citations

Glycosylation of the Hepatitis C Virus Envelope Protein E1 Is Dependent on the Presence of a Downstream Sequence on the Viral Polyprotein

2000 • 58 citations

The C-terminal region of the hepatitis C virus E1 glycoprotein confers localization within the endoplasmic reticulum

1999 • 49 citations

Coexpression of hepatitis C virus envelope proteins E1 and E2 in cis improves the stability of membrane insertion of E2

2001 • 46 citations

Delineation of Regions Important for Heteromeric Association of Hepatitis C Virus E1 and E2

1997 • 45 citations

Characterization of Modified Hepatitis C Virus E2 Proteins Expressed on the Cell Surface

2000 • 44 citations

Characterization of aggregates of hepatitis C virus glycoproteins

1999 • 39 citations

Alanine Insertion Scanning Mutagenesis of Lactose Permease Transmembrane Helices

1997 • 38 citations

Hepatitis C Virus Structural Proteins Reside in the Endoplasmic Reticulum as Well as in the Intermediate Compartment/cis-Golgi Complex Region of Stably Transfected Cells

2001 • 38 citations

A New Determinant of Endoplasmic Reticulum Localization Is Contained in the Juxtamembrane Region of the Ectodomain of Hepatitis C Virus Glycoprotein E1

2000 • 31 citations

Covalent interactions are not required to permit or stabilize the non-covalent association of hepatitis C virus glycoproteins E1 and E2.

1999 • 26 citations