Significance of myocardial alpha- and beta-adrenoceptors in catecholamine-induced cardiac hypertrophy.

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Norepinephrine-stimulated hypertrophy of cultured rat myocardial cells is an alpha 1 adrenergic response.

1983 • 618 citations

Stimulation of hypertrophy of cultured neonatal rat heart cells through an alpha 1-adrenergic receptor and induction of beating through an alpha 1- and beta 1-adrenergic receptor interaction. Evidence for independent regulation of growth and beating.

1985 • 485 citations

Development and proliferative capacity of cardiac muscle cells.

1974 • 319 citations

Alpha 1-adrenergic and muscarinic cholinergic stimulation of phosphoinositide hydrolysis in adult rat cardiomyocytes.

1985 • 298 citations

Myocardial Hypertrophy Produced by Chronic Infusion of Subhypertensive Doses of Norepinephrine in the Dog

1973 • 264 citations

Cardiac myocyte hypertrophy is associated with c-myc protooncogene expression.

1986 • 263 citations

Reversal of left ventricular hypertrophy in hypertensive patients treated with methyldopa

1982 • 235 citations

Studies on isoproterenol-induced cardiomegaly in rats

1969 • 215 citations

Cardiac Sympathetic Nerves as the Final Common Pathway in the Induction of Adaptive Cardiac Hypertrophy

1981 • 185 citations

?2-Adrenoceptor-mediated positive inotropic effect of adrenaline in human ventricular myocardium

1987 • 163 citations

Hemodynamic versus adrenergic control of cat right ventricular hypertrophy.

1985 • 146 citations

Myocardial necrosis, fibrosis, and DNA synthesis in experimental cardiac hypertrophy induced by sudden pressure overload.

1976 • 130 citations

Existence and functional role of alpha1-adrenoceptors in the mammalian heart

1985 • 121 citations

Substances interfering with spectrophotometric estimation of nucleic acids and their elimination by the two-wavelength method

1960 • 113 citations

Activities of octopamine and synephrine stereoisomers on α‐adrenoceptors

1988 • 107 citations

β-Adrenergic activities of octopamine and synephrine stereoisomers on guinea-pig atria and trachea

1987 • 64 citations

Molecular Aspects of Cardiac Hypertrophy

1979 • 59 citations

Measurement of left ventricular hemodynamic parameters in closed-chest rats under control and various pathophysiologic conditions

1983 • 57 citations

Alpha-adrenergic receptors on rat ventricular myocytes: characteristics and linkage to cAMP metabolism

1986 • 48 citations

The influence of sympathetic nervous activity on regression of cardiac hypertrophy.

1985 • 46 citations

Absence of hypertension despite chronic marked elevations in plasma norepinephrine in conscious dogs.

1987 • 43 citations

Role of endocrine factors in the pathogenesis of cardiac hypertrophy.

1974 • 42 citations

Contraction regulates myosin synthesis and myosin content of cultured heart cells

1985 • 37 citations

Evidence that phosphoinositide response is mediated by α1-adrenoceptor stimulation, but not linked with excitation-contraction coupling in cardiac muscle

1986 • 36 citations

Metabolic aspects of the development of experimental cardiac hypertrophy

1986 • 34 citations

Metabolic and cardiovascular responses to prolonged noradrenaline load and their antagonism by beta blockade in the rat

1978 • 34 citations

Quantification of myocardial necrosis and cardiac hypertrophy in isoproterenol-treated rats.

1987 • 29 citations

Regression of Cardiac Hypertrophy

1987 • 22 citations

Triiodothyronine-induced changes in function, metabolism and weight of the rat heart: Effects of α- and β-adrenergic blockade

1989 • 19 citations

Role of Adrenergic Mechanisms in the Development of Cardiac Hypertrophy

1975 • 18 citations

Correlation between haemodynamic and metabolic changes in three models of experimental cardiac hypertrophy

1984 • 9 citations

Ventricular Hypertrophy — Physiological Mechanisms

1986 • 8 citations