A liver-specific factor essential for albumin transcription differs between differentiated and dedifferentiated rat hepatoma cells.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

PROTEIN-DNA RECOGNITION

1984 • 1,649 citations

Tissue-specific in vitro transcription from the mouse albumin promoter

1986 • 1,322 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication

1987 • 1,050 citations

Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors

1986 • 883 citations

Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro

1985 • 805 citations

Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes

1980 • 772 citations

A multiplicity of CCAAT box-binding proteins

1987 • 745 citations

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

1986 • 740 citations

Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.

1987 • 631 citations

Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay.

1985 • 575 citations

Homologous recognition of a promoter domain common to the MSV LTR and the HSV tk gene

1986 • 562 citations

The interplay of DNA-binding proteins on the promoter of the mouse albumin gene

1987 • 532 citations

Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene

1987 • 516 citations

Interaction of a Liver-Specific Nuclear Factor with the Fibrinogen and α ₁ -Antitrypsin Promoters

1987 • 485 citations

An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice.

1987 • 443 citations

A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor.

1986 • 412 citations

Identification and purification of a polypeptide that binds to the c-fos serum response element.

1987 • 398 citations

Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro

1987 • 386 citations

Characterization of differentiated and dedifferentiated clones from a rat hepatoma

1975 • 381 citations

Factors involved in control of tissue-specific expression of albumin gene

1987 • 367 citations

Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors

1987 • 356 citations

The L- and R-type isozymes of rat pyruvate kinase are produced from a single gene by use of different promoters.

1987 • 332 citations

Inducible binding of a factor to the c-fos enhancer

1986 • 310 citations

A pituitary-specific trans-acting factor can stimulate transcription from the growth hormone promoter in extracts of nonexpressing cells

1987 • 301 citations

Several distinct "CCAAT" box binding proteins coexist in eukaryotic cells.

1988 • 230 citations

Multiple regulatory elements in the intergenic region between the alpha-fetoprotein and albumin genes.

1986 • 205 citations

Tissue-specific expression is conferred by a sequence from the 5′ end of the rat albumin gene.

1984 • 202 citations

The TGGCA-binding protein: a eukaryotic nuclear protein recognizing a symmetrical sequence on double-stranded linear DNA

1984 • 191 citations

Cis- and trans-acting elements responsible for the cell-specific expression of the human alpha 1-antitrypsin gene.

1987 • 178 citations

Determinants of Rat Albumin Promoter Tissue Specificity Analyzed by an Improved Transient Expression System

1987 • 166 citations

Dedifferentiated variants of a rat hepatoma: Reversion analysis

1980 • 129 citations

The human haptoglobin gene: transcriptional regulation during development and acute phase induction.

1987 • 128 citations

Immunofluorescence analysis of the time-course of extinction, reexpression, and activation of albumin production in rat hepatoma-mouse fibroblast heterokaryons and hybrids.

1981 • 114 citations

Dedifferentiated variants of a rat hepatoma: Analysis by cell hybridization

1979 • 106 citations

Hepatocyte-specific promoter element HP1 of the Xenopus albumin gene interacts with transcriptional factors of mammalian hepatocytes

1988 • 105 citations

Changing patterns of transcriptional and post-transcriptional control of liver-specific gene expression during rat development.

1987 • 101 citations

Tissue-specific expression of the rat albumin gene: genetic control of its extinction in microcell hybrids.

1986 • 100 citations

Binding of Drosophila heat-shock gene transcription factor to the hsp 70 promoter. Evidence for symmetric and dynamic interactions.

1986 • 93 citations

Liver-Specific RNA Metabolism in Hepatoma Cells: Variations in Transcription Rates and mRNA Levels

1985 • 91 citations

Factors that interact with the rat albumin promoter are present both in hepatocytes and other cell types.

1987 • 86 citations

Expression of the albumin gene in rat hepatoma cells and their dedifferentiated variants

1981 • 66 citations

Expression of fetal and neonatal hepatic functions by mouse hepatoma-rat hepatoma hybrids

1979 • 52 citations

The rat α₁-fetoprotein gene: characterization of the 5′-flanking region and tandem organization with the albumin gene

1987 • 33 citations

Dedifferentiated variants of a rat hepatoma: Partial reversion induced by cell aggregation

1980 • 28 citations

Albumin extinction without methylation of its gene.

1984 • 14 citations