Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

1996 • 1,473 citations

G Protein-coupled Receptors

1998 • 1,033 citations

Control of EGF Receptor Signaling by Clathrin-Mediated Endocytosis

1996 • 998 citations

Regulation of tyrosine kinase cascades by G-protein-coupled receptors

1999 • 688 citations

Signal characteristics of G protein-transactivated EGF receptor

1997 • 669 citations

Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase

1998 • 542 citations

Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway

1995 • 541 citations

Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor

1997 • 456 citations

Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors

1997 • 454 citations

A highly conserved tyrosine residue in G protein-coupled receptors is required for agonist-mediated beta 2-adrenergic receptor sequestration.

1994 • 361 citations

Src-mediated Tyrosine Phosphorylation of Dynamin Is Required for β2-Adrenergic Receptor Internalization and Mitogen-activated Protein Kinase Signaling

1999 • 259 citations

Pleiotropic Coupling of G Protein-coupled Receptors to the Mitogen-activated Protein Kinase Cascade

1999 • 259 citations

G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts

1997 • 233 citations

Endocytosis of Functional Epidermal Growth Factor Receptor-Green Fluorescent Protein Chimera

1998 • 228 citations

Modulation of the Arrestin-Clathrin Interaction in Cells

1997 • 193 citations

Subtype-Specific Intracellular Trafficking of α₂-Adrenergic Receptors

1997 • 181 citations

The β3-Adrenergic Receptor Activates Mitogen-activated Protein Kinase in Adipocytes through a Gi-dependent Mechanism

1999 • 179 citations

Insulin-like Growth Factor-I Receptor Internalization Regulates Signaling via the Shc/Mitogen-activated Protein Kinase Pathway, but Not the Insulin Receptor Substrate-1 Pathway

1998 • 159 citations

Serotonin 5-HT1A Receptor-mediated Erk Activation Requires Calcium/Calmodulin-dependent Receptor Endocytosis

1999 • 157 citations

U50,488H-induced Internalization of the Human κ Opioid Receptor Involves a β-Arrestin- and Dynamin-dependent Mechanism

1999 • 147 citations

Role of Arrestins in Endocytosis and Signaling of α2-Adrenergic Receptor Subtypes

1999 • 136 citations

Requirement of Receptor Internalization for Opioid Stimulation of Mitogen-Activated Protein Kinase: Biochemical and Immunofluorescence Confocal Microscopic Evidence

1999 • 127 citations

Role of Clathrin-mediated Endocytosis in CXCR2 Sequestration, Resensitization, and Signal Transduction

1999 • 116 citations

Regulation of Muscarinic Acetylcholine Receptor Sequestration and Function by β-Arrestin

1999 • 114 citations

Dissociation of Functional Roles of Dynamin in Receptor-mediated Endocytosis and Mitogenic Signal Transduction

1999 • 112 citations

Stimulation of Mitogen-activated Protein Kinase by G Protein-coupled α2-Adrenergic Receptors Does Not Require Agonist-elicited Endocytosis

1999 • 105 citations

Activation of the Mitogen-activated Protein Kinase Pathway by a Gq/11-coupled Muscarinic Receptor Is Independent of Receptor Internalization

1999 • 83 citations

A Mutation in the Second Transmembrane Region of the CB1 Receptor Selectively Disrupts G Protein Signaling and Prevents Receptor Internalization

1999 • 66 citations

Activation of mitogen‐activated protein kinase by the bradykinin B₂ receptor is independent of receptor phosphorylation and phosphorylation‐triggered internalization

1999 • 29 citations